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  1. Chronic kidney disease (CKD) is a substantial cause of morbidity and mortality worldwide with disproportionate effects in sub-Saharan Africa (SSA). The optimal methods to estimate glomerular filtration rate (G...

    Authors: Robert Kalyesubula, June Fabian, Wisdom Nakanga, Robert Newton, Billy Ssebunnya, Josephine Prynn, Jaya George, Alisha N. Wade, Janet Seeley, Dorothea Nitsch, Christian Hansen, Moffat Nyirenda, Liam Smeeth, Saraladevi Naicker, Amelia C. Crampin and Laurie A. Tomlinson

    Citation: BMC Nephrology 2020 21:20

    Content type: Study protocol

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  2. Acute kidney injury (AKI) is commonly defined using the KDIGO system, which includes criteria based on reduced urine output (UO). There is no consensus on whether UO should be measured using consecutive hourly...

    Authors: Jennifer C. Allen, David S. Gardner, Henry Skinner, Daniel Harvey, Andrew Sharman and Mark A. J. Devonald

    Citation: BMC Nephrology 2020 21:19

    Content type: Research article

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  3. More and more studies demonstrated that genetic variation at C1GALT1 influences Gd-IgA1 level in IgAN. However, whether the expression of β1, 3-galactosyltransferase (β1, 3Gal-T) was influenced may provide ins...

    Authors: Yue Xing, Lina Li, Yaru Zhang, Fanghao Wang, Dandan He, Youxia Liu, Junya Jia, Tiekun Yan and Shan Lin

    Citation: BMC Nephrology 2020 21:18

    Content type: Research article

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  4. End stage kidney disease and hemodialysis dependence are associated with impairments in health-related quality of life (HRQOL), which may be related to vascular access (VA). Few HRQOL measures are VA-specific ...

    Authors: Robert J. Nordyke, Gina Nicholson, Shawn M. Gage, Ted Lithgow, Jonathan Himmelfarb, Matthew B. Rivara, Ron D. Hays, Karen Woo and John Devin Peipert

    Citation: BMC Nephrology 2020 21:16

    Content type: Research article

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  5. Patients with chronic kidney disease are at higher risk of developing cardiovascular disease. Chronic exposure to intermittent hemodialysis may be a source of added stress to the cardiovascular system; intradi...

    Authors: R. Marinovich, Z. Li, T. Tamasi, K. Quinn, S. Wong and C. W. McIntyre

    Citation: BMC Nephrology 2020 21:15

    Content type: Research article

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  6. Eosinophils in kidney disease are poorly understood and are often incidental findings on kidney biopsy. Eosinophilia in blood and renal biopsy tissue is associated with a host of immune and non-immune kidney d...

    Authors: Anam Tariq, Keisuke Okamato, Azka Tariq, Avi Z. Rosenberg, Karim M. Soliman, David W. Ploth, Mohamed G. Atta and Blaithin A. McMahon

    Citation: BMC Nephrology 2020 21:14

    Content type: Research article

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  7. The long-term predictive ability of acute kidney injury (AKI) classification based on “Kidney Disease: Improving Global Outcomes”(KDIGO) AKI diagnosis criteria has not been clinically validated in diffuse prol...

    Authors: Tianxin Chen, Ying Zhou, Jianna Zhang, Chaosheng Chen and Jingye Pan

    Citation: BMC Nephrology 2020 21:13

    Content type: Research article

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  8. Chronic kidney disease (CKD) disease affects gut flora by causing dysbiosis and lead to systemic inflammatory conditions. Here, we provide intestinal flora changes of CKD patients undertook different hemodialy...

    Authors: Jianguang Hu, Xiaoshi Zhong, Jing Yan, Daoyuan Zhou, Danping Qin, Xiao Xiao, Yuanyuan Zheng and Yan Liu

    Citation: BMC Nephrology 2020 21:12

    Content type: Research article

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  9. Due to these changes in kidney function, aging kidneys are more prone to drug-induced impairments in renal properties. Diabetes has been associated with the declined kidney function and an elevated risk of ren...

    Authors: Marjo Heinjoki, Merja Karjalainen, Juha Saltevo, Miia Tiihonen, Maija Haanpää, Hannu Kautiainen and Pekka Mäntyselkä

    Citation: BMC Nephrology 2020 21:11

    Content type: Research article

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  10. Early identification of people with CKD in primary care, particularly those with risk factors such as diabetes and hypertension, enables proactive management and referral to specialist services for progressive...

    Authors: S. A. Hull, V. Rajabzadeh, N. Thomas, S. Hoong, G. Dreyer, H. Rainey and N. Ashman

    Citation: BMC Nephrology 2020 21:10

    Content type: Research article

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  11. The impact of length of hospital stay on activities of daily living (ADLs) has not specifically been investigated among dialysis patients. Therefore, we attempt to verify the association between the length of ...

    Authors: Tsukasa Kamitani, Shingo Fukuma, Sayaka Shimizu, Tadao Akizawa and Shunichi Fukuhara

    Citation: BMC Nephrology 2020 21:9

    Content type: Research article

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  12. Impaired physical function due to muscle weakness and exercise intolerance reduces the ability to perform activities of daily living in patients with end-stage kidney disease, and by consequence, Health-Relate...

    Authors: Karsten Vanden Wyngaert, Amaryllis H. Van Craenenbroeck, Sunny Eloot, Patrick Calders, Bert Celie, Els Holvoet and Wim Van Biesen

    Citation: BMC Nephrology 2020 21:7

    Content type: Research article

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  13. Chronic active antibody-mediated rejection is a major etiology of graft loss in renal transplant recipients. However, there is no consensus on the optimal treatment strategies.

    Authors: Hsien-Fu Chiu, Mei-Chin Wen, Ming-Ju Wu, Cheng-Hsu Chen, Tung-Min Yu, Ya-Wen Chuang, Shih-Ting Huang, Shang-Feng Tsai, Ying-Chih Lo, Hao-Chung Ho and Kuo-Hsiung Shu

    Citation: BMC Nephrology 2020 21:6

    Content type: Research article

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  14. Several factors such as recipient age, BMI, serum cratinine, and positive history of dialysis are important in predicting graft survival among kidney transplant recipients. One factor affecting the transplant ...

    Authors: Gholamhossein Naderi, Amin Azadfar, Seyed Reza Yahyazadeh, Fatemeh Khatami and Seyed Mohammad Kazem Aghamir

    Citation: BMC Nephrology 2020 21:5

    Content type: Research article

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  15. Dialysis patients who miss treatments are twice as likely to visit emergency departments (EDs) compared to adherent patients; however, prospective studies assessing ED use after missed treatments are limited. ...

    Authors: Kamna S. Balhara, Lori Fisher, Naya El Hage, Rosemarie G. Ramos and Bernard G. Jaar

    Citation: BMC Nephrology 2020 21:4

    Content type: Research article

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  16. Dual kidney transplantation (DKT) offers a way to extend the use of kidneys from expanded criteria donors (ECDs). Here, we compared the outcomes of DKT with those of single kidney transplantation from standard...

    Authors: Kyo Won Lee, Jae Berm Park, So Ra Cha, Seo Hee Lee, Young Jae Chung, Heejin Yoo, Kyunga Kim and Sung Joo Kim

    Citation: BMC Nephrology 2020 21:3

    Content type: Research article

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  17. Online haemodiafiltration (OL-HDF) may improve middle molecular clearance in contrast to conventional haemodialysis (HD). However, OL-HDF requires higher convective flows and cannot sufficiently remove large m...

    Authors: Tae Hoon Kim, Seok-hyung Kim, Tae Yeon Kim, Hae Yeul Park, Kwon Soo Jung, Moon Hyoung Lee, Jong Hyun Jhee, Jung Eun Lee, Hoon Young Choi and Hyeong Cheon Park

    Citation: BMC Nephrology 2019 21:2

    Content type: Research article

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  18. Mortality rates associated with acute kidney injury (AKI) vary among critically ill patients. Outcomes are often not corrected for severity or duration of AKI. Our objective was to analyse whether a new variab...

    Authors: Renske Wiersema, Ruben J. Eck, Mikko Haapio, Jacqueline Koeze, Meri Poukkanen, Frederik Keus, Iwan C. C. van der Horst, Ville Pettilä and Suvi T. Vaara

    Citation: BMC Nephrology 2019 21:1

    Content type: Research article

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  19. The risk of acute kidney injury (AKI) attributable to renin angiotensin aldosterone (RAAS) inhibitors and diuretics remains unclear.

    Authors: Jemima Scott, Tim Jones, Maria Theresa Redaniel, Margaret T. May, Yoav Ben-Shlomo and Fergus Caskey

    Citation: BMC Nephrology 2019 20:481

    Content type: Research article

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  20. Patients on home hemodialysis (HHD) exhibit superior survival compared with patients on institutional hemodialysis (IHD) and peritoneal dialysis (PD). There is a sparsity of reports comparing morbidity between...

    Authors: Helena Rydell, Kerstin Ivarsson, Martin Almquist, Naomi Clyne and Mårten Segelmark

    Citation: BMC Nephrology 2019 20:480

    Content type: Research article

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  21. Urinary tract infections (UTI) are the most common of infections after renal transplantation. The consequences of UTIs in this population are serious, with increased morbidity and hospitalisation rates as well...

    Authors: Simon OLENSKI, Carla SCUDERI, Alex CHOO, Aneesha Kaur BHAGAT SINGH, Mandy WAY, Lakshmanan JEYASEELAN and George JOHN

    Citation: BMC Nephrology 2019 20:479

    Content type: Research article

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  22. Administering anti-vascular endothelial growth factor (anti-VEGF) by intraocular injection has been shown to have a safe systemic profile. Nevertheless, incidents of acute kidney injury following anti-VEGF inj...

    Authors: Rachael Ann O’Neill, Patrick Gallagher, Tricia Douglas, Julie-Anne Little, Alexander Peter Maxwell, Giuliana Silvestri and Gareth McKay

    Citation: BMC Nephrology 2019 20:478

    Content type: Research article

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  23. Somatic symptoms are commonly reported by patients on maintenance hemodialysis. Based on evidence that exercise can improve psychological state among the general population, we aimed to evaluate the effects of...

    Authors: Xiaowei Lou, Yiwen Li, Huajuan Shen, Jin Juan and Qiang He

    Citation: BMC Nephrology 2019 20:477

    Content type: Research article

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  24. The commonly used methods for amyloid typing include immunofluorescence or immunohistochemistry (IHC), which sometimes may come with diagnostic pitfalls. Mass spectrometry (MS)-based proteomics has been recogn...

    Authors: Danyang Li, Dan Liu, Hui Xu, Xiao-juan Yu, Fu-de Zhou, Ming-hui Zhao and Su-xia Wang

    Citation: BMC Nephrology 2019 20:476

    Content type: Case report

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  25. Female sex has been reported as an independent predictor of severe post-liver transplantation (LT) chronic kidney disease. We performed a by sex post-hoc analysis of the SURF study, that investigated the preva...

    Authors: Delia Colombo, Alessandro Zullo, Lucia Simoni and Emanuela Zagni

    Citation: BMC Nephrology 2019 20:475

    Content type: Research article

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  26. A recent study has reported that incidence of chronic kidney disease (CKD) is higher in evacuees, but the molecular mechanism still remains unclear. One plausible hypothesis is a change in vascular function fo...

    Authors: Ryosuke Fujii, Hiroya Yamada, Mirai Yamazaki, Eiji Munetsuna, Yoshitaka Ando, Koji Ohashi, Hiroaki Ishikawa, Haruki Shimoda, Kiyomi Sakata, Akira Ogawa, Seiichiro Kobayashi and Koji Suzuki

    Citation: BMC Nephrology 2019 20:474

    Content type: Research article

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  27. Critical limb ischemia (CLI) and intradialytic hypotension (IDH) are common complications in patients on hemodialysis (HD). However, limited data are available on whether IDH is related to CLI in these patient...

    Authors: Ryo Matsuura, Sumi Hidaka, Takayasu Ohtake, Yasuhiro Mochida, Kunihiro Ishioka, Kyoko Maesato, Machiko Oka, Hidekazu Moriya and Shuzo Kobayashi

    Citation: BMC Nephrology 2019 20:473

    Content type: Research article

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  28. Recommended regular saline flushing presents clinical ineffectiveness for hemodialysis (HD) patients at high risk of bleeding with heparin contraindication. Regional citrate anticoagulation (RCA) has previousl...

    Authors: Ting Lin, Li Song, Renwei Huang, Ying Huang, Shuifu Tang, Qizhan Lin, Ying Zhang, Xingbo Wu, Hui Liang, Yuchi Wu, Yuanhan Chen, Huaban Liang, Jianchao Ma, Zhonglin Feng, Zhuo Li, Lixia Xu…

    Citation: BMC Nephrology 2019 20:472

    Content type: Research article

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  29. Poststreptococcal acute glomerulonephritis (PSAGN) in the elderly tends to have a severe clinical course and often presents with crescentic necrotizing glomerulonephritis in the renal biopsy. However, vasculit...

    Authors: Keiko Yano, Hiroyuki Suzuki, Takashi Oda, Yoshihiko Ueda, Tatsuo Tsukamoto and Eri Muso

    Citation: BMC Nephrology 2019 20:471

    Content type: Case report

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  30. A simpler method for detecting atherosclerosis obliterans is required in the clinical setting. Laser Doppler flowmetry (LDF) is easy to perform and can accurately detect deterioration in skin perfusion. We per...

    Authors: Takeo Ishii, Shizuka Takabe, Yuki Yanagawa, Yuko Ohshima, Yasuhiro Kagawa, Atsuko Shibata and Kunio Oyama

    Citation: BMC Nephrology 2019 20:470

    Content type: Research article

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  31. Fabry disease (FD) is an X-linked lysosomal storage disorder caused by mutations of the GLA gene, followed by deficiency in α-galactosidase A (α-gal) activity. Nephrotic syndrome, as the renal phenotype of FD, is...

    Authors: Hironobu Fujisawa, Yosuke Nakayama, Shoichiro Nakao, Ryo Yamamoto, Yuka Kurokawa, Nao Nakamura, Akiko Nagata, Takahiro Tsukimura, Tadayasu Togawa, Hitoshi Sakuraba and Kei Fukami

    Citation: BMC Nephrology 2019 20:469

    Content type: Case report

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  32. Acute kidney injury (AKI) commonly occurs in intensive care units (ICUs), leading to adverse clinical outcomes and increasing costs. However, there are limited epidemiological data of AKI in the critically ill...

    Authors: Li Jiang, Yibing Zhu, Xuying Luo, Ying Wen, Bin Du, Meiping Wang, Zhen Zhao, Yanyan Yin, Bo Zhu and Xiuming Xi

    Citation: BMC Nephrology 2019 20:468

    Content type: Research article

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  33. The goal of this study was to investigate the clinical and pathological features and prognosis of idiopathic membranous nephropathy (IMN) with focal segmental lesions.

    Authors: Jiatong Li, Bing Chen, Caifeng Gao, Jing Huang, Yongmei Wang, Shiyin Zhang, Ying Xu, Wenkai Guo and Rong Wang

    Citation: BMC Nephrology 2019 20:467

    Content type: Research article

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  34. Approximately 30% of patients on dialysis received combination therapy for their phosphate binder prescription; however, few studies for combined effects of phosphate binders are reported. For the purpose of e...

    Authors: Atsushi Yaguchi, Kenji Akahane, Kumi Tsuchioka, Saori Yonekubo, Shota Yamamoto, Yasuaki Tamai, Satoshi Tatemichi and Hiroo Takeda

    Citation: BMC Nephrology 2019 20:465

    Content type: Research article

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  35. Although most cases of tubulointerstitial nephritis in paraproteinemia are monoclonal light chain deposition-mediated, interstitial nephritis as neoplastic interstitial cell infiltration has rarely been descri...

    Authors: Takako Saeki, Takashi Kuroha, Yuya Sato, Maasa Tamura, Akira Iguchi, Tomoyuki Ito, Hajime Yamazaki, Yumi Ito, Kazuhiro Yoshita, Naofumi Imai, Ichiei Narita and Hiroyuki Usuda

    Citation: BMC Nephrology 2019 20:464

    Content type: Case report

    Published on:

  36. Malnutrition and muscle wasting are common in haemodialysis (HD) patients. Their pathogenesis is complex and involves many molecules including Myostatin (Mstn), which acts as a negative regulator of skeletal m...

    Authors: Pasquale Esposito, Yuri Battaglia, Edoardo La Porta, Maria Antonietta Grignano, Elena Caramella, Alessando Avella, Sabrina Peressini, Nicodemo Sessa, Riccardo Albertini, Giuseppe Di Natali, Claudio Lisi, Marilena Gregorini and Teresa Rampino

    Citation: BMC Nephrology 2019 20:462

    Content type: Research article

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  37. Following publication of the original article [1], the authors reported an error in Figs. 3 and S3.

    Authors: Dena E. Cohen, Andrew Lee, Scott Sibbel, Deborah Benner, Steven M. Brunelli and Francesca Tentori

    Citation: BMC Nephrology 2019 20:461

    Content type: Correction

    Published on:

    The original article was published in BMC Nephrology 2019 20:112

  38. C3 glomerulonephritis (C3GN) is a rare disease caused by inherited or acquired complement alternative pathway (CAP) dysregulation, which could also be secondary to monoclonal gammopathy of undetermined signifi...

    Authors: Lin-Lin Li, Zhi-Ying Li, Su-Xia Wang, Xiao-Juan Yu, Ying Tan, Yu Wang, Feng Yu and Ming-Hui Zhao

    Citation: BMC Nephrology 2019 20:459

    Content type: Case report

    Published on:

  39. We aimed to investigate the relationship between the perioperative hemodynamic parameters and the occurrence of cardiac surgery-associated acute kidney injury.

    Authors: Jifu Jin, Jiawei Yu, Su Chi Chang, Jiarui Xu, Sujuan Xu, Wuhua Jiang, Bo Shen, Yamin Zhuang, Chunsheng Wang, Xiaoqiang Ding and Jie Teng

    Citation: BMC Nephrology 2019 20:458

    Content type: Research article

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  40. Ankylosing spondylitis (AS) is a well-known male-predominant inflammatory disease. This study aimed to assess the gender disparity in chronic kidney disease (CKD) in AS patients in China.

    Authors: Wenling Ye, Jing Zhuang, Yang Yu, Hang Li, Xiaomei Leng, Jun Qian, Yan Qin, Limeng Chen and Xue-mei Li

    Citation: BMC Nephrology 2019 20:457

    Content type: Research article

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  41. Despite the obvious survival benefit compared to that among waitlist patients, outcomes of positive crossmatch kidney transplantation (KT) are generally inferior to those of human leukocyte antigen (HLA)-compa...

    Authors: Deok Gie Kim, Juhan Lee, Younhee Park, Myoung Soo Kim, Hyeon Joo Jeong, Soon Il Kim, Yu Seun Kim, Beom Seok Kim and Kyu Ha Huh

    Citation: BMC Nephrology 2019 20:456

    Content type: Research article

    Published on:

  42. The timing of when to initiate dialysis for progressive chronic kidney disease (CKD) patients has not been well established. There has been a strong trend for early dialysis initiation for these patients over ...

    Authors: Xinju Zhao, Pei Wang, Lining Wang, Xiaonong Chen, Wen Huang, Yonghui Mao, Rihong Hu, Xiaohong Cheng, Caili Wang, Li Wang, Ping Zhang, Detian Li, Yuzhu Wang, Wenling Ye, Yuqing Chen, Qiang Jia…

    Citation: BMC Nephrology 2019 20:455

    Content type: Study protocol

    Published on:

  43. Extracellular volume overload is a common problem in peritoneal dialysis (PD) patients and is associated with excessive mortality. We determine the effectiveness of treating PD patients with extracellular volu...

    Authors: Man Ching Law, Bonnie Ching-Ha Kwan, Janny Suk-Fun Fung, Kai Ming Chow, Jack K.C. Ng, Wing-Fai Pang, Phyllis Mei-Shan Cheng, Chi Bon Leung and Cheuk Chun Szeto

    Citation: BMC Nephrology 2019 20:454

    Content type: Research article

    Published on:

  44. The effects of Simultaneous Pancreas Kidney Transplantation (SPKT) on Peripheral Vascular Disease (PVD) warrants additional study and more target focus, since little is known about the mid- and long-term effec...

    Authors: Robert Sucher, Sebastian Rademacher, Nora Jahn, Max Brunotte, Tristan Wagner, Athanasios Alvanos, Elisabeth Sucher, Daniel Seehofer, Uwe Scheuermann and Hans-Michael Hau

    Citation: BMC Nephrology 2019 20:453

    Content type: Research article

    Published on:

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