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  1. Content type: Research article

    Acute kidney injury (AKI) affects approximately 13% of patients undergoing major abdominal surgery, and is a common and important clinical sign of perioperative injury. The aim of our analysis was to identify ...

    Authors: Ivana Dedinská, Peter Mikolajčík, Patra Skálová, Marián Mokáň and Ľudovít Laca

    Citation: BMC Nephrology 2019 20:272

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  2. Content type: Case report

    Monogenic mutations may be a significant cause of steroid-resistant nephrotic syndrome. NUP93 is a gene previously reported to cause isolated steroid-resistant nephrotic syndrome.

    Authors: Ibrahim Sandokji, Jonathan Marquez, Weizhen Ji, Cynthia A. Zerillo, Monica Konstantino, Saquib A. Lakhani, Mustafa K. Khokha and Jillian K. Warejko

    Citation: BMC Nephrology 2019 20:271

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  3. Content type: Research article

    Despite well-publicized suggestions to utilize arteriovenous fistulae and grafts to initiate hemodialysis, too many patients in the United States start dialysis via central venous catheters despite their well-...

    Authors: Tanya T. Tang, Murray L. Levin, Shubhada N. Ahya, Khaled Boobes and Muhammad H. Hasan

    Citation: BMC Nephrology 2019 20:270

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  4. Content type: Research article

    The product of the concentrations of urinary tissue inhibitor of metalloproteinases-2 and insulin-like growth factor binding protein-7 (urinary [TIMP-2] × [IGFBP-7]) has been suggested as biomarker for early d...

    Authors: Judith Schiefer, Paul Lichtenegger, Gabriela A. Berlakovich, Walter Plöchl, Claus G. Krenn, David M. Baron, Joanna Baron-Stefaniak and Peter Faybik

    Citation: BMC Nephrology 2019 20:269

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  5. Content type: Research article

    Current paradigms of detecting acute kidney injury (AKI) are insensitive and non-specific. Klotho is a pleiotropic protein that is predominantly expressed in renal tubules. In this study, we evaluated the diag...

    Authors: Yingying Qian, Lin Che, Yucheng Yan, Renhua Lu, Mingli Zhu, Song Xue, Zhaohui Ni and Leyi Gu

    Citation: BMC Nephrology 2019 20:268

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  6. Content type: Research article

    CKD has been recognized as risk factors for 25(OH) D deficiency, and Low levels of 25(OH) D have been suggested to be a trigger factor of decreased level of Hb. However, there is lack of information about the ...

    Authors: Shiv Kumar Sah and Laxman Prasad Adhikary

    Citation: BMC Nephrology 2019 20:267

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  7. Content type: Research article

    Sclerostin, an antagonist of the Wingless-type mouse mammary tumor virus integration site (Wnt) pathway that regulates bone metabolism, is a potential contributor of chronic kidney disease (CKD)–mineral and bo...

    Authors: Te-Hui Kuo, Wei-Hung Lin, Jo-Yen Chao, An-Bang Wu, Chin-Chung Tseng, Yu-Tzu Chang, Hung-Hsiang Liou and Ming-Cheng Wang

    Citation: BMC Nephrology 2019 20:266

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  8. Content type: Research article

    Palliative care has improved the quality of end-of-life (EOL) care and lowered the health care cost of cancer, and these benefits should be extended to patients with other serious illnesses including end-stage...

    Authors: Jui-Kun Chiang, Jean-Shi Chen and Yee-Hsin Kao

    Citation: BMC Nephrology 2019 20:265

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  9. Content type: Research article

    Many older patients approaching end-stage kidney disease have to decide whether to go for dialysis or non-dialytic conservative care (CC). Shared decision-making is recommended to align the treatment plan with...

    Authors: Wouter R. Verberne, Wanda S. Konijn, Karen Prantl, Janneke Dijkers, Margriet T. Roskam, Johannes J. M. van Delden and Willem Jan W. Bos

    Citation: BMC Nephrology 2019 20:264

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  10. Content type: Case report

    IgG4-related disease (IgG4-RD) often affects multiple organs and tissues, especially the kidneys, and is characterized by interstitial nephritis, obstructive nephropathy, and in rare cases glomerulopathy (incl...

    Authors: Nan-Nan Zhang, Yan-Yun Wang, Ling-Xin Kong, Wan-Zhong Zou and Bao Dong

    Citation: BMC Nephrology 2019 20:263

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  11. Content type: Research article

    There is limited evidence on the relationship between social support and renal outcomes in African Americans. We sought to determine the association of social support with prevalent chronic kidney disease (CKD...

    Authors: Rasheeda K. Hall, Clemontina A. Davenport, Mario Sims, Cathleen Colón-Emeric, Tiffany Washington, Jennifer St. Clair Russell, Jane Pendergast, Nrupen Bhavsar, Julia Scialla, Crystal C. Tyson, Wei Wang, Yuan-I Min, Bessie Young, L. Ebony Boulware and Clarissa J. Diamantidis

    Citation: BMC Nephrology 2019 20:262

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  12. Content type: Research article

    Epidemiologic studies has shown an association of albuminuria and low estimated glomerular filtration rate (eGFR) with dementia, but the findings are inconsistent. This study examines the association between e...

    Authors: Jessica Mira Gabin, Solfrid Romundstad, Ingvild Saltvedt and Jostein Holmen

    Citation: BMC Nephrology 2019 20:261

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  13. Content type: Research article

    The International Classification of Diseases (ICD) coding system is the industry standard tool for billing, disease classification, and epidemiology purposes. However, ICD codes are often not assigned or incor...

    Authors: Kabir Jalal, Edwin J. Anand, Rocco Venuto, Joe Eberle and Pradeep Arora

    Citation: BMC Nephrology 2019 20:260

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  14. Content type: Research article

    Approximately 30% of Persian cats have a c.10063C > A variant in polycystin 1 (PKD1) homolog causing autosomal dominant polycystic kidney disease (ADPKD). The variant is lethal in utero when in the homozygous sta...

    Authors: Yoshihiko Yu, Kate L. Shumway, Jodi S. Matheson, Marie E. Edwards, Timothy L. Kline and Leslie A. Lyons

    Citation: BMC Nephrology 2019 20:259

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  15. Content type: Research article

    Chronic Kidney Disease - Mineral and Bone Disorder (CKD-MBD) is a significant cause of morbidity among haemodialysis patients and is associated with pathological changes in phosphate, calcium and parathyroid h...

    Authors: Zhipeng Zhan, Brendan Smyth, Nigel D. Toussaint, Nicholas A. Gray, Li Zuo, Janak R. de Zoysa, Christopher T. Chan, Chenggang Jin, Anish Scaria, Carmel M. Hawley, Vlado Perkovic, Meg J. Jardine and Ling Zhang

    Citation: BMC Nephrology 2019 20:258

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  16. Content type: Research article

    Factors associated with left ventricular systolic dysfunction (LVSD) of peritoneal dialysis (PD) patients are limited. We aim to explore and quantify the associated factors of LVSD among PD patients.

    Authors: Teeranan Angkananard, Jirayut Janma, Thanapath Wannasiri, Piyathida Sangthong and Siribha Changsirikulchai

    Citation: BMC Nephrology 2019 20:257

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  17. Content type: Research article

    IgA nephropathy (IgAN) is the commonest global cause of glomerulonephritis. Extent of fibrosis, tubular atrophy and glomerulosclerosis predict renal function decline. Extent of renal fibrosis is assessed with ...

    Authors: M. P. Graham-Brown, A. Singh, J. Wormleighton, N. J. Brunskill, G. P. McCann, J. Barratt, J. O. Burton and G. Xu

    Citation: BMC Nephrology 2019 20:256

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  18. Content type: Research article

    Acute kidney injury (AKI) is the most common extra-pulmonary organ failure in acute respiratory distress syndrome (ARDS). Renal recovery after AKI is determined by several factors. The objective of this study ...

    Authors: Anupol Panitchote, Omar Mehkri, Andrei Hasting, Tarik Hanane, Sevag Demirjian, Heather Torbic, Eduardo Mireles-Cabodevila, Sudhir Krishnan and Abhijit Duggal

    Citation: BMC Nephrology 2019 20:255

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  19. Content type: Research article

    In this study, we investigated the association of time-varying serum albumin levels with mortality over a 5-year period in one cohort of patients undergoing long-term peritoneal dialysis (PD) therapy.

    Authors: Na Hao, Ben-Chung Cheng, Hong-Tao Yang, Chien-Hsing Wu, Yang-Yang Lei, Mei-Chen Chao, Pei-Ying Wang, Li-Chueh Kuo, Sin-Hua Moi, Cheng-Hong Yang and Jin-Bor Chen

    Citation: BMC Nephrology 2019 20:254

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  20. Content type: Research article

    Chronic kidney disease (CKD) is one of the major complications of Human immune deficiency Virus (HIV) and a risk factor for poor outcome of these patients. We aimed to describe the profile and outcome of HIV p...

    Authors: Marie Patrice Halle, Noel Essomba, Hilaire Djantio, Germaine Tsele, Hermine Fouda, Namme Henri Luma, Enow Gloria Ashuntantang and Folefack Francois Kaze

    Citation: BMC Nephrology 2019 20:253

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  21. Content type: Research article

    Observational studies of hemodialysis patients treated thrice weekly have shown that serum and dialysate potassium and bicarbonate concentrations are associated with patient outcomes. The effect of more freque...

    Authors: John K. Leypoldt, Michael A. Kraus, Bertrand L. Jaber, Eric D. Weinhandl and Allan J. Collins

    Citation: BMC Nephrology 2019 20:252

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  22. Content type: Research article

    Acute kidney injury represents a major threat to the transplanted kidney. Nevertheless, these kidneys have the potential to fully recover. Tubular regeneration following acute kidney injury is driven by the re...

    Authors: Daniela Knafl, Wolfgang Winnicki, Peter Mazal and Ludwig Wagner

    Citation: BMC Nephrology 2019 20:251

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  23. Content type: Study protocol

    Globally 10% of the population worldwide are affected by chronic kidney disease (CKD), making it one of the most prevalent chronic diseases. Several studies have highlighted that the symptoms of CKD have a sig...

    Authors: Bushra Alshammari, Helen Noble, Helen McAneney and Peter O’Halloran

    Citation: BMC Nephrology 2019 20:250

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  24. Content type: Research article

    “Acute kidney dysfunction with no rejection” (ADNR) corresponds to acute kidney injury without histological evidence of acute rejection (AR) in kidney transplant recipients (KTR). The prognosis of ADNR is unkn...

    Authors: François Paquot, Laurent Weekers, Catherine Bonvoisin, Hans Pottel and François Jouret

    Citation: BMC Nephrology 2019 20:249

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  25. Content type: Case report

    Thin basement membrane nephropathy (TBMN) is a relatively common disease. Patients typically present with isolated hematuria, which has a good renal prognosis. In contrast, glomerulocystic kidney disease (GCKD...

    Authors: Hiroyuki Hashimoto, Naro Ohashi, Naoko Tsuji, Yoshitaka Naito, Shinsuke Isobe, Tomoyuki Fujikura, Takayuki Tsuji, Akihiko Kato, Kandai Nozu, Kazumoto Iijima and Hideo Yasuda

    Citation: BMC Nephrology 2019 20:248

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  27. Content type: Research article

    Mild cognitive impairment (MCI) occurs frequently in many end stage renal disease (ESRD) patients, may significantly worsen survival odds and prognosis. However, the exact neuropathological mechanisms of MCI c...

    Authors: Haitao Lu, Zhengzhang Gu, Wei Xing, Shanhua Han, Jiangfen Wu, Hua Zhou, Jiule Ding and Jinggang Zhang

    Citation: BMC Nephrology 2019 20:246

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  28. Content type: Research article

    It has been proposed that peroxisome proliferator-activated receptor-γ (PPARγ) agonists might reduce renal fibrosis, however, several studies had contradictory results. Moreover, the possible interaction of TGF-β

    Authors: Ágnes Németh, Miklós M. Mózes, Laurent Calvier, Georg Hansmann and Gábor Kökény

    Citation: BMC Nephrology 2019 20:245

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  29. Content type: Research article

    IgA nephropathy (IgAN) is the most common glomerulonephritis worldwide and is an important cause of end-stage renal disease (ESRD). Exploring novel biomarkers is necessary for predicting the disease activity a...

    Authors: Tong-dan Bi, Jian-nan Zheng, Jun-xiao Zhang, Long-shu Yang, Nan Liu, Li Yao and Lin-lin Liu

    Citation: BMC Nephrology 2019 20:244

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  30. Content type: Research article

    It remained lack of a kind of contrast-induced acute kidney injury (CI-AKI) model which was widely used in clinical practice and comparable to CI-AKI in humans.

    Authors: Yuan-hui Liu, Jin-hua Xue, Deng-xuan Wu, Wei-jie Bei, Kun Wang, Yong Liu, Ji-yan Chen and Ning Tan

    Citation: BMC Nephrology 2019 20:243

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  31. Content type: Research article

    Lab tests on saliva could be useful because of low invasivity. Previous reports indicated that creatinine, uric acid, and potassium are measurable in saliva. For these analytes the study investigated methodolo...

    Authors: Giancarlo Bilancio, Pierpaolo Cavallo, Cinzia Lombardi, Ermanno Guarino, Vincenzo Cozza, Francesco Giordano, Giuseppe Palladino and Massimo Cirillo

    Citation: BMC Nephrology 2019 20:242

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  32. Content type: Research article

    The development of large-scale chronic kidney disease (CKD) cohorts within the Veterans Affairs (VA) system has been limited by several factors, including the high proportion of missing race data etc. The goal...

    Authors: Mukoso N. Ozieh, Mulugeta Gebregziabher, Ralph C. Ward, David J. Taber and Leonard E. Egede

    Citation: BMC Nephrology 2019 20:241

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  33. Content type: Research article

    To evaluate the treatment of sustained low-efficiency hemodialysis (SLED) against patients with multiple organ dysfunction syndrome (MODS) following wasp stings.

    Authors: Ting-Ting Ye, Rong Gou, Ya-Ni Mao, Jian-Ming Shen, Dong He and Yan-Yan Deng

    Citation: BMC Nephrology 2019 20:240

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  34. Content type: Research article

    Majority of children with nephrotic syndrome are steroid sensitive, but treatment of difficult to treat nephrotic (frequent relapsing, steroid dependent and steroid resistant) syndrome is challenging. Low dose...

    Authors: Khemchand Netaram Moorani, Harnam Moolchand Hotchandani, Aasia Mohammad Zubair, Neelesh Chander Lohana and Nanga Ram Veerwani

    Citation: BMC Nephrology 2019 20:239

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  35. Content type: Research article

    Urgent-start peritoneal dialysis (PD) can help patients with end-stage renal diseases (ESRD) that are referred late to dialysis. However, catheter patency and related complications of urgent-start PD have not ...

    Authors: Hongjian Ye, Xiao Yang, Chunyan Yi, Qunying Guo, Yafang Li, Qiongqiong Yang, Wei Chen, Haiping Mao, Jianbo Li, Yagui Qiu, Xunhua Zheng, Dihua Zhang, Jianxiong Lin, Zhijian Li, Zongpei Jiang, Fengxian Huang…

    Citation: BMC Nephrology 2019 20:238

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  36. Content type: Research article

    Body mass index (BMI) is associated with renal disease progression in unspecified CKD. The relationship between BMI and primary glomerular disease (GN) may be more complex. We aimed to evaluate the association...

    Authors: Benjamin M. P. Elyan, Jennifer S. Lees, Keith A. Gillis, Bruce Mackinnon, Jonathan G. Fox, Colin C. Geddes and Emily P. McQuarrie

    Citation: BMC Nephrology 2019 20:237

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  38. Content type: Case report

    For patients with end stage renal disease undergoing hemodialysis, erythrocytosis occurs rarely. Erythrocytosis increases the risk of thrombosis, which is a common complication in hemodialysis patients. The ri...

    Authors: Shree Agrawal, Preethi Ramachandran, Rupinder Gill, Samuel Spitalewitz, Douglas Gunzler, Marcia R. Silver, Edward J. Horwitz and Jeffrey R. Schelling

    Citation: BMC Nephrology 2019 20:235

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  40. Content type: Research article

    Spain has dramatically increased the number of controlled circulatory death donors (cDCD). The initial selection criteria for considering cDCD for kidney transplantation (KT) have been expanded progressively, ...

    Authors: María José Pérez-Sáez, Omar Lafuente Covarrubias, Domingo Hernández, Francesc Moreso, Edoardo Melilli, Javier Juega, Erika de Sousa, Paula López-Sánchez, María Luisa Rodríguez-Ferrero, Naroa Maruri-Kareaga, María Dolores Navarro, Rosalía Valero, María Auxiliadora Mazuecos, Francisco Llamas, Paloma Martín-Moreno, Antón Fernández-García…

    Citation: BMC Nephrology 2019 20:233

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  41. Content type: Research article

    Weight change post-kidney transplantation and its associations in Aboriginal and Torres Strait Islander Australians, a group known to have poor patient and graft outcomes, are unknown. Weight change based on b...

    Authors: Sandawana William Majoni, Shahid Ullah, James Collett, Jaquelyne T. Hughes and Stephen McDonald

    Citation: BMC Nephrology 2019 20:232

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  42. Content type: Research article

    Maintenance dialysis is a costly and resource intense activity. In Australia, inadequate health infrastructure and poor access to technically skilled staff can limit service provision in remote areas where man...

    Authors: G. Gorham, K. Howard, Y. Zhao, A. M. S. Ahmed, P. D. Lawton, C. Sajiv, S. W. Majoni, P. Wood, T. Conlon, S. Signal, S. L. Robinson, S. Brown and A. Cass

    Citation: BMC Nephrology 2019 20:231

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  43. Content type: Study protocol

    Maternal kidney disease (acute kidney injury (AKI), advanced chronic kidney disease (CKD), dependence on dialysis or a kidney transplant) has a substantial impact on pregnancy, with risks of significant perina...

    Authors: Nadom Safi, Elizabeth Sullivan, Zhuoyang Li, Mark Brown, William Hague, Stephen McDonald, Michael J. Peek, Angela Makris, Angela M. O’Brien and Shilpanjali Jesudason

    Citation: BMC Nephrology 2019 20:230

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  44. Content type: Case report

    Acute renal failure is a rare occurrence in a patient with an unremarkable past medical history and should always lead to an in depth clinical study. The occurrence in the same healthy young subject, of consec...

    Authors: V. Esposito, D. Catucci, M. Colucci, M. Torreggiani, F. Grosjean and C. Esposito

    Citation: BMC Nephrology 2019 20:229

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  45. Content type: Research article

    Long-term exposure of mercury may induce glomerulonephritis. Clinical and pathological features of mercury-associated glomerulonephritis are not fully clear. This study retrospectively analyzed 35 cases of mer...

    Authors: Ai-bo Qin, Tao Su, Su-xia Wang, Fan Zhang, Fu-de Zhou and Ming-hui Zhao

    Citation: BMC Nephrology 2019 20:228

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  46. Content type: Research article

    Cystinuria is an inherited disorder of renal amino acid transport that causes recurrent nephrolithiasis and significant morbidity in humans. It has an incidence of 1 in 7000 worldwide making it one of the most...

    Authors: Lauren E. Woodard, Richard C. Welch, Ruth Ann Veach, Thomas M. Beckermann, Feng Sha, Edward J. Weinman, Talat Alp Ikizler, Jay A. Tischfield, Amrik Sahota and Matthew H. Wilson

    Citation: BMC Nephrology 2019 20:227

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  48. Content type: Research article

    Hyperkalaemia occurs frequently in many maintenance haemodialysis (MHD) patients after parathyroidectomy (PTX) with secondary hyperparathyroidism (SHPT). However, the clinical risk factors that predict postope...

    Authors: Yu-Huan Song, Guang-Yan Cai, Yue-Fei Xiao, Yi-Ping Wang, Song-Tao Yang and Xiang-Mei Chen

    Citation: BMC Nephrology 2019 20:225

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  49. Content type: Case report

    Primary hyperoxaluria (PH) is a rare inborn disorder of the metabolism of glyoxylate, which causes the hallmark production oxalate and forms insoluble calcium oxalate crystals that accumulate in the kidney and...

    Authors: Ruiming Cai, Minzhuang Lin, Zhiyong Chen, Yongtong Lai, Xianen Huang, Guozhi Zhao, Xuekun Guo, Zhongtang Xiong, Juan Chen, Hui Chen, Qingping Jiang, Shaoyan Liu, Yuexin Yang, Weixiang Liang, Minhui Zou, Tao Liu…

    Citation: BMC Nephrology 2019 20:224

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  50. Content type: Research article

    Carbon dioxide (CO2) accumulation is a challenging issue in critically ill patients. CO2 can be eliminated by renal replacement therapy but studies are scarce and clinical relevance is unknown. We prospectively s...

    Authors: Joop Jonckheer, Herbert Spapen, Aziz Debain, Joy Demol, Marc Diltoer, Olivier Costa, Katrien Lanckmans, Taku Oshima, Patrick Honoré, Manu Malbrain and Elisabeth De Waele

    Citation: BMC Nephrology 2019 20:222

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