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  1. Secondary hyperparathyroidism is a common complication in patients with chronic kidney disease that requires vigilant treatment due to its high mortality rate. Pharmacologic therapy is recommended as an initia...

    Authors: Ho-Ryun Won, Jae Yoon Kang, In Ho Lee, Jin-Man Kim, Jae Won Chang and Bon Seok Koo

    Citation: BMC Nephrology 2019 20:414

    Content type: Case report

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  2. Desmopressin is used to reduce bleeding after kidney biopsy but evidence supporting its use is weak, especially in patients with elevated creatinine. The present study was undertaken to evaluate efficacy of de...

    Authors: Ambarish Athavale, Hemant Kulkarni, Cagil D. Arslan and Peter Hart

    Citation: BMC Nephrology 2019 20:413

    Content type: Research article

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  3. Inflammaging is a persistent, low−grade, sterile, nonresolving inflammatory state, associated with the senescence of the immune system. Such condition downregulates both innate and adaptive immune responses du...

    Authors: Vincenzo Sepe, Marilena Gregorini, Teresa Rampino, Pasquale Esposito, Rosanna Coppo, Francesco Galli and Carmelo Libetta

    Citation: BMC Nephrology 2019 20:412

    Content type: Research article

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  4. Peritoneal fibrosis is the most common complication of peritoneal dialysis, but there is currently no effective treatment. We previously reported that suramin pretreatment prevents the development of peritonea...

    Authors: Chongxiang Xiong, Na Liu, Xiaofei Shao, Sairah Sharif, Hequn Zou and Shougang Zhuang

    Citation: BMC Nephrology 2019 20:411

    Content type: Research article

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  5. IgA nephropathy (IgAN) involves mesangial matrix expansion, but the proteomic composition of this matrix is unknown. The present study aimed to characterize changes in extracellular matrix in IgAN.

    Authors: Flavia Teodora Ioana Paunas, Kenneth Finne, Sabine Leh, Tarig Al-Hadi Osman, Hans-Peter Marti, Frode Berven and Bjørn Egil Vikse

    Citation: BMC Nephrology 2019 20:410

    Content type: Research article

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  6. Delayed graft function (DGF) is an important complication of kidney transplantation and can be diagnosed according to different definitions. DGF has been suggested to be associated with the long-term outcome o...

    Authors: Xiao-jun Hu, Jin Zheng, Yang Li, Xiao-hui Tian, Pu-xun Tian, He-li Xiang, Xiao-ming Pan, Chen-guang Ding, Xiao-ming Ding and Wu-jun Xue

    Citation: BMC Nephrology 2019 20:409

    Content type: Research article

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  7. Nonadherence to medications by patients requiring hemodialysis (HD) leads to unfavorable clinical outcomes. Limited data exist to demonstrate the effect of incorporating patient-centered interventions using co...

    Authors: Sherine Ismail, Abrar Al-Subhi, Eman Youssif, Medhat Ahmed, Abdullah Almalki, Diane L. Seger, Andrew C. Seger and Earl Cook

    Citation: BMC Nephrology 2019 20:408

    Content type: Research article

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  8. Following a substantial increase in the utilization of extracorporeal membrane oxygenation (ECMO) during the last decade, its associated benefits and complications, including acute kidney injury have become mo...

    Authors: Kianoush Kashani and Marlies Ostermann

    Citation: BMC Nephrology 2019 20:404

    Content type: Commentary

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  9. Kidney disease is a serious manifestation of systemic amyloidosis and a major cause of morbidity and mortality. Tuberculosis (TB) occurs up to 27 times more commonly in human immunodeficiency virus (HIV) infec...

    Authors: Muhammed Hassen, William Bates and Mohammed Rafique Moosa

    Citation: BMC Nephrology 2019 20:406

    Content type: Research article

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  10. Persistent hyperparathyroidism after kidney transplantation has been associated with adverse outcomes. Parathyroidectomy is the definitive treatment approach, but the success of parathyroidectomy relies on the...

    Authors: Jun Yang, Jun Zhang, Jian-li Bi, Wan-wen Weng and Meng-jie Dong

    Citation: BMC Nephrology 2019 20:405

    Content type: Case report

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  11. The renal function of the remaining kidney in living donors recovers up to 60~70% of pre-donation estimated-glomerular filtration rate (eGFR) by compensatory hypertrophy. However, the degree of this hypertroph...

    Authors: Sho Nishida, Yuji Hidaka, Mariko Toyoda, Kohei Kinoshita, Kosuke Tanaka, Chiaki Kawabata, Satoshi Hamanoue, Akito Inadome, Hiroshi Yokomizo, Asami Takeda, Soichi Uekihara and Shigeyoshi Yamanaga

    Citation: BMC Nephrology 2019 20:403

    Content type: Research article

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  12. Patients with chronic kidney diseases (CKD) on haemodialysis (HD) have high morbidity and mortality rates, which are also due to the inherent risks associated with nephropathy. Non-adherence (NA) to the differ...

    Authors: Lianna G. G. Dantas, Mário de Seixas Rocha, José Andrade Moura Junior, Edson Luiz Paschoalin, Sandra R. K. P. Paschoalin and Constança M. Sampaio Cruz

    Citation: BMC Nephrology 2019 20:402

    Content type: Research article

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  13. Cystinosis is an autosomal recessive lysosomal storage disorder characterized by accumulation of cystine in lysosomes throughout the body. Cystinosis is caused by mutations in the CTNS gene that encodes the lysos...

    Authors: Svetlana Papizh, Victoria Serzhanova, Alexandra Filatova, Mikhail Skoblov, Vyacheslav Tabakov, Lambert van den Heuvel, Elena Levtchenko and Larisa Prikhodina

    Citation: BMC Nephrology 2019 20:400

    Content type: Case report

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  14. Occurrence of cardiovascular disease (CVD) in the setting of chronic kidney disease (CKD) can be described as a “cruel alliance”, with CVD responsible for about half of all deaths among CKD patients. Chronic k...

    Authors: S. O. Oguntola, M. O. Hassan, R. Duarte, A. Vachiat, P. Manga and S. Naicker

    Citation: BMC Nephrology 2019 20:399

    Content type: Research article

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  15. Patients with chronic kidney disease (CKD) have a high prevalence of cardiovascular diseases, which often lead to physical inactivity that correlates with CKD exacerbation. The benefits of regular exercise to ...

    Authors: Lijun Zhang, Yangyang Wang, Lianlian Xiong, Yanfang Luo, Zhijun Huang and Bin Yi

    Citation: BMC Nephrology 2019 20:398

    Content type: Research article

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  16. Elevated serum phosphorus concentrations are common among maintenance hemodialysis patients. Protein is a major source of dietary phosphate, but restriction of protein intake can result in hypoalbuminemia and ...

    Authors: Kamyar Kalantar-Zadeh, Linda H. Ficociello, Vidhya Parameswaran, Nicolaos V. Athienites, Claudy Mullon, Robert J. Kossmann and Daniel W. Coyne

    Citation: BMC Nephrology 2019 20:396

    Content type: Research article

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  17. Major Depressive Disorder (MDD) can lead to adverse cardiovascular outcomes in patients with chronic kidney disease (CKD). Although one of the proposed mechanisms is heightened platelet activation, effects of ...

    Authors: Nishank Jain, Fei Wan, Monica Kothari, Anuoluwapo Adelodun, Jerry Ware, Ravi Sarode and S. Susan Hedayati

    Citation: BMC Nephrology 2019 20:395

    Content type: Research article

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  18. Sebaceous carcinoma is a rare but progressive malignant skin cancer, and the incidence is approximately five times higher in post-transplant patients than in people who have not received kidney transplants. Se...

    Authors: Masahiro Tomonari, Mariko Shimada, Yasuyuki Nakada, Izumi Yamamoto, Munenari Itoh, Yusuke Koike, Akimitsu Kobayashi, Jun Miki, Hiroki Yamada, Takahiro Kimura, Shinya Saito, Kokichi Sugano, Shigeki Sekine, Hiroyasu Yamamoto, Akihiko Asahina and Takashi Yokoo

    Citation: BMC Nephrology 2019 20:394

    Content type: Case report

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  19. Preliminary studies have shown the potential use of salivary creatinine concentration in the diagnosis of chronic kidney disease (CKD). For saliva to replace serum as a diagnostic tool, studies must be done to...

    Authors: Dada Oluwaseyi Temilola, Karla Bezuidenhout, Rajiv Timothy Erasmus, Lawrence Stephen, Mogamat Razeen Davids and Haly Holmes

    Citation: BMC Nephrology 2019 20:387

    Content type: Research article

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  20. Diabetic nephropathy is a global common cause of chronic kidney disease and end-stage renal disease. A lot of research has been conducted in biomedical sciences, which has enhanced understanding of the pathoph...

    Authors: Eduardo De la Cruz-Cano, Cristina del C. Jiménez-González, Vicente Morales-García, Conny Pineda-Pérez, Juan G. Tejas-Juárez, Francisco J. Rendón-Gandarilla, Silvia Jiménez-Morales and José A. Díaz-Gandarilla

    Citation: BMC Nephrology 2019 20:393

    Content type: Research article

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  21. Online hemodiafiltration (OL-HDF) is associated with better removal of both small and middle molecules and might improve survival compared to conventional hemodialysis (HD). Nevertheless, hemodiafiltration (HD...

    Authors: Charles Cuvelier, Michel Tintillier, Gabriela Migali, Charlotte Van Ende and Jean-Michel Pochet

    Citation: BMC Nephrology 2019 20:392

    Content type: Case report

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  22. Cell-free deoxyribonucleic acid DNA (cf-DNA) in urine is promising due to the advantage of urine as an easily obtained and non-invasive sample source over tissue and blood. In clinical practice, it is importan...

    Authors: Chia-Chu Chang, Ping-Fang Chiu, Chia-Lin Wu, Cheng-Ling Kuo, Ching-Shan Huang, Chin-San Liu and Ching-Hui Huang

    Citation: BMC Nephrology 2019 20:391

    Content type: Research article

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  23. Neuropsychiatric conditions such as depression, delirium and cognitive impairment are common in patients with end-stage kidney disease (ESKD) and individuals suffering from ESKD are more likely to commit suici...

    Authors: Pierre Antoine Brown, Peter O. Magner, Swapnil Hiremath and Edward G. Clark

    Citation: BMC Nephrology 2019 20:390

    Content type: Case report

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  24. Some people who are receiving dialysis treatment have virus infection such as hepatitis B, hepatitis C and/or HIV that is present in their blood. These infections can be transmitted to other patients if blood ...

    Authors: Elizabeth Garthwaite, Veena Reddy, Sam Douthwaite, Simon Lines, Kay Tyerman and James Eccles

    Citation: BMC Nephrology 2019 20:388

    Content type: Guidelines

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  25. Liddle syndrome is a monogenic disease with autosomal dominant inheritance. Basic characteristics of this disease are hypertension, reduced concentration of aldosterone and renin activity, as well as increased...

    Authors: Anastasiya A. Kozina, Tatiana A. Trofimova, Elena G. Okuneva, Natalia V. Baryshnikova, Varvara A. Obuhova, Anna Yu. Krasnenko, Kirill Yu. Tsukanov, Olesya I. Klimchuk, Ekaterina I. Surkova, Peter A. Shatalov and Valery V. Ilinsky

    Citation: BMC Nephrology 2019 20:389

    Content type: Case report

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  26. Patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD) often develop hypertension in childhood or early adulthood. Although this could result in left ventricular hypertrophy (LVH), a major risk fac...

    Authors: Huanwen Chen, Terry Watnick, Susie N. Hong, Barry Daly, Yongfang Li and Stephen L. Seliger

    Citation: BMC Nephrology 2019 20:386

    Content type: Research article

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  27. Conservative management, an approach to treating end-stage kidney disease without dialysis, while generally associated with shorter life expectancy than treatment with dialysis, is associated with fewer hospit...

    Authors: Melissa W. Wachterman, Tarikwa Leveille, Nancy L. Keating, Steven R. Simon, Sushrut S. Waikar and Barbara Bokhour

    Citation: BMC Nephrology 2019 20:385

    Content type: Research article

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  28. Hemorrhagic fever with renal syndrome (HFRS) is an acute disease caused by hantavirus infection and is clinically characterized by fever, various hemorrhagic manifestations and transient renal and hepatic dysf...

    Authors: Li Zhang, Qing-shan Ma, Yan Zhang, Bai-chao Sun and Leng-yue Zhao

    Citation: BMC Nephrology 2019 20:383

    Content type: Case report

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  29. Background: The pathological findings of tonsils in IgA nephropathy include the expansion of T-cell nodules around lymphoid follicles and abnormal reticulation of the crypt epithelium in contrast to chronic to...

    Authors: Takuji Enya, Tomoki Miyazawa, Kohei Miyazaki, Rina Oshima, Yuichi Morimoto, Mitsuru Okada, Tsukasa Takemura and Keisuke Sugimoto

    Citation: BMC Nephrology 2019 20:381

    Content type: Case report

    Published on:

  30. Cancer in patients with chronic kidney disease (CKD) is an added burden to their overall morbidity and mortality. Cancer can be a cause or an effect of CKD. In CKD patients, a better understanding of cancer di...

    Authors: Rajkumar Chinnadurai, Emma Flanagan, Gordon C. Jayson and Philip A. Kalra

    Citation: BMC Nephrology 2019 20:380

    Content type: Research article

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  31. This guideline is written primarily for doctors and nurses working in dialysis units and related areas of medicine in the UK, and is an update of a previous version written in 2009. It aims to provide guidance...

    Authors: Damien Ashby, Natalie Borman, James Burton, Richard Corbett, Andrew Davenport, Ken Farrington, Katey Flowers, James Fotheringham, R. N. Andrea Fox, Gail Franklin, Claire Gardiner, R. N. Martin Gerrish, Sharlene Greenwood, Daljit Hothi, Abdul Khares, Pelagia Koufaki…

    Citation: BMC Nephrology 2019 20:379

    Content type: Guidelines

    Published on:

  32. The burden of kidney diseases is reported to be higher in lower- and middle-income countries as compared to developed countries, and countries in sub-Saharan Africa are reported to be most affected. Health sys...

    Authors: Francis F. Furia, Jacqueline Shoo, Paschal J. Ruggajo, Kajiru Kilonzo, Gopal Basu, Karen Yeates, Santosh Varughese, Einar Svarstad and Onesmo Kisanga

    Citation: BMC Nephrology 2019 20:378

    Content type: Research article

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  33. Lipofuscin deposition is a characteristic manifestation of aging. There is very limited literature in humans and in animals describing these deposits in native kidneys. Overall, it is thought to be non-pathoge...

    Authors: Vivian W. Y. Leung, Sarah-Jeanne Pilon, Pierre O. Fiset and Shaifali Sandal

    Citation: BMC Nephrology 2019 20:376

    Content type: Case report

    Published on:

  34. TAFRO syndrome is a systemic inflammatory disorder that manifests as thrombocytopenia (T), anasarca (A), fever (F), reticulin fibrosis (R), and organomegaly (O). Renal dysfunction is frequently complicated wit...

    Authors: Yoshikuni Nagayama, Mizuki Yamano, Motoka Yagame, Tomoyuki Nariyama, Mikiko Takahashi, Masashi Kawamoto and Katsuyuki Matsui

    Citation: BMC Nephrology 2019 20:375

    Content type: Case report

    Published on:

  35. Heavy metal poisoning can cause debilitating illness if left untreated, and its management in anuric patients poses challenges. Literature with which to guide clinical practice in this area is rather scattered.

    Authors: Chun-Yuan Hsiao, Chip Gresham and Mark R. Marshall

    Citation: BMC Nephrology 2019 20:374

    Content type: Case report

    Published on:

  36. Medication non-adherence is a risk factor for acute kidney transplant rejection. The association of non-adherence with short-term allograft loss in patients who develop acute rejection and are subsequently tre...

    Authors: Ahmed Al-Sheyyab, Laura Binari, Mohammed Shwetar, Everly Ramos, Meghan E. Kapp, Stefanie Bala, Nikita Wilson, Rachel C. Forbes, J. Harold Helderman, Khaled Abdel-Kader and Beatrice P. Concepcion

    Citation: BMC Nephrology 2019 20:373

    Content type: Research article

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  37. Daprodustat is a hypoxia-inducible factor-prolyl hydroxylase inhibitor currently being investigated as a treatment for anemia of chronic kidney disease (CKD) in both dialysis and nondialysis patients. In clini...

    Authors: Christine K. Bailey, Stephen Caltabiano, Alexander R. Cobitz, Chun Huang, Kelly M. Mahar and Vickas V. Patel

    Citation: BMC Nephrology 2019 20:372

    Content type: Research article

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  38. This study was undertaken to compare the accuracy of chronic kidney disease-epidemiology collaboration (eGFRCKD-EPI) to modification of diet in renal disease (eGFRMDRD) and the Cockcroft-Gault formulas of Creatin...

    Authors: Sandro Gelsomino, Massimo Bonacchi, Fabiana Lucà, Fabio Barili, Stefano Del Pace, Orlando Parise, Daniel M. Johnson and Michele Massimo Gulizia

    Citation: BMC Nephrology 2019 20:371

    Content type: Research article

    Published on:

  39. Numerous studies have evaluated the prevalence and importance of mineral and bone disorders among patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD). However, little is known about d...

    Authors: Tianye Yang, Wenji Wang, Xiao Tang, Peng Shi, Lulu Zhang, Wenyan Yu, Yingxin Xie, Daqiao Guo and Feng Ding

    Citation: BMC Nephrology 2019 20:369

    Content type: Research article

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  40. Acute kidney injury (AKI), which may progress to end-stage kidney disease (ESKD), is a potential complication of aortic dissection. Notably, in all reported ESKD cases secondary to aortic dissection, imaging e...

    Authors: Yoshihiro Mukaiyama, Akira Okada, Yutaro Kawakatsu, Satoshi Akuzawa, Kazuchika Suzuki, Naoyuki Ishigami and Tatsuo Yamamoto

    Citation: BMC Nephrology 2019 20:368

    Content type: Case report

    Published on:

  41. Acute kidney injury (AKI) is a common complication in patients undergoing liver transplant (LT) and is associated with high morbidity and mortality. We aim to evaluate the pattern of urine and plasma neutrophi...

    Authors: Camila Lima, Luciana Bertocco de Paiva Haddad, Patrícia Donado Vaz de Melo, Luiz Marcelo Malbouisson, Lilian Pires Freitas do Carmo, Luiz Augusto Carneiro D’Albuquerque and Etienne Macedo

    Citation: BMC Nephrology 2019 20:367

    Content type: Research article

    Published on:

  42. Immune Checkpoint Inhibitors (ICPIs) are promising new drugs in treatment of advanced tumours targeting cytotoxic T-lymphocyte antigen-4 (CTLA-4) and programmed cell death protein-1 (PD1) or its ligand (PDL-1)...

    Authors: Mathilde Lemoine, Baptiste Dilly, Alexandre Curie, Vivien Hébert, Charlotte Laurent, Mélanie Hanoy, Steven Grangé, Dominique Guerrot, Arnaud François and Dominique Bertrand

    Citation: BMC Nephrology 2019 20:366

    Content type: Case report

    Published on:

  43. Kidney transplantation is considered to be the treatment of choice for people with end-stage renal disease (ESRD). However, due to the shortage of available organs and the increase in the ESRD prevalence in Eu...

    Authors: M. Lorent, Y. Foucher, K. Kerleau, S. Brouard, C. Baayen, S. Lebouter, M. Naesens, O. Bestard Matamoros, A. Åsberg and M. Giral

    Citation: BMC Nephrology 2019 20:365

    Content type: Database

    Published on:

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