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  1. Research article

    Epidemiology and outcomes of Endophthalmitis in chronic dialysis patients: a 13-year experience in a tertiary referral center in Taiwan

    Endophthalmitis is a severe eye infection leading to disabling outcome. Because there were only a few case report illustrating endophthalmitis in chronic dialysis patient, we would like to investigate the epid...

    George Kuo, Yueh-An Lu, Wei-Chiao Sun, Chao-Yu Chen, Huang-Kai Kao, YuJr Lin, Chia-Hui Lee, Cheng-Chieh Hung, Ya-Chung Tian and Hsiang-Hao Hsu

    BMC Nephrology 2017 18:270

    Published on: 16 August 2017

  2. Research article

    Effect of tolvaptan on renal handling of water and sodium, GFR and central hemodynamics in autosomal dominant polycystic kidney disease during inhibition of the nitric oxide system: a randomized, placebo-controlled, double blind, crossover study

    Tolvaptan slows progression of autosomal dominant polycystic kidney disease (ADPKD) by antagonizing the vasopressin-cAMP axis. Nitric oxide (NO) stimulates natriuresis and diuresis, but its role is unknown dur...

    Safa Al Therwani, My Emma Sofie Malmberg, Jeppe Bakkestroem Rosenbaek, Jesper Noergaard Bech and Erling Bjerregaard Pedersen

    BMC Nephrology 2017 18:268

    Published on: 15 August 2017

  3. Research article

    Diagnostic accuracy of contrast-enhanced ultrasound for characterization of kidney lesions in patients with and without chronic kidney disease

    Patients with chronic kidney disease are at increased risk of cystic kidney disease that requires imaging monitoring in many cases. However, these same patients often have contraindications to contrast-enhance...

    Emily Hueywen Chang, Wui Kheong Chong, Sandeep Kumar Kasoji, Julia Rose Fielding, Ersan Altun, Lee B. Mullin, Jung In Kim, Jason Peter Fine, Paul Alexander Dayton and Wendy Kimryn Rathmell

    BMC Nephrology 2017 18:266

    Published on: 9 August 2017

  4. Research article

    A comparison of early versus late initiation of renal replacement therapy for acute kidney injury in critically ill patients: an updated systematic review and meta-analysis of randomized controlled trials

    To investigate the impact of timing the initiation of renal replacement therapy (RRT) on clinical outcomes in critically ill patients with acute kidney injury (AKI), focusing on the randomized controlled trial...

    Xiao-mei Yang, Guo-wei Tu, Ji-li Zheng, Bo Shen, Guo-guang Ma, Guang-wei Hao, Jian Gao and Zhe Luo

    BMC Nephrology 2017 18:264

    Published on: 7 August 2017

  5. Research article

    Urine neutrophil gelatinase-associated lipocalin to predict renal response after induction therapy in active lupus nephritis

    Tubulointerstitial injury is important to predict the progression of lupus nephritis (LN). Urine neutrophil gelatinase-associated lipocalin (NGAL) has been reported to detect worsening LN disease activity. Thu...

    Bancha Satirapoj, Chagriya Kitiyakara, Asada Leelahavanichkul, Yingyos Avihingsanon and Ouppatham Supasyndh

    BMC Nephrology 2017 18:263

    Published on: 4 August 2017

  6. Case report

    Thrombotic microangiopathy associated with Valproic acid toxicity

    Thrombotic microangiopathy (TMA) is a serious, sometimes life-threatening disorder marked by the presence of endothelial injury and microvascular thrombi. Drug-induced thrombotic microangiopathy (DI-TMA) is on...

    Sean A. Hebert, Timothy P. Bohan, Christian L. Erikson and Rita D. Swinford

    BMC Nephrology 2017 18:262

    Published on: 3 August 2017

  7. Research article

    The impact of IgM deposits on the outcome of Nephrotic syndrome in children

    The significance of IgM deposits in glomerular mesangium has been controversial since they were first described due to the variations in the both the definitions used and described impact on clinical outcome. ...

    Sandra Juozapaite, Rimante Cerkauskiene, Arvydas Laurinavicius and Augustina Jankauskiene

    BMC Nephrology 2017 18:260

    Published on: 3 August 2017

  8. Case report

    Successful treatment of highly advanced immunoglobulin G4-related kidney disease presenting renal mass-like regions with end-stage kidney failure: a case study

    Immunoglobulin G4-related kidney disease characterized by immunoglobulin G4-positive plasma cell-rich tubulointerstitial nephritis has distinctive serological and radiological findings. Renal prognosis is good...

    Hiroyuki Ono, Taichi Murakami, Akira Mima, Eriko Shibata, Masanori Tamaki, Sakiya Yoshimoto, Sayo Ueda, Fumi Kishi, Seiji Kishi, Takashi Kawanaka, Motokazu Matsuura, Kojiro Nagai, Hideharu Abe, Masashi Harada and Toshio Doi

    BMC Nephrology 2017 18:261

    Published on: 3 August 2017

  9. Research article

    Non-steroidal anti-inflammatory drug induced acute kidney injury in the community dwelling general population and people with chronic kidney disease: systematic review and meta-analysis

    Non-steroidal anti-inflammatory drugs (NSAIDs) are a common cause of adverse drug events (ADEs), but renal risks of NSAIDs are less well quantified than gastrointestinal and cardiac risks. This paper reports a...

    Xinyu Zhang, Peter T Donnan, Samira Bell and Bruce Guthrie

    BMC Nephrology 2017 18:256

    Published on: 1 August 2017

  10. Research article

    Prediction of new onset of end stage renal disease in Chinese patients with type 2 diabetes mellitus – a population-based retrospective cohort study

    Since diabetes mellitus (DM) is the leading cause of end stage renal disease (ESRD), this study aimed to develop a 5-year ESRD risk prediction model among Chinese patients with Type 2 DM (T2DM) in primary care.

    Eric Yuk Fai Wan, Daniel Yee Tak Fong, Colman Siu Cheung Fung, Esther Yee Tak Yu, Weng Yee Chin, Anca Ka Chun Chan and Cindy Lo Kuen Lam

    BMC Nephrology 2017 18:257

    Published on: 1 August 2017

  11. Research article

    Predictive factors and prevalence of microalbuminuria in HIV-infected patients: a cross-sectional analysis

    Renal dysfunction is a common problem in the HIV+ population, due to the effect of both the HIV virus and the several classes of ARV drugs such as tenofovir (TDF). It is also known that the presence of renal d...

    Katia Falasca, Marta Di Nicola, Italo Porfilio, Claudio Ucciferri, Elisabetta Schiaroli, Chiara Gabrielli, Daniela Francisci and Jacopo Vecchiet

    BMC Nephrology 2017 18:255

    Published on: 28 July 2017

  12. Research article

    Hemodialysis patients’ preferences for the management of anemia

    Patient engagement in end-stage renal disease (ESRD) is expected to result in a more patient-centered approach to care that aligns with patients’ values, preferences, and goals for treatment. Nevertheless, no ...

    Brett Hauber, John Caloyeras, Joshua Posner, Deborah Brommage, Spiros Tzivelekis and Allan Pollock

    BMC Nephrology 2017 18:253

    Published on: 28 July 2017

  13. Correspondence

    The biobank for the molecular classification of kidney disease: research translation and precision medicine in nephrology

    Advances in technology and the ability to interrogate disease pathogenesis using systems biology approaches are exploding. As exemplified by the substantial progress in the personalized diagnosis and treatment...

    Daniel A. Muruve, Michelle C. Mann, Kevin Chapman, Josee F. Wong, Pietro Ravani, Stacey A. Page and Hallgrimur Benediktsson

    BMC Nephrology 2017 18:252

    Published on: 26 July 2017

  14. Research article

    CD133+ cells are associated with ADIPOCYTOKINES and endothelial dysfunction in hemodialysis patients

    Hemodialysis (HD) patients have increased risk of cardiovascular disease (CVD). Impaired stem cell health and adipocytokine metabolism may play important roles in the complex pathophysiological mechanisms of C...

    Abdullah Ozkok, Riza Atas, Suzan Adin Cinar, Akar Yilmaz, Esin Aktas, Gunnur Deniz and Alaattin Yildiz

    BMC Nephrology 2017 18:250

    Published on: 26 July 2017

  15. Research article

    Indole 3-acetic acid, indoxyl sulfate and paracresyl-sulfate do not influence anemia parameters in hemodialysis patients

    The main reason for anemia in renal failure patients is the insufficient erythropoietin production by the kidneys. Beside erythropoietin deficiency, in vitro studies have incriminated uremic toxins in the path...

    Stanislas Bataille, Marion Pelletier, Marion Sallée, Yvon Berland, Nathalie McKay, Ariane Duval, Stéphanie Gentile, Yosra Mouelhi, Philippe Brunet and Stéphane Burtey

    BMC Nephrology 2017 18:251

    Published on: 26 July 2017

  16. Research article

    Multiple myeloma can be accurately diagnosed in acute kidney injury patients using a rapid serum free light chain test

    Acute kidney injury (AKI) is common in patients with multiple myeloma (MM). Whether serum free light chain (sFLC) measurements can distinguish between myeloma and other causes of AKI requires confirmation to g...

    Jennifer L. J. Heaney, John P. Campbell, Punit Yadav, Ann E. Griffin, Meena Shemar, Jennifer H. Pinney and Mark T. Drayson

    BMC Nephrology 2017 18:247

    Published on: 20 July 2017

  17. Case report

    Beneficial effect of kidney transplantation from a deceased donor on severe chronic refractory intradialytic hypotension – a case report

    Chronic refractory hypotension (IDH, intradialytic hypotension) is a rare but serious problem encountered in patients on hemodialysis. Patients with chronic hypotension are often disqualified by transplant tea...

    Ewa Ignacak, Dominik Cieniawski, Alina Bętkowska-Prokop, Czesław Osuch, Marek Kuźniewski and Władysław Sułowicz

    BMC Nephrology 2017 18:248

    Published on: 20 July 2017

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