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  1. Secondary hyperparathyroidism (SHPT) is a common high-risk factor for mortality in end-stage renal disease, and parathyromatosis and supernumerary parathyroid glands are very rare causes of persistent SHPT. Pr...

    Authors: Jun Yang, Jun Zhang, Ning-hu Liu, Hao Liu and Meng-jie Dong

    Citation: BMC Nephrology 2020 21:257

    Content type: Case report

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  2. Renal loss of potassium (K+) and magnesium (Mg2+) in salt losing tubulopathies (SLT) leads to significantly reduced Quality of Life (QoL) and higher risks of cardiac arrhythmia. The normalization of K+ is current...

    Authors: Michael Eder, Elisabeth Darmann, Maria C. Haller, Marija Bojic, Markus Peck-Radosavljevic, Rainer Huditz, Gregor Bond, Andreas Vychytil, Roman Reindl-Schwaighofer and Željko Kikić

    Citation: BMC Nephrology 2020 21:256

    Content type: Research article

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  3. In recent years, the diagnostic utility of urinary protein levels has been demonstrated for the early detection and progression of kidney disease. This study aimed to evaluate the associations of the non-album...

    Authors: Khalid Siddiqui, Salini Scaria Joy, Shaik Sarfaraz Nawaz, Dhekra Alnaqeb, Muhammad Mujammami and Khalid Al-Rubeaan

    Citation: BMC Nephrology 2020 21:255

    Content type: Research article

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  4. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Currie Moore, Lesley-Anne Carter, Sandip Mitra, Suzanne Skevington and Alison Wearden

    Citation: BMC Nephrology 2020 21:254

    Content type: Correction

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    The original article was published in BMC Nephrology 2020 21:185

  5. Angiotensin II type 1 receptors (AT1Rs) are expressed on podocytes, endothelial and other cells, and play an essential role in the maintenance of podocyte function and vascular homeostasis. The presence of AT1...

    Authors: Mohammad Abuzeineh, Amtul Aala, Sami Alasfar and Nada Alachkar

    Citation: BMC Nephrology 2020 21:253

    Content type: Research article

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  6. According to the “lipid nephrotoxicity hypothesis”, there is now significant research being conducted in this area. By studying the role of hyperlipidemia in chronic kidney disease in the general Zhejiang popu...

    Authors: Xudong Liang, Meiyu Ye, Mei Tao, Danna Zheng, Ruyi Cai, Yifan Zhu, Juan Jin and Qiang He

    Citation: BMC Nephrology 2020 21:252

    Content type: Research article

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  7. The occurrences of hyperuricemia and acute kidney injury after antithymocyte globulin treatment are unusual in kidney transplant recipients. Here, we report a unique case of acute kidney injury with extreme hy...

    Authors: Yohan Park, Byung Ha Chung, Cheol Whee Park, Yong-Soo Kim and Chul Woo Yang

    Citation: BMC Nephrology 2020 21:251

    Content type: Case report

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  8. Access to kidney transplantation by uremic children is very limited due to the lack of donors in many countries. We sought to explore small pediatric kidney donors as a strategy to provide transplant opportuni...

    Authors: Xiaojun Su, Wenjun Shang, Longshan Liu, Jun Li, Qian Fu, Yonghua Feng, Huanxi Zhang, Ronghai Deng, Chenglin Wu, Zhigang Wang, Xinlu Pang, Björn Nashan, Guiwen Feng and Changxi Wang

    Citation: BMC Nephrology 2020 21:250

    Content type: Research article

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  9. Renal replacement therapy (RRT) places a burden on patients, and geographical relocation for easier access to healthcare facilities is a necessity for some. Incidence and factors associated with relocation has...

    Authors: Hicham I Cheikh Hassan, Jenny HC Chen and Karumathil Murali

    Citation: BMC Nephrology 2020 21:249

    Content type: Research article

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  10. The 2016 Oxford Classification’s MEST-C scoring system predicts outcomes in adults with IgA nephropathy (IgAN), but it lacks tremendous cohort validation in children with IgAN in China. We sought to verify whe...

    Authors: Heyan Wu, Zhengkun Xia, Chunlin Gao, Pei Zhang, Xiao Yang, Ren Wang, Meiqiu Wang and Yingchao Peng

    Citation: BMC Nephrology 2020 21:247

    Content type: Research article

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  11. Lupus nephritis (LN) is a severe consequence of systemic lupus erythematosus (SLE) that affects approximately 40% of patients. Pathogenic immune complexes that are characteristic of LN deposit in the kidney an...

    Authors: Rachael D. Wright, Fariba Bannerman, Michael W. Beresford and Louise Oni

    Citation: BMC Nephrology 2020 21:245

    Content type: Research article

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  12. Several studies have reported that lower body mass index (BMI) is associated with high mortality in patients with chronic kidney disease (CKD). Rate of infection-related death in CKD patients is increasing. Ho...

    Authors: Tae Yamamoto, Masaaki Nakayama, Mariko Miyazaki, Hiroshi Sato, Masato Matsushima, Toshinobu Sato and Sadayoshi Ito

    Citation: BMC Nephrology 2020 21:244

    Content type: Research article

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  13. To explore the potential value of three-dimensional ultrasonography (3DUS) and contrast-enhanced ultrasound (CEUS) in the diagnosis of diabetic nephropathy (DN) in Chinese diabetic patients with kidney injury.

    Authors: Nan Li, Yi-ru Wang, Xiao-qi Tian, Lin Lin, Shu-yuan Liang, Qiu-yang Li, Xiang Fei, Jie Tang and Yu-kun Luo

    Citation: BMC Nephrology 2020 21:243

    Content type: Research article

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  14. Diabetic kidney disease (DKD) remains one of the leading causes of premature death in diabetes. DKD is classified on albuminuria and reduced kidney function (estimated glomerular filtration rate (eGFR)) but th...

    Authors: Kim M. Gooding, Chrysta Lienczewski, Massimo Papale, Niina Koivuviita, Marlena Maziarz, Anna-Maria Dutius Andersson, Kanishka Sharma, Paola Pontrelli, Alberto Garcia Hernandez, Julie Bailey, Kay Tobin, Virva Saunavaara, Anna Zetterqvist, David Shelley, Irvin Teh, Claire Ball…

    Citation: BMC Nephrology 2020 21:242

    Content type: Study protocol

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  15. Constrictive pericarditis is easily overlooked and can lead to severe problems in hemodynamics and end-organ perfusion, in our patient leading to 98 days of anuria after living kidney transplantation. This was...

    Authors: Caroline Wacker, Michael Weyand, Mario Schiffer and Mirian Opgenoorth

    Citation: BMC Nephrology 2020 21:241

    Content type: Case report

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  16. Preeclampsia (PE) refers to the development of hypertension and new-onset proteinuria or progressive organ damage (especially kidney) in a previously normotensive pregnant women after 20 weeks of gestation. Th...

    Authors: Tomo Suzuki, Daisuke Ichikawa, Mayumi Nakata, Shiika Watanabe, Wei Han, Kaori Kohatsu, Sayuri Shirai, Naohiko Imai, Junki Koike and Yugo Shibagaki

    Citation: BMC Nephrology 2020 21:240

    Content type: Case report

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  17. Dialysis patients have a high pill burden, increasing their care complexity. A previous study in our institution’s dialysis unit found notable discrepancies between medication prescriptions, purchases and pati...

    Authors: Lee Gilad, Yosef S. Haviv, Inbal Cohen-Glickman, David Chinitz and Matan J. Cohen

    Citation: BMC Nephrology 2020 21:239

    Content type: Research article

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  18. This study aimed to ascertain whether the correlation of high serum ferritin with mortality is affected by systemic inflammation and to investigate the optimal serum ferritin level for predicting death when in...

    Authors: Sha Fu, Junzhe Chen, Bo Liu, Peifen Liang, Yuchun Zeng, Min Feng, Zhenjian Xu, Guiqiong Zheng, Suqiong Yang, Anping Xu and Ying Tang

    Citation: BMC Nephrology 2020 21:237

    Content type: Research article

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  19. Atypical hemolytic uremic syndrome (aHUS) is a life-threatening disease that leads to end-stage kidney disease if only a poor response to plasma exchanges (PEs) or eculizumab therapy is achieved.

    Authors: Yusuke Kuroki, Koji Mitsuiki, Kaneyasu Nakagawa, Kazuhiko Tsuruya, Ritsuko Katafuchi, Hideki Hirakata and Toshiaki Nakano

    Citation: BMC Nephrology 2020 21:236

    Content type: Case report

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  20. Sarcoidosis is a multisystem inflammatory disorder and can affect any organ; however, ureteric involvement is extremely rare with only four cases reported in the literature to date, all of which were diagnosed...

    Authors: Michikata Hayashida, Akihiro Yano, Kiichi Hagiwara, Shoichi Nagamoto, Kohei Ogawa, Kazushige Sakaguchi, Naoki Sawa, Toshikazu Okaneya and Shinji Urakami

    Citation: BMC Nephrology 2020 21:235

    Content type: Case report

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  21. Previous studies have not described the relationship between reducing radial artery diameter as well as increasing age and functional maturation of the radio-cephalic arteriovenous fistula (RCAVF) and no data ...

    Authors: Zi-ming Wan, Bo Hu, Qi-quan Lai, Xue-jing Gao, Bo Tu, Yu Zhou and Wen-bo Zhao

    Citation: BMC Nephrology 2020 21:234

    Content type: Research article

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  22. Arteriosclerosis is prevalent in patients with chronic kidney disease (CKD). Our aims were to investigate (1) the effects of 12 months of either balance- or strength- both in combination with endurance trainin...

    Authors: Yunan Zhou, Matthias Hellberg, Thomas Hellmark, Peter Höglund and Naomi Clyne

    Citation: BMC Nephrology 2020 21:233

    Content type: Research article

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  23. There is an increasing burden of non-communicable disease globally. Tenofovir disoproxil fumarate (TDF) is the most commonly prescribed antiretroviral drug globally. Studies show that patients receiving TDF ar...

    Authors: Louis Nyende, Robert Kalyesubula, Emmanuel Sekasanvu and Pauline Byakika-Kibwika

    Citation: BMC Nephrology 2020 21:232

    Content type: Research article

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  24. Haemodialysis patients have a high mortality rate. Part of this can be attributed to vascular access complications. Large retrospective studies have shown a higher mortality in patients dialysed with a cathete...

    Authors: Dieter De Clerck, Florence Bonkain, Wilfried Cools and Patricia Van der Niepen

    Citation: BMC Nephrology 2020 21:231

    Content type: Research article

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  25. Low levels of physical activity are implicated in low life expectancies of people receiving maintenance haemodialysis. Accelerometers are increasingly being used to quantify activity behaviours of this populat...

    Authors: Sean Prescott, Jamie P. Traynor, Ilona Shilliday, Tobia Zanotto, Robert Rush and Thomas H. Mercer

    Citation: BMC Nephrology 2020 21:230

    Content type: Research article

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  26. Proteinuria is a major marker of chronic kidney disease (CKD) progression and the predictor of cardiovascular mortality. The rapid development of renal failure is expected in those patients who have higher lev...

    Authors: Abduzhappar Gaipov, Zhandos Utegulov, Rostislav Bukasov, Duman Turebekov, Pavel Tarlykov, Zhannur Markhametova, Zhangatay Nurekeyev, Zhanar Kunushpayeva and Alisher Sultangaziyev

    Citation: BMC Nephrology 2020 21:229

    Content type: Study protocol

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  27. Although the soluble form of suppression of tumorigenicity 2 (sST2) and soluble low-density lipoprotein receptor relative with 11 ligand-binding repeats (sLR11) have emerged as novel cardiovascular biomarkers ...

    Authors: Yu Bum Choi, Mi Jung Lee, Jung Tak Park, Seung Hyeok Han, Shin-Wook Kang, Tae-Hyun Yoo and Hyung Jong Kim

    Citation: BMC Nephrology 2020 21:228

    Content type: Research article

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  28. Acute kidney injury (AKI) occurs in 12–20% of multiple myeloma (MM) patients. Several studies have shown a reduction of free light chains (FLC) using hemodialysis with High-Cut-Off membranes. However, this tec...

    Authors: M. Victoria Pendón-Ruiz de Mier, Raquel Ojeda, M. Antonia Álvarez-Lara, Ana Navas, Corona Alonso, Javier Caballero-Villarraso, Pedro Aljama, Miguel A. Álvarez, Sagrario Soriano, Mariano Rodríguez and Alejandro Martín-Malo

    Citation: BMC Nephrology 2020 21:227

    Content type: Research article

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  29. Focal segmental glomerulosclerosis (FSGS) causes renal fibrosis and may lead to kidney failure. FSGS and its common complication, proteinuria, are challenging to treat. Corticosteroids are ineffective in many ...

    Authors: Kyle Hayes, Elizabeth Warner, Chris Bollinger, Dale Wright and Richard M. Fitch

    Citation: BMC Nephrology 2020 21:226

    Content type: Research article

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  30. To investigate the metabolite changes in the frontal lobe of the end-stage renal disease (ESRD) patients with depression using proton magnetic resonance spectroscopy (1H-MRS).

    Authors: Jiachen Wang, Tong Zhou, Jihua Liu, Jingjun Shangguan, Xuejun Liu, Zhiming Li, Xiaoming Zhou, Yande Ren and Chengjian Wang

    Citation: BMC Nephrology 2020 21:225

    Content type: Research article

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  31. Idiopathic membranous nephropathy (IMN) is frequently coexisted with diabetes mellitus (DM). Few researches investigate clinical outcomes in IMN patients coexisting diabetes mellitus (DM), including remission ...

    Authors: Zhiyong Xie, Zhilian Li, Wei Dong, Yuanhan Chen, Ruizhao Li, Yanhua Wu, Huaban Liang, Zhiming Ye, Shuangxin Liu, Wei Shi and Xinling Liang

    Citation: BMC Nephrology 2020 21:224

    Content type: Research article

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  32. Acute kidney injury (AKI) is a common postoperative complication of orthotopic liver transplantation (OLT). So far, little attention has been paid on the association between overweight and AKI after OLT, and a...

    Authors: Jian Zhou, Lin Lyu, Lin Zhu, Yongxin Liang, He Dong and Haichen Chu

    Citation: BMC Nephrology 2020 21:223

    Content type: Research article

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  33. Currently very little is known about the perceptions and experiences of kidney transplant recipients from a qualitative perspective. As highlighted by the European Kidney Health Alliance recommendations, provi...

    Authors: C. McKeaveney, H. Noble, A. E. Courtney, P. Gill, S. Griffin, W. Johnston, A. P. Maxwell, F. Teasdale and J. Reid

    Citation: BMC Nephrology 2020 21:222

    Content type: Study protocol

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  34. The association between glomerulonephritis (GN) and cancer has been well known for decades. However, studies evaluating long-term de novo cancer development in patients with GN are limited. This study aimed to...

    Authors: Hyunjin Ryu, Kipyo Kim, Jiwon Ryu, Hyung-Eun Son, Ji-Young Ryu, Sejoong Kim, Ki Young Na, Dong Wan Chae and Ho Jun Chin

    Citation: BMC Nephrology 2020 21:221

    Content type: Research article

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  35. Post-transplant lymphoproliferative disease is a recognized complication following solid organ transplantation. This is usually a B cell disease and frequently associated with Epstein Barr virus infection, alt...

    Authors: Emily K. Glover, R. Alexander Speight, Despina Televantou, Stephanie Needham and Neil S. Sheerin

    Citation: BMC Nephrology 2020 21:220

    Content type: Case report

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  36. Chronic kidney disease (CKD) disrupts mineral homeostasis and its main underlying cause is secondary hyperparathyroidism (SHPT). We previously reported that calcium-sensing receptor (CaSR) mRNA and protein exp...

    Authors: Taketo Uchiyama, Ichiro Ohkido, Akio Nakashima, Yatsumu Saito, Masataka Okabe and Takashi Yokoo

    Citation: BMC Nephrology 2020 21:219

    Content type: Research article

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  37. The extension of the interdialytic interval due to due to dialysis session non-attendance varies according to which session of the week the patient misses. The impact of this on subsequent hospitalization and ...

    Authors: James Fotheringham, Michael T. Smith, Marc Froissart, Florian Kronenberg, Peter Stenvinkel, Jürgen Floege, Kai-Uwe Eckardt and David C. Wheeler

    Citation: BMC Nephrology 2020 21:218

    Content type: Research article

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  38. There are a growing number of studies on ethnic differences in progression and mortality for pre-dialysis chronic kidney disease (CKD), but this literature has yet to be synthesised, particularly for studies o...

    Authors: Hilda O. Hounkpatin, Simon D. S. Fraser, Rory Honney, Gavin Dreyer, Alison Brettle and Paul J. Roderick

    Citation: BMC Nephrology 2020 21:217

    Content type: Research article

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  39. Chronic kidney disease (CKD) affects drug elimination and patients with CKD require appropriate adjustment of renally cleared medications to ensure safe and effective pharmacotherapy. The main objective of thi...

    Authors: Ronald L. Castelino, Timothy Saunder, Alex Kitsos, Gregory M. Peterson, Matthew Jose, Barbara Wimmer, Masuma Khanam, Woldesellassie Bezabhe, Jim Stankovich and Jan Radford

    Citation: BMC Nephrology 2020 21:216

    Content type: Research article

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  40. There is mounting evidence that individuals with kidney disease and kidney stones have an abnormal gut microbiota composition. No studies to date have summarised the evidence to categorise how the gut microbio...

    Authors: Jordan Stanford, Karen Charlton, Anita Stefoska-Needham, Rukayat Ibrahim and Kelly Lambert

    Citation: BMC Nephrology 2020 21:215

    Content type: Research article

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  41. Patients with end-stage renal disease undergoing chronic hemodialysis (HD) are at high risk to develop tuberculosis (TB) associated with a high mortality rate. TB diagnosis is often delayed due to non-specific...

    Authors: Florence Bonkain, Dieter De Clerck, Violette Dirix, Mahavir Singh, Camille Locht, Françoise Mascart and Véronique Corbière

    Citation: BMC Nephrology 2020 21:214

    Content type: Case report

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  42. Older patients with advanced chronic kidney disease often do not understand treatment options for renal replacement therapy, conservative kidney management, and advance care planning. It is unclear whether bot...

    Authors: Nwamaka D. Eneanya, Allison K. Labbe, Taylor L. Stallings, Shananssa Percy, Jennifer S. Temel, Tamar A. Klaiman and Elyse R. Park

    Citation: BMC Nephrology 2020 21:213

    Content type: Research article

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  43. Anaemia is common in haemodialysis (HD) patients and associated with significant morbidity and mortality. Intravenous (IV) iron combined with erythropoiesis-stimulating agents (ESA) is the mainstay treatment o...

    Authors: Jorge A. Jesus-Silva, Archie Lamplugh, Sameera Dhada, James O. Burton and Sunil Bhandari

    Citation: BMC Nephrology 2020 21:212

    Content type: Research article

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  44. Physical inactivity and sedentary behaviour (too much sitting) can contribute to renal dysfunction. However, the potential benefits of behavioural change (e.g. replacing sedentary behaviour with physical activ...

    Authors: Keisei Kosaki, Koichiro Tanahashi, Masahiro Matsui, Nobuhiko Akazawa, Yosuke Osuka, Kiyoji Tanaka, David W. Dunstan, Neville Owen, Ai Shibata, Koichiro Oka and Seiji Maeda

    Citation: BMC Nephrology 2020 21:211

    Content type: Research article

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  45. Blood oxygenation level-dependent magnetic resonance imaging (BOLD-MRI) and diffusion tensor imaging (DTI) are useful methods for investigating the morphology and function of the kidneys, including revealing u...

    Authors: Zhiqiang Wang, Hongxu Liu, Heng Meng and Duo Zhang

    Citation: BMC Nephrology 2020 21:210

    Content type: Research article

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  46. Elevated aspartate aminotransferase/alanine aminotransferase (AST/ALT) ratio is an independent risk factor for cardiovascular disease (CVD) among the general population. However, an association between AST/ALT...

    Authors: Xiaoran Feng, Yueqiang Wen, Fen Fen Peng, Niansong Wang, Xiaojiang Zhan and Xianfeng Wu

    Citation: BMC Nephrology 2020 21:209

    Content type: Research article

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  47. The aim of the present study was to evaluate the association between the histology of active and chronic lesions and urinary protein and serum creatinine (SCr) levels, as common clinical endpoints in clinical ...

    Authors: Eri Katsuyama, Yoshia Miyawaki, Ken-ei Sada, Yosuke Asano, Keigo Hayashi, Yuriko Yamamura, Sumie Hiramatsu-Asano, Michiko Morishita, Keiji Ohashi, Haruki Watanabe, Takayuki Katsuyama, Mariko Narazaki, Yoshinori Matsumoto and Jun Wada

    Citation: BMC Nephrology 2020 21:208

    Content type: Research article

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