Table 1 Population characteristics of the follow-up study on Balkan Endemic Nephropathy
|  |  | Investigation in 2005–2006 | Investigation in 2006–2007 | ||
|---|---|---|---|---|---|
| Â | Â | Offspring of BEN cases | Offspring of control patients | Offspring of BEN cases | Offspring of control patients |
| Â | Â | n = 106 % | n = 94 % | n = 101 % | n = 92 % |
Parental history of BEN | Both | 30.2 | 0 | 30.7 | 0 |
| Â | Mother only | 32.1 | 0 | 32.7 | 0 |
| Â | Father only | 37.4 | 0 | 36.6 | 0 |
| Â | none | 0 | 100 | 0 | 100 |
Gender | male | 47.2 | 46.8 | 47.5 | 46.7 |
Age (years) | ≤ 40 | 11.3 | 21.3 | 8.9 | 19.6 |
|  | 40–50 | 35.9 | 34.0 | 35.6 | 34.8 |
|  | > 50–60 | 34.0 | 29.8 | 34.7 | 30.4 |
| Â | 60 & older | 18.9 | 14.9 | 20.8 | 15.2 |
Smoking in the last 12 mths | Â | 37.5 | 38.3 | 35.6 | 35.9 |
Ex-smoking | Â | 21.6 | 10.4 | 16.8 | 13.4 |
History of: pyelonephritis | Â | 8.5 | 2.1 | 8.9 | 2.2 |
kidney stones | Â | 9.4 | 6.4 | 11.9 | 5.4 |
cystitis | Â | 5.7 | 6.4 | 5.9 | 6.5 |
other kidney diseases | Â | 3.8 | 2.1 | 5.9 | 2.2 |
Diabetes mellitus | Â | 2.8 | 7.5 | 5.9 | 8.7 |
Report of application of the following medications: Anti-diabetics | Â | 0.9 | 2.1 | 2.0 | 2.2 |
Beta-blockers | Â | 8.5 | 1.1 | 7.0 | 2.2 |
Steroid hormones | Â | 6.0 | 0 | 0 | 2.2 |
|  |  | Median (5 – 98% value) | |||
Age | (years) | 51 (38–65) | 48 (34–65) | 52 (39–65) | 49 (34–66) |
Body-mass index | (kg/m2) | 28.0 (19.5–35.7) | 26.3 (21.4–33) | 28.5 (19.8–35.0) | 27.2 (21.5–34.3) |