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  1. Research article

    A low initial serum sodium level is associated with an increased risk of overcorrection in patients with chronic profound hyponatremia: a retrospective cohort analysis

    Even with abundant evidence for osmotic demyelination in patients with hyponatremia, the risk factors for overcorrection have not been fully investigated. Therefore the purpose of this study is to clarify the ...

    Sae Aratani, Masahiko Hara, Masahiko Nagahama, Fumika Taki, Miyuki Futatsuyama, Shuichi Tsuruoka and Yasuhiro Komatsu

    BMC Nephrology 2017 18:316

    Published on: 18 October 2017

  2. Research article

    Thymosin β4 alleviates renal fibrosis and tubular cell apoptosis through TGF-β pathway inhibition in UUO rat models

    Thymosin β4 (Tβ4) is closely associated with the cytoskeleton, inflammation, wound healing, angiogenesis, apoptosis, and myocardial regeneration, but the effects of Tβ4 treatment on chronic renal tubular inter...

    Jing Yuan, Yan Shen, Xia Yang, Ying Xie, Xin Lin, Wen Zeng, Yingting Zhao, Maolu Tian and Yan Zha

    BMC Nephrology 2017 18:314

    Published on: 18 October 2017

  3. Case report

    Bowel perforation by a peritoneal dialysis catheter: report of two cases

    Complications of peritoneal dialysis (PD) such as pain and catheter leakage are frequently reported. Delayed bowel perforation of a PD catheter is a rare adverse event but a serious complication associated wit...

    Maki Fujiwara, Takeshi Soda, Takuya Okada, Hiroshi Kanamaru, Takahiro Inoue and Osamu Ogawa

    BMC Nephrology 2017 18:312

    Published on: 16 October 2017

  4. Research article

    Clinical features and CKD-related quality of life in patients with CKD G3a and CKD G3b in China: results from the Chinese Cohort Study of Chronic Kidney Disease (C-STRIDE)

    This study aimed to compare clinical features and health-related quality of life (HRQoL) in the Chinese chronic kidney disease (CKD) 3 population and determined the necessity of the subdivision of CKD3 in Chin...

    Zhangzhe Peng, Jinwei Wang, Qiongjing Yuan, Xiangcheng Xiao, Hui Xu, Yanyun Xie, Wei Wang, Ling Huang, Yong Zhong, Xiang Ao, Luxia Zhang, Minghui Zhao, Lijian Tao and Qiaoling Zhou

    BMC Nephrology 2017 18:311

    Published on: 13 October 2017

  5. Research article

    Frequency of arrhythmia symptoms and acceptability of implantable cardiac monitors in Hemodialysis patients

    Arrhythmia-related complications and sudden death are common in dialysis patients. However, routine cardiac monitoring has so far not been feasible. Miniaturization of implantable cardiac monitors offers a new...

    Naya El Hage, Bernard G. Jaar, Alan Cheng, Chloe Knight, Elena Blasco-Colmenares, Luis Gimenez, Eliseo Guallar and Tariq Shafi

    BMC Nephrology 2017 18:309

    Published on: 10 October 2017

  6. Correction

    Correction to: Association of plasma potassium with mortality and end-stage kidney disease in patients with chronic kidney disease under nephrologist care - The NephroTest study

    Sandra Wagner, Marie Metzger, Martin Flamant, Pascal Houillier, Jean-Philippe Haymann, François Vrtovsnik, Eric Thervet, Jean-Jacques Boffa, Ziad A. Massy, Bénédicte Stengel and Patrick Rossignol

    BMC Nephrology 2017 18:308

    Published on: 6 October 2017

    The original article was published in BMC Nephrology 2017 18:295

  7. Study protocol

    The effect of regional citrate anti-coagulation on the coagulation system in critically ill patients receiving continuous renal replacement therapy for acute kidney injury - an observational cohort study

    Regional anticoagulation with citrate is the recommended first line treatment for patients receiving continuous renal replacement therapy (CRRT). There is wide variability in filter patency which may be due to...

    Richard Fisher, Katie Lei, Mike J. Mitchell, Gary W. Moore, Helen Dickie, Linda Tovey, Siobhan Crichton and Marlies Ostermann

    BMC Nephrology 2017 18:304

    Published on: 2 October 2017

  8. Research article

    Identification of compound heterozygous patients with primary hyperoxaluria type 1: clinical evaluations and in silico investigations

    Primary hyperoxaluria type 1 (PH1) is an autosomal recessive inherited disorder of glyoxylate metabolism in which excessive oxalates are formed by the liver and excreted by the kidneys. Calcium oxalate crystal...

    Houda Kanoun, Faiçal Jarraya, Bayen Maalej, Amina Lahiani, Hichem Mahfoudh, Fatma Makni, Jamil Hachicha and Faiza Fakhfakh

    BMC Nephrology 2017 18:303

    Published on: 2 October 2017

  9. Research article

    Pathogenic role of glycan-specific IgG antibodies in IgA nephropathy

    Accumulating evidences proved the important roles of circulating IgA1-containing immune complexes (cIgA1) in IgA nephropathy (IgAN). Galactose-deficient IgA1 (Gd-IgA1) and glycan-specific IgG antibody have bee...

    Yan-feng Zhao, Li Zhu, Li-jun Liu, Su-fang Shi, Ji-cheng Lv and Hong Zhang

    BMC Nephrology 2017 18:301

    Published on: 29 September 2017

  10. Research article

    Increased prevalence of renal cysts in patients with sickle cell disease

    Early detection and interventions have enabled patients with sickle cell disease (SCD) to live well into adulthood. Consequently, the chronicity of SCD allows for the insidious manifestation of multisystem com...

    Daveena Meeks, Arunraj Navaratnarajah, Emma Drasar, Ounali Jaffer, C. Jason Wilkins, Swee Lay Thein and Claire C. Sharpe

    BMC Nephrology 2017 18:298

    Published on: 21 September 2017

  11. Study protocol

    Lifestyle intervention to improve quality of life and prevent weight gain after renal transplantation: Design of the Active Care after Transplantation (ACT) randomized controlled trial

    Low physical activity and reduced physical functioning are common after renal transplantation, resulting in a reduced quality of life. Another common post-transplantation complication is poor cardio-metabolic ...

    Gerald Klaassen, Dorien M. Zelle, Gerjan J. Navis, Desie Dijkema, Frederike J. Bemelman, Stephan J.L. Bakker and Eva Corpeleijn

    BMC Nephrology 2017 18:296

    Published on: 15 September 2017

  12. Research article

    Validity and reproducibility of a short food frequency questionnaire among patients with chronic kidney disease

    A balanced diet is essential to slowing the progression of chronic kidney disease (CKD) and managing the symptoms. Currently, no tool is available to easily and quickly assess energy and macronutrient intake i...

    Aurélie Affret, Sandra Wagner, Douae El Fatouhi, Courtney Dow, Emmanuelle Correia, Maryvonne Niravong, Françoise Clavel-Chapelon, Julie De Chefdebien, Denis Fouque, Bénédicte Stengel, Marie-Christine Boutron-Ruault and Guy Fagherazzi

    BMC Nephrology 2017 18:297

    Published on: 15 September 2017

  13. Research article

    Association of plasma potassium with mortality and end-stage kidney disease in patients with chronic kidney disease under nephrologist care - The NephroTest study

    Low and high blood potassium levels are common and were both associated with poor outcomes in patients with chronic kidney disease (CKD). Whether such relationships may be altered in CKD patients receiving opt...

    Sandra Wagner, Marie Metzger, Martin Flamant, Pascal Houillier, Jean-Philippe Haymann, François Vrtovsnik, Eric Thervet, Jean-Jacques Boffa, Ziad A. Massy, Bénédicte Stengel and Patrick Rossignol

    BMC Nephrology 2017 18:295

    Published on: 12 September 2017

    The Correction to this article has been published in BMC Nephrology 2017 18:308

  14. Study protocol

    Efficacy of blood flow restriction exercise during dialysis for end stage kidney disease patients: protocol of a randomised controlled trial

    Exercise during haemodialysis improves strength and physical function. However, both patients and clinicians are time poor, and current exercise recommendations add an excessive time burden making exercise a r...

    Matthew J. Clarkson, Steve F. Fraser, Paul N. Bennett, Lawrence P. McMahon, Catherine Brumby and Stuart A. Warmington

    BMC Nephrology 2017 18:294

    Published on: 11 September 2017

  15. Research article

    Factors associated with foot ulceration and amputation in adults on dialysis: a cross-sectional observational study

    Adults on dialysis are at increased risk of foot ulceration, which commonly precedes more serious lower limb complications, including amputation. Limited data exist regarding the prevalence and factors associa...

    Michelle R. Kaminski, Anita Raspovic, Lawrence P. McMahon, Katrina A. Lambert, Bircan Erbas, Peter F. Mount, Peter G. Kerr and Karl B. Landorf

    BMC Nephrology 2017 18:293

    Published on: 8 September 2017

  16. Research article

    Identification of adenylyl cyclase isoforms mediating parathyroid hormone- and calcitonin-stimulated cyclic AMP accumulation in distal tubule cells

    The distal convoluted tubule (DCT) is an important nephron site for parathyroid hormone (PTH) and calcitonin regulation of urinary divalent cation excretion. These hormones exert their effects on the DCT in su...

    Wararat Kittikulsuth, Peter A. Friedman, Alfred van Hoek, Yang Gao and Donald E. Kohan

    BMC Nephrology 2017 18:292

    Published on: 7 September 2017

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