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  1. Patients with kidney failure treated with dialysis or kidney transplantation experience difficulties maintaining employment due to the condition itself and the treatment. We aimed to establish the rate of empl...

    Authors: Lilli Kirkeskov, Rasmus K. Carlsen, Thomas Lund and Niels Henrik Buus

    Citation: BMC Nephrology 2021 22:348

    Content type: Research

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  2. Coronary heart disease due to arteriosclerosis is the leading cause of death in type 1 diabetic patients with end-stage renal disease (ESRD). The aim of this study was to evaluate the effect of simultaneous pa...

    Authors: U. G. Lange, S. Rademacher, B. Zirnstein, R. Sucher, K. Semmling, P. Bobbert, A. A. Lederer, D. Buchloh, L. Seidemann, D. Seehofer, N. Jahn and H.-M. Hau

    Citation: BMC Nephrology 2021 22:347

    Content type: Research

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  3. Mycobacteria avium (M. avium) is a species of ubiquitous slowly growing nontuberculous mycobacteria. It causes opportunistic infections. However, M. avium-related peritonitis in peritoneal dialysis (PD) patients ...

    Authors: Jifang Lu, Zhou Jiang, Ling Wang, Shan Mou and Hao Yan

    Citation: BMC Nephrology 2021 22:345

    Content type: Case report

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  4. To describe the long-term hemodialysis arteriovenous fistula (AVF) patency, incidence of AVF use, incidence and nature of AVF complications and surgery in patients after kidney transplantation.

    Authors: Barbara Vajdič Trampuž, Miha Arnol, Jakob Gubenšek, Rafael Ponikvar and Jadranka Buturović Ponikvar

    Citation: BMC Nephrology 2021 22:344

    Content type: Research

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  5. Hyperchloremia is associated with the risks of several morbidities and mortality. However, its relationship with acute kidney injury (AKI) and end-stage renal disease (ESRD) in patients undergoing coronary art...

    Authors: Jae Shin Choi, Donghwan Yun, Dong Ki Kim, Kook-Hwan Oh, Kwon Wook Joo, Yon Su Kim, Ki Young Na and Seung Seok Han

    Citation: BMC Nephrology 2021 22:343

    Content type: Research

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  6. Peritoneal dialysis (PD) can be associated with abnormal cardiac structure and function and increased mortality risk. Therefore, in this study, we analyzed the cardiac structure and function dynamic changes us...

    Authors: Yunyun Zhu, Difei Zhang, Xiaoxuan Hu, Hui Liu, Yuan Xu, Haijing Hou, Yu Peng, Ying Lu, Xusheng Liu and Fuhua Lu

    Citation: BMC Nephrology 2021 22:342

    Content type: Research

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  7. Healthcare costs related to ESRD are well-described, but broader societal costs of ESRD are less known. This study aimed to estimate patient and family costs, including informal care costs and out-of-pocket co...

    Authors: Eline F. de Vries, Jeanine Los, G. Ardine de Wit and Leona Hakkaart - van Roijen

    Citation: BMC Nephrology 2021 22:341

    Content type: Research

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  8. Cardiovascular diseases (CVD) and infections are recognized as serious complications in patients with end stage kidney disease. However, little is known about the change over time in incidence of these complic...

    Authors: Kamal Preet Kaur, Mavish Safdar Chaudry, Emil Loldrup Fosbøl, Lauge Østergaard, Christian Torp-Pedersen and Niels Eske Bruun

    Citation: BMC Nephrology 2021 22:340

    Content type: Research

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  9. The Japanese Society for Dialysis Therapy (JSDT) published in 2013 inaugural hemodialysis (HD) guidelines. Specific targets include 1.4 for single-pool Kt/V (spKt/V) with a minimum dose of 1.2, minimum dialysi...

    Authors: Tadashi Tomo, Maria Larkina, Ayumi Shintani, Tomonari Ogawa, Bruce M. Robinson, Brian Bieber, Lisa Henn and Ronald L. Pisoni

    Citation: BMC Nephrology 2021 22:339

    Content type: Research

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  10. The use of human intravenous immunoglobulin gamma (IVIG) is associated with thromboembolic events as a complication. There are few reported cases of renal infarction during IVIG use in the general population, ...

    Authors: Eun Woo Choi, Jun Young Do, A. Young Kim and Seok Hui Kang

    Citation: BMC Nephrology 2021 22:338

    Content type: Case report

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  11. Hemophagocytic lymphohistiocytosis (HLH) is a rare and life-threatening disease characterized by hyperactivation of the immune system that causes hypercytokinemia and potentially multi organ failure. HLH can o...

    Authors: C. J. Steffen, N. Koch, K. U. Eckardt, K. Amann, E. Seelow and A. Schreiber

    Citation: BMC Nephrology 2021 22:337

    Content type: Case report

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  12. Fluid overload and acute kidney injury are common and associated with poor outcomes among critically ill children. The prodrome of renal angina stratifies patients by risk for severe acute kidney injury, but t...

    Authors: Stephen M. Gorga, Erin F. Carlton, Joseph G. Kohne, Ryan P. Barbaro and Rajit K. Basu

    Citation: BMC Nephrology 2021 22:336

    Content type: Research

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  13. A bundle of preventive measures can be taken to avoid acute kidney injury (AKI) or progression of AKI. We performed a systematic review and meta-analysis to evaluate the compliance to AKI care bundles in hospi...

    Authors: Hannah A. I. Schaubroeck, Diana Vargas, Wim Vandenberghe and Eric A. J. Hoste

    Citation: BMC Nephrology 2021 22:335

    Content type: Research

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  14. Monitoring Health Related Quality of Life (HRQoL) in different stages of chronic kidney disease is advised by all nephrology societies. We aimed to study the relation between quality of life and dialysis adequ...

    Authors: Lamia M. Hasan, Dina A. H. Shaheen, Ghada A. H. El Kannishy, Nagy A. H. Sayed-Ahmed and Ahmed M. Abd El Wahab

    Citation: BMC Nephrology 2021 22:334

    Content type: Research

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  15. The transition from chronic kidney disease stage 5 to initiation of hemodialysis has gained increased attention in recent years as this period is one of high risk for patients with an annual mortality rate exc...

    Authors: Maciej Drozdz, João Frazão, Fatima Silva, Partha Das, Werner Kleophas, Wisam Al Badr, Szymon Brzosko and Stefan H. Jacobson

    Citation: BMC Nephrology 2021 22:333

    Content type: Research article

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  16. Clinical pathways aim to improve patient care. We sought to determine whether an online chronic kidney disease (CKD) clinical pathway was associated with improvements in CKD management.

    Authors: Maoliosa Donald, Michelle D. Smekal, Meghan J. Elliott, Kerry McBrien, Robert G. Weaver, Braden J. Manns, Marcello Tonelli, Aminu Bello, Sharon E. Straus, Nairne Scott-Douglas, Kailash Jindal and Brenda R. Hemmelgarn

    Citation: BMC Nephrology 2021 22:332

    Content type: Research

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  17. Reference intervals (RIs) for clinical chemistry test parameters are specific to the method of measurement and population under service. However, there has been no locally available dry chemistry based RIs for...

    Authors: Goma Kathayat, Daya Ram Pokharel, Naval Kishor Yadav and Manoj Sigdel

    Citation: BMC Nephrology 2021 22:331

    Content type: Research

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  18. It has been shown that individuals with obesity have a higher risk for chronic kidney disease (CKD). However, it is unclear which measure of obesity is most useful for prediction of CKD in the general populati...

    Authors: Ensieh Memarian, Peter M. Nilsson, Isac Zia, Anders Christensson and Gunnar Engström

    Citation: BMC Nephrology 2021 22:330

    Content type: Research

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  19. Fibroblast growth factor23 (FGF23) is elevated in CKD and has been associated with outcomes such as death, cardiovascular (CV) events and progression to Renal Replacement therapy (RRT). The majority of studies...

    Authors: Helen V. Alderson, Rajkumar Chinnadurai, Sara T. Ibrahim, Ozgur Asar, James P. Ritchie, Rachel Middleton, Anders Larsson, Peter J. Diggle, Tobias E. Larsson and Philip A. Kalra

    Citation: BMC Nephrology 2021 22:329

    Content type: Research article

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  20. Some studies have suggested mizoribine (MZR) could inhibit the replication of BK polyomavirus (BKPyV). The purpose of this study was to explore whether conversion from mycophenolate mofetil (MMF) to MZR in the...

    Authors: Ping Li, Dongrui Cheng, Jiqiu Wen, Xuefeng Ni, Kenan Xie, Xue Li and Jinsong Chen

    Citation: BMC Nephrology 2021 22:328

    Content type: Research article

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  21. The vasoconstricting peptide endothelin-1 (ET-1) is associated with endothelial dysfunction. The aim of this paper was to investigate whether circulating ET-1 levels predicts chronic kidney disease (CKD) in a ...

    Authors: Margareta I. Hellgren, Per-Anders Jansson, Hormoz Alayar, Ulf Lindblad and Bledar Daka

    Citation: BMC Nephrology 2021 22:327

    Content type: Research

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  22. Hypertension (HT) is associated with adverse outcomes in kidney transplant (KTX) recipients. Blunting of physiological decrease in nighttime compared to daytime blood pressure (non-dipping status) is frequent ...

    Authors: David A. Jaques, Patrick Saudan, Chantal Martinez, Axel Andres, Pierre-Yves Martin, Antoinette Pechere-Bertschi and Belen Ponte

    Citation: BMC Nephrology 2021 22:325

    Content type: Article

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  23. Chronic kidney disease (CKD) is a common health challenge. There are some risk models predicting CKD adverse outcomes, but seldom focus on the Mongoloid population in East Asian. So, we developed a simple but ...

    Authors: Huizhen Ye, Youyuan Chen, Peiyi Ye, Yu Zhang, Xiaoyi Liu, Guanqing Xiao, Zhe Zhang, Yaozhong Kong and Gehao Liang

    Citation: BMC Nephrology 2021 22:322

    Content type: Research article

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  24. The current study investigated the performance of intravoxel incoherent motion diffusion (IVIM) technology in monitoring early renal injury in streptozotocin rats.

    Authors: You-Zhen Feng, Xiao-Qiao Chen, Zhong-Yuan Cheng, Qi-Ting Lin, Ping-Kang Chen, Ding-Kun Si-Tu, Rui Cao, Long Qian, Baoli Heng and Xiang-Ran Cai

    Citation: BMC Nephrology 2021 22:321

    Content type: Research article

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  25. Focal and segmental glomerulosclerosis (FSGS) is a histologic pattern of injury that characterizes a wide spectrum of diseases. Many genetic causes have been identified in FSGS but even in families with compre...

    Authors: Poornima Vijayan, Saidah Hack, Tony Yao, Mohammad Azfar Qureshi, Andrew D. Paterson, Rohan John, Bernard Davenport, Rachel Lennon, York Pei and Moumita Barua

    Citation: BMC Nephrology 2021 22:320

    Content type: Research article

    Published on:

  26. Progression of renal anemia has been shown to be associated with advanced renal tubulointerstitial lesions. This retrospective study investigated the impact of lower hemoglobin (Hb) levels and renal interstiti...

    Authors: Miho Shimizu, Kengo Furuichi, Shinji Kitajima, Tadashi Toyama, Megumi Oshima, Hisayuki Ogura, Koichi Sato, Shiori Nakagawa, Yuta Yamamura, Taro Miyagawa, Akinori Hara, Yasunori Iwata, Norihiko Sakai, Kiyoki Kitagawa, Mitsuhiro Yoshimura, Hitoshi Yokoyama…

    Citation: BMC Nephrology 2021 22:319

    Content type: Research

    Published on:

  27. People living with chronic kidney disease (CKD) require complex medical management and may be frequently hospitalized. Patient safety incidents during hospitalization can result in serious complications which ...

    Authors: Lucia New, Donna Goodridge, Joanne Kappel, Joshua Lawson, Roy Dobson, Erika Penz, Gary Groot and John Gjevre

    Citation: BMC Nephrology 2021 22:318

    Content type: Research

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  28. HIV subjects have several kidney pathologies, like HIV-associated nephropathy or antiretroviral therapy injury, among others. The global prevalence of Chronic Kidney Disease (CKD) is 8–16%; however, in HIV sub...

    Authors: Verónica Valdivia-Cerda, Monserrat Alvarez-Zavala, Karina Sánchez-Reyes, Rodolfo I. Cabrera-Silva, Vida V. Ruiz-Herrera, Aldo D. Loza-Salazar, Pedro Martínez-Ayala, Juan C. Vázquez-Limón, Guillermo García-García, Jaime F. Andrade-Villanueva and Luz A. González-Hernández

    Citation: BMC Nephrology 2021 22:317

    Content type: Research

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  29. The low-density lipoprotein receptor (LDLR) plays a significant role in maintaining the cellular cholesterol homeostasis. Mutations in the LDLR gene can lead to a significant rise in plasma LDL levels that may re...

    Authors: Monika Buraczynska, Jerry Jacob, Karolina Gwiazda-Tyndel and Andrzej Ksiazek

    Citation: BMC Nephrology 2021 22:316

    Content type: Research

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  30. Medication nonadherence is common among patients with hemodialysis, leading to poorer patient outcomes. Health care professionals have an important role in assessing risk of nonadherence and intervening to sup...

    Authors: Trine Mechta Nielsen, Nina Schjerning, Gudrun Kaldan, Mads Hornum, Bo Feldt-Rasmussen and Thordis Thomsen

    Citation: BMC Nephrology 2021 22:315

    Content type: Research

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  31. SARS-CoV-2 can remain transiently viable on surfaces. We examined if use of shared chairs in outpatient hemodialysis associates with a risk for indirect patient-to-patient transmission of SARS-CoV-2.

    Authors: Ravi Thadhani, Joanna Willetts, Catherine Wang, John Larkin, Hanjie Zhang, Lemuel Rivera Fuentes, Len Usvyat, Kathleen Belmonte, Yuedong Wang, Robert Kossmann, Jeffrey Hymes, Peter Kotanko and Franklin Maddux

    Citation: BMC Nephrology 2021 22:313

    Content type: Research

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  32. Authors: Jan Dudley, Martin Christian, Alice Andrews, Nicola Andrews, Julie Baker, Sheila Boyle, Mairead Convery, Fiona Gamston, Martin Garcia, Shuman Haq, Shivaram Hegde, Richard Holt, Helen Jones, Shakeeb Khan, Jennifer McCaughan, David Milford…

    Citation: BMC Nephrology 2021 22:312

    Content type: Guidelines

    Published on:

  33. Recent studies have shown that the serum uric acid/creatinine ratio (SUA/SCr) is a better predictor of chronic kidney disease (CKD) than serum uric acid (SUA) isolated. The aim of the present study was to eval...

    Authors: Nathalia Rabello Silva, Camila Evangelista Torres Gonçalves, Danilo Lemes Naves Gonçalves, Rosângela Minardi Mitre Cotta and Luciana Saraiva da Silva

    Citation: BMC Nephrology 2021 22:311

    Content type: Research

    Published on:

  34. Post-translational modifications (PTMs) are at the heart of many cellular signaling events, which changes the function of protein. Crotonylation, one of the most important and common PTMs, plays a crucial role...

    Authors: Jiahuang Huang, Donge Tang, Fengping Zheng, Huixuan Xu and Yong Dai

    Citation: BMC Nephrology 2021 22:310

    Content type: Research

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  35. Explore priorities related to outcomes and barriers of adults with chronic kidney disease (CKD) regarding person centred care and care planning.

    Authors: Ype de Jong, Esmee M. van der Willik, Jet Milders, Yvette Meuleman, Rachael L. Morton, Friedo W. Dekker and Merel van Diepen

    Citation: BMC Nephrology 2021 22:309

    Content type: Research

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  36. To prevent infection and thrombosis of central venous catheters (CVCs) in hemodialysis patients, different CVC lock solutions are available. Taurolidine-based solutions and citrate in different concentrations ...

    Authors: Sonja van Roeden, Mathijs van Oevelen, Alferso C. Abrahams, Friedo W. Dekker, Joris I. Rotmans and Sabine C. A. Meijvis

    Citation: BMC Nephrology 2021 22:308

    Content type: Research

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  37. Patients with stage 5 chronic kidney disease (CKD5) collaborate with their clinicians when choosing their future treatment modality. Most elderly patients with CKD5 may only have two treatment options: dialysi...

    Authors: Buur Louise Engelbrecht, Madsen Jens Kristian, Eidemak Inge, Krarup Elizabeth, Lauridsen Thomas Guldager, Taasti Lena Helbo and Finderup Jeanette

    Citation: BMC Nephrology 2021 22:307

    Content type: Research

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  38. Decreased kidney function is commonly caused by hypovolemia. When hypovolemic, the kidney reabsorbs water resulting in concentrated urine. Osmolality is a measure of urine concentration which is more objective...

    Authors: Boonsong K. Kitiwan, Sarinnapha M. Vasunilashorn, Heather J. Baer, Kenneth Mukamal and Stephen P. Juraschek

    Citation: BMC Nephrology 2021 22:306

    Content type: Research

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  39. Albumin is the primary body protein, which can predict the poor prognosis of several critical diseases. However, there are a few scientific studies on the relationship between albumin and the prognosis of dial...

    Authors: Lang Jing Zheng, Weiming Jiang, Lingling Pan and Jingye Pan

    Citation: BMC Nephrology 2021 22:305

    Content type: Research

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  40. Diabetic nephropathy (DN) is one of the most important clinical complications of diabetes mellitus (DM) and is the most common cause of end-stage renal disease. Currently, there is no highly effective medicine...

    Authors: Hua-Bin Guo, Jia-Qing Peng, Xuan Wang, Ke-Kai Zhang, Guang-Zhi Zhong, Wei-Hong Chen and Gui-Xin Shi

    Citation: BMC Nephrology 2021 22:304

    Content type: Research article

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  41. Thymomas have been associated with a broad spectrum of autoimmune diseases. Minimal change disease (MCD) is the most frequent pathological lesion reported. Pathophysiological mechanisms involved in secondary M...

    Authors: Zhour El Ouafi, Clovis Mugnier, Robin Jeannet, Clément Danthu, Marion Duval, Valère Belle Mbou and Fatouma Touré

    Citation: BMC Nephrology 2021 22:303

    Content type: Case report

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  42. Previous studies have shown an association between non-alcoholic fatty liver disease (NAFLD) and chronic kidney disease (CKD), but it is unclear whether the association is independent of metabolic syndrome.

    Authors: Celestin Missikpode, Holly Kramer, Scott J. Cotler, Ramon Durazo-Arvizu, James P. Lash, Eric Kallwitz, Jianwen Cai, Mark H. Kuniholm, Sylvia E. Rosas, Ana C. Ricardo, Gregory A. Talavera, Leopoldo Raij, Amber Pirzada and Martha L. Daviglus

    Citation: BMC Nephrology 2021 22:302

    Content type: Research

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  43. Globally, renal healthcare practitioners provide intensive and protracted support to a highly complex multi-morbid patient population however knowledge about the impact of COVID-19 on these practitioners is ex...

    Authors: Clare Mc Keaveney, Joanne Reid, Claire Carswell, Ann Bonner, Ilaria de Barbieri, William Johnston, Alexander P. Maxwell, Julien O’Riordan, Veronica Strini, Ian Walsh and Helen Noble

    Citation: BMC Nephrology 2021 22:301

    Content type: Research

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  44. Acute kidney injury is a common complication of percutaneous coronary intervention and has been associated with an increased risk of death and progressive chronic kidney disease. However, whether the timing of...

    Authors: Alan S. Go, Thida C. Tan, Rishi V. Parikh, Andrew P. Ambrosy, Leonid V. Pravoverov, Sijie Zheng and Thomas K. Leong

    Citation: BMC Nephrology 2021 22:300

    Content type: Research

    Published on:

  45. We tested the hypotheses that: 1) early exposure to increasing episodes of clinically relevant intermittent hypoxia (IH) is detrimental to the developing kidneys; and 2) there is a critical number of daily IH ...

    Authors: Anano Zangaladze, Charles L. Cai, Matthew Marcelino, Jacob V. Aranda and Kay D. Beharry

    Citation: BMC Nephrology 2021 22:299

    Content type: Research article

    Published on:

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