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  1. Glucocorticoids may impact the accuracy of serum cystatin C (sCysC) in reflecting renal function. We aimed to assess the effect of glucocorticoids on the performance of sCysC in detecting acute kidney injury (...

    Authors: Silin Liang, Mai Shi, Yunpeng Bai, Yujun Deng, Miaoxian Fang, Jiaxin Li, Yijin Wu, Wenying Peng, Yating Hou, Heng Fang, Huidan Zhang and Chunbo Chen

    Citation: BMC Nephrology 2020 21:519

    Content type: Research article

    Published on:

  2. End stage renal disease (ESRD) describes the most severe stage of chronic kidney disease (CKD), when patients need dialysis or renal transplant. There is often a delay in recognizing, diagnosing, and treating ...

    Authors: Zvi Segal, Dan Kalifa, Kira Radinsky, Bar Ehrenberg, Guy Elad, Gal Maor, Maor Lewis, Muhammad Tibi, Liat Korn and Gideon Koren

    Citation: BMC Nephrology 2020 21:518

    Content type: Research article

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  3. Chronic kidney disease (CKD) is characterized by dysbiosis, elevated levels of uremic toxins, systemic inflammation, and increased markers of oxidative stress. These factors lead to an increased risk of cardio...

    Authors: Samuel A. Headley, Donna J. Chapman, Michael J. Germain, Elizabeth E. Evans, Jasmin Hutchinson, Karen L. Madsen, Talat Alp Ikizler, Emily M. Miele, Kristyn Kirton, Elizabeth O’Neill, Allen Cornelius, Brian Martin, Bradley Nindl and Nosratola D. Vaziri

    Citation: BMC Nephrology 2020 21:517

    Content type: Study protocol

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  4. Glomerular disease patients have a high risk of infection, which contributes to the progression of disease per se and mortality, especially in those with long-term use of glucocorticoids and (or) immunosuppres...

    Authors: Yuzhang Han, Zineng Huang, Huifang Zhang, Liyu He, Lin Sun, Yu Liu, Fuyou Liu and Li Xiao

    Citation: BMC Nephrology 2020 21:516

    Content type: Research article

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  5. End-stage renal disease (ESRD) patients are at a substantially higher risk for developing cognitive impairment compared with the healthy population. Dialysis is an essential way to maintain the life of ESRD pa...

    Authors: Shaohui Ma, Ming Zhang, Yang Liu, Dun Ding, Peng Li, Xueying Ma, Hongjuan Liu and Junya Mu

    Citation: BMC Nephrology 2020 21:515

    Content type: Research article

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  6. A renal biopsy is needed to define active inflammatory infiltration and guide therapeutic management in drug-induced acute tubulointerstitial nephritis (D-ATIN). However, factors such as various contraindicati...

    Authors: Xi-zi Zheng, Yang-hui Gu, Tao Su, Xu-jie Zhou, Jun-wen Huang, Ping-ping Sun, Yan Jia, Da-min Xu, Su-xia Wang, Gang Liu and Li Yang

    Citation: BMC Nephrology 2020 21:514

    Content type: Research article

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  7. Reduction in bone mineral density (BMD) measured by dual-energy X-ray absorptiometry (DXA) occurs in secondary hyperparathyroidism associated with chronic kidney disease. BMD generally increases following para...

    Authors: Raymond Lin, Mirna Vucak-Dzumhur and Grahame J. Elder

    Citation: BMC Nephrology 2020 21:513

    Content type: Case report

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  8. In this study, we focused on the role of overhydration (OH) and low serum prealbumin concentration in predicting peritonitis in continuous ambulatory peritoneal dialysis (CAPD) patients over a 3-year period.

    Authors: Quyen Dao Bui Quy, Tuan Pham Ngoc Huy, Loc Nguyen Duc, My Pham Van, Dung Nguyen Huu, Toan Nguyen Duy, Tien Tran Viet, Quyet Do and Thang Le Viet

    Citation: BMC Nephrology 2020 21:512

    Content type: Research article

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  9. Neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) have been reported to be associated with inflammation in end-stage renal disease (ESRD) receiving dialysis. However, the value of NLR...

    Authors: Peiyuan Li, Chenqi Xia, Peng Liu, Zhong Peng, Hong Huang, Juan Wu and Zhangxiu He

    Citation: BMC Nephrology 2020 21:511

    Content type: Research article

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  10. An association of higher levels of β-hydroxybutyrate (β-HB) in serum with greater mortality in hemodialysis (HD) patients has been reported. This study examined the significance of arterial ketone body ratio (...

    Authors: Masaaki Inaba, Yasuro Kumeda, Shinsuke Yamada, Norikazu Toi, Chie Hamai, Koichi Noguchi, Eikichi Yasuda, Yutaka Furumitsu, Masanori Emoto and Yoshiteru Ohno

    Citation: BMC Nephrology 2020 21:510

    Content type: Research article

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  11. Parents’ adaptation affects the health outcomes of children with chronic kidney diseases (CKD). Identifying factors that affect parents’ adaptation is necessary to understand their adaptation status. This stud...

    Authors: Fatemeh Khorsandi, Naser Parizad, Aram Feizi and Masumeh Hemmati MaslakPak

    Citation: BMC Nephrology 2020 21:509

    Content type: Research article

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  12. Increased right ventricular systolic pressure (RVSP), a surrogate marker for pulmonary hypertension, is common in patients with end-stage kidney disease. Limited data suggest improvement of RVSP with intensive...

    Authors: Michael Girsberger and Christopher T. Chan

    Citation: BMC Nephrology 2020 21:508

    Content type: Research article

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  13. Increase in the number of cases in Chronic Kidney Disease of Unknown etiology (CKDu) in Sri Lanka has become a health issue of national concern. Even though, Northern Province is not identified as a high-risk ...

    Authors: Kalaivani Gobalarajah, Prabagar Subramaniam, Uthpala Apekshani Jayawardena, Gobalarajah Rasiah, Sittampalam Rajendra and Jasotha Prabagar

    Citation: BMC Nephrology 2020 21:507

    Content type: Research article

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  14. Hypertension (HTN) is an established risk factor for chronic kidney disease (CKD) and end-stage renal disease (ESRD). Whether sex differences in the effect of HTN on CKD and ESRD incidence exist remains unclea...

    Authors: Misghina Weldegiorgis and Mark Woodward

    Citation: BMC Nephrology 2020 21:506

    Content type: Research article

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  15. Metabolic healthy obesity (MHO), a phenotype of obesity, seems to be associated with a lower risk of cardiovascular disease. However, MHO has a close relationship with a higher incidence of metabolic syndrome ...

    Authors: Shasha Yu, Xiaofan Guo, Guang Xiao Li, Hongmei Yang, Liqiang Zheng and Yingxian Sun

    Citation: BMC Nephrology 2020 21:505

    Content type: Research article

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  16. Since the Coronavirus Disease 2019 (COVID-19) outbreak, there is accumulating data on the clinical characteristics, treatment strategies and prognosis of COVID-19 in patients with concurrent renal disease. Pos...

    Authors: Yi Huang, Xiao-Juan Li, Yue-Qiang Li, Wei Dai, Tiffany Shao, Wei-Yong Liu, Min Han, Gang Xu and Liu Liu

    Citation: BMC Nephrology 2020 21:504

    Content type: Case report

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  17. Endothelial Progenitor Cells have been shown as effective tool in experimental AKI. Several pharmacological strategies for improving EPC-mediated AKI protection were identified in recent years. Aim of the curr...

    Authors: Daniel Patschan, Katrin Schwarze, Björn Tampe, Jan Ulrich Becker, Samy Hakroush, Oliver Ritter, Susann Patschan and Gerhard Anton Müller

    Citation: BMC Nephrology 2020 21:503

    Content type: Research article

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  18. optimal management of end-stage renal disease (ESRD) in hemodialysis (HD) patients should be more studied because it is a serious risk factor for mortality, being considered an unquestionable global priority.

    Authors: Emily de Souza Ferreira, Tiago Ricardo Moreira, Rodrigo Gomes da Silva, Glauce Dias da Costa, Luciana Saraiva da Silva, Samantha Bicalho de Oliveira Cavalier, Beatriz Oliveira Silva, Heloísa Helena Dias, Luiza Delazari Borges, Juliana Costa Machado and Rosângela Minardi Mitre Cotta

    Citation: BMC Nephrology 2020 21:502

    Content type: Research article

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  19. Kidney allograft survival continuously improved with introduction of novel immunosuppressants. However, also immunologically challenging transplants (blood group incompatibility and sensitized recipients) incr...

    Authors: Miriam Good-Weber, Malgorzata Roos, Thomas F. Mueller, Barbara Rüsi and Thomas Fehr

    Citation: BMC Nephrology 2020 21:501

    Content type: Research article

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  20. Home haemodialysis (HHD), has shown improved clinical outcomes, as well as a better quality of life, compared to conventional in-centre haemodialysis (ICHD) but still has a global low prevalence among end-stag...

    Authors: Natalia Target, Cécile Courivaud, Pierre Antoine Michel, Salima Daoud and Michel Thomas

    Citation: BMC Nephrology 2020 21:500

    Content type: Study protocol

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  21. TAFRO syndrome is a clinical subtype of idiopathic multicentric Castleman disease (iMCD) that is characterized by thrombocytopenia, anasarca, fever, reticulin myelofibrosis (or renal dysfunction), and organome...

    Authors: Qianyun Zhou, Yuanyuan Zhang, Guangping Zhou and Jihong Zhu

    Citation: BMC Nephrology 2020 21:499

    Content type: Case report

    Published on:

  23. Haemodialysis can negatively impact quality of life and mental health. Arts-based interventions used successfully in other settings to improve health and well-being, could help address the impact of haemodialy...

    Authors: Claire Carswell, Joanne Reid, Ian Walsh, William Johnston, Helen McAneney, Robert Mullan, Jenny B. Lee, Hugh Nelson, Michael Matthews, Elizabeth Weatherup, Andrea Spencer, Jean Michelo, Anne Quail, Grainne Kielty, Alistair Mackenzie, Jenny Elliott…

    Citation: BMC Nephrology 2020 21:497

    Content type: Research article

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  24. Glomerular involvement in rheumatoid arthritis has been known to be associated with treatment side effects from medications and secondary amyloidosis. However, limited basic science and clinical studies have b...

    Authors: Qiyu Wang, Juan P. Ruiz and Peter D. Hart

    Citation: BMC Nephrology 2020 21:496

    Content type: Case report

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  25. Chronic kidney disease (CKD) is a significant public health concern. In patients with CKD, interventions that support disease self-management have shown to improve health status and quality of life. At the mom...

    Authors: Hongxia Shen, Rianne van der Kleij, Paul J. M. van der Boog, Xiaoyue Song, Wenjiao Wang, Tongtong Zhang, Zhengyan Li, Xiaoping Lou and Niels Chavannes

    Citation: BMC Nephrology 2020 21:495

    Content type: Study protocol

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  26. Chronic kidney disease (CKD), which is characterized by its asymptomatic nature until an end stage, is one of the most common public health problems in the world. Thus, a regular checkup, especially for those ...

    Authors: Meseret Derbew Molla, Maria Degef, Abebe Bekele, Zeleke Geto, Feyissa Challa, Tadesse Lejisa, Tigist Getahun, Meron Sileshi, Yosef Tolcha, Genet Ashebir and Daniel Seifu

    Citation: BMC Nephrology 2020 21:494

    Content type: Research article

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  27. People with chronic kidney disease (CKD) have high levels of co-morbidity and polypharmacy placing them at increased risk of prescribing-related harm. Tools for assessing prescribing safety in the general popu...

    Authors: Fiona Smith, Samantha Hayward, Barnaby Hole, George Kimpton, Christine Sluman, Penny Whiting and Fergus Caskey

    Citation: BMC Nephrology 2020 21:493

    Content type: Research article

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  28. Although young adulthood is associated with transplant loss, many studies do not examine eGFR decline. We aimed to establish clinical risk factors to identify where early intervention might prevent subsequent ...

    Authors: Alexander J. Hamilton, Lucy A. Plumb, Anna Casula and Manish D. Sinha

    Citation: BMC Nephrology 2020 21:492

    Content type: Research article

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  29. Peritoneal dialysis (PD) is a form of therapy for end-stage kidney disease (ESKD), and peritonitis is a known complication. Mycobacterium (M) species associated peritonitis in PD patients is uncommon. Our experie...

    Authors: Anup Singh Jheeta, Jayakeerthi Rangaiah, John Clark, David Makanjuola and Subash Somalanka

    Citation: BMC Nephrology 2020 21:491

    Content type: Case report

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  30. In patients with frequently relapsing nephrotic syndrome, immunosuppressive therapy such as cyclosporine are often required to maintain remission. Cyclosporine has been noted to have tumorgenesis effects. In t...

    Authors: Huai-Chueh Gem Wu, Chao-Neng Cheng, Jiann-Shiuh Chen and Yuan-Yow Chiou

    Citation: BMC Nephrology 2020 21:490

    Content type: Case report

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  31. The link between dietary protein intake and the risk of kidney dysfunction is always a challenging issue. This study aimed to investigate the relationship between total protein, plant protein, and animal prote...

    Authors: Sevda Alvirdizadeh, Emad Yuzbashian, Parvin Mirmiran, Shahryar Eghtesadi and Fereidoun Azizi

    Citation: BMC Nephrology 2020 21:489

    Content type: Research article

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  32. Pregnancy-related Atypical Haemolytic Uremic Syndrome (P-aHUS) is a rare condition affecting genetically predisposed women during pregnancy. It is often difficult to diagnose and has a significant impact on ma...

    Authors: Prianka Puri, Anida Hanxhiu, Daniel V. O’Hara, Danny Hsu and Mirna Vucak-Dzumhur

    Citation: BMC Nephrology 2020 21:488

    Content type: Case report

    Published on:

  34. Critically ill coronavirus disease 2019 (COVID-19) patients have a high risk of acute kidney injury (AKI) that requires renal replacement therapy (RRT). A state of hypercoagulability reduces circuit life spans...

    Authors: Frederic Arnold, Lukas Westermann, Siegbert Rieg, Elke Neumann-Haefelin, Paul Marc Biever, Gerd Walz, Johannes Kalbhenn and Yakup Tanriver

    Citation: BMC Nephrology 2020 21:486

    Content type: Research article

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  35. The purpose of this study was to explore the effect of changing treatment to high-flux hemodialysis (HFHD) on mortality rate in patients with long-term low flux hemodialysis (LFHD).

    Authors: Shuxin Liu, Hong Liu, Zhihong Wang, Lanbo Teng, Cui Dong, Tingting Gui and Yu Zhang

    Citation: BMC Nephrology 2020 21:485

    Content type: Research article

    Published on:

  36. Chronic kidney disease (CKD) is a global public health concern and diabetes is one of the main risk factors for its occurrence and progression. The aim of this research is to determine the prevalence of chroni...

    Authors: Zaher Nazzal, Zakaria Hamdan, Dunia Masri, Oday Abu-Kaf and Mohammad Hamad

    Citation: BMC Nephrology 2020 21:484

    Content type: Research article

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  37. There is concern about the impact of immunosuppressive agents taken by male kidney transplant (KT) recipients on the risk of foetal malformations. The aim of our survey was to estimate the paternity rate and t...

    Authors: Annabel Boyer, Thierry Lobbedez, Mohamed Ouethrani, Angélique Thuillier Lecouf, Nicolas Bouvier, Valérie Châtelet and Bruno Hurault de Ligny

    Citation: BMC Nephrology 2020 21:483

    Content type: Research article

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  38. FGF23 controls serum l,25(OH)2D3 levels and phosphate homeostasis. This study evaluates the effects of ferritin on intact PTH, FGF23, and l,25(OH)2D3 in patients with major thalassemia. It also evaluates FGF23 ch...

    Authors: Forough Saki, Azita Salehifar, Seyed Reza Kassaee and Gholamhossein Ranjbar Omrani

    Citation: BMC Nephrology 2020 21:482

    Content type: Research article

    Published on:

  39. The largest data on the epidemiology of primary glomerular diseases (PGDs) are obtained from the databases of countries or centers. Here, we present the extended results of the Primary Glomerular Diseases Stud...

    Authors: Aydin Turkmen, Abdullah Sumnu, Egemen Cebeci, Halil Yazici, Necmi Eren, Nurhan Seyahi, Kamil Dilek, Fatih Dede, Ulver Derici, Abdulkadir Unsal, Garip Sahin, Murat Sipahioglu, Mahmut Gok, Erhan Tatar, Belda Dursun, Savas Sipahi…

    Citation: BMC Nephrology 2020 21:481

    Content type: Research article

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  40. Hepatitis C virus (HCV) infects more than 71 million people worldwide and chronic HCV infection increases the risk of liver cirrhosis and failure. Haemodialysis (HD) is one of the renal replacement therapies w...

    Authors: Xue Zheng Wong, Chye Chung Gan, Rosmawati Mohamed, Rosnawati Yahya, Shubash Ganapathy, Soek Siam Tan and Soo Kun Lim

    Citation: BMC Nephrology 2020 21:480

    Content type: Research article

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  41. Secondary hyperparathyroidism (SHPT) is a common complication in end-stage renal disease (ESRD) patients, and parathyroidectomy (PTX) is an effective treatment intervention of SHPT. However, the curative impac...

    Authors: Shaohua Chen, Kaixiang Sheng, Ying Shen, Hua Jiang, Xin Lei, Lihui Qu, Chunping Xu, Jianghua Chen and Ping Zhang

    Citation: BMC Nephrology 2020 21:479

    Content type: Research article

    Published on:

  42. Advance Care Planning is recommended for people with end-stage kidney disease but evidence is limited. Robust clinical trials are needed to investigate the impact of advance care planning in this population. T...

    Authors: Peter O’Halloran, Helen Noble, Kelly Norwood, Peter Maxwell, Fliss Murtagh, Joanne Shields, Robert Mullan, Michael Matthews, Christopher Cardwell, Mike Clarke, Rachael Morton, Karan Shah, Trisha Forbes and Kevin Brazil

    Citation: BMC Nephrology 2020 21:478

    Content type: Research article

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  43. Annual decline in kidney function is a widely applied surrogate outcome of renal failure. It is important to understand the relationships between known risk factors and the annual decline in estimated glomerul...

    Authors: Tadashi Toyama, Kiyoki Kitagawa, Megumi Oshima, Shinji Kitajima, Akinori Hara, Yasunori Iwata, Norihiko Sakai, Miho Shimizu, Atsushi Hashiba, Kengo Furuichi and Takashi Wada

    Citation: BMC Nephrology 2020 21:477

    Content type: Research article

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  44. Hypertensive nephropathy (HTN) is a kind of renal injury caused by chronic hypertension, which seriously affect people’s life. The purpose of this study was to identify the potential biomarkers of HTN and unde...

    Authors: Zhen Wang, Zhongjie Liu, Yingxia Yang and Lei Kang

    Citation: BMC Nephrology 2020 21:476

    Content type: Research article

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  45. Aerobic exercise capacity is reduced in non-dialysis chronic kidney disease (CKD), but the magnitude of changes in exercise capacity over time is less known. Our main hypothesis was that aerobic ExCap would de...

    Authors: Helena Wallin, Eva Jansson, Carin Wallquist, Britta Hylander Rössner, Stefan H. Jacobson, Anette Rickenlund and Maria J. Eriksson

    Citation: BMC Nephrology 2020 21:475

    Content type: Research article

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  46. Peritoneal dialysis-associated peritonitis can uncommonly be caused by fungal infections. When they do present, they are associated with significant mortality and morbidity. We describe a case where a sample o...

    Authors: Victoria Jane Carnall, Stephanie Murdock, Cressida Auckland and Christopher J. Mulgrew

    Citation: BMC Nephrology 2020 21:474

    Content type: Case report

    Published on:

  47. As organs infected with Hepatitis C virus (HCV) provide an opportunity to expand the donor pool, the primary aim of this study is to explore patient willingness to accept a kidney from HCV-infected donors comp...

    Authors: Gretchen C. Edwards, Maren E. Shipe, Lindsay Smith, Christianna Gamble, David Shaffer, Beatrice P. Concepcion and Rachel Forbes

    Citation: BMC Nephrology 2020 21:473

    Content type: Research article

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  48. The caregivers of children on peritoneal dialysis face heavy care burdens and may have a high risk of depression. This study aimed to describe the prevalence and severity of depression and identify its related...

    Authors: Rui Zhao, Ying Gu, Xia Shen, Xianying Mai, Cheng Zhou, Yufen Zhang, Yihui Zhai, Qian Shen, Hong Xu and Qing Zhou

    Citation: BMC Nephrology 2020 21:472

    Content type: Research article

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  49. Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) to ALT ratio (AST/ALT ratio) have been shown to be related to non-alcoholic fatty liver disease or insulin resistance, which was associated w...

    Authors: Hirotaka Ochiai, Takako Shirasawa, Takahiko Yoshimoto, Satsue Nagahama, Akihiro Watanabe, Ken Sakamoto and Akatsuki Kokaze

    Citation: BMC Nephrology 2020 21:471

    Content type: Research article

    Published on:

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