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  1. Lupus nephropathy (LN) occurs in approximately 50% of patients with systemic lupus erythematosus (SLE), and 20% of them will eventually progress into end-stage renal disease (ESRD). A clinical tool predicting ...

    Authors: Jakub Stojanowski, Andrzej Konieczny, Klaudia Rydzyńska, Izabela Kasenberg, Aleksandra Mikołajczak, Tomasz Gołębiowski, Magdalena Krajewska and Mariusz Kusztal
    Citation: BMC Nephrology 2022 23:381
  2. Changes in renal perfusion may play a pathophysiological role in hypertension and kidney disease, however to date, no method for renal blood flow (RBF) determination in humans has been implemented in clinical ...

    Authors: Stine Sundgaard Langaa, Frank Holden Mose, Claire Anne Fynbo, Jørn Theil and Jesper Nørgaard Bech
    Citation: BMC Nephrology 2022 23:379
  3. Chronic kidney disease (CKD), which affects about 10% of global population, has become a global public health crisis in recent decades. It is well recognized that health information dissemination could change ...

    Authors: Lan Yao, Yubao Li, Qinglou Lian, Junjun Sun, Shuyin Zhao and Pei Wang
    Citation: BMC Nephrology 2022 23:378
  4. The utility of dipstick proteinuria for predicting microalbuminuria in non-diabetic lifestyle-related diseases compared with the urine protein-to-creatinine ratio (uPCR) and the effect of dipstick proteinuria ...

    Authors: Makoto Ogi, Takuya Seto and Yoshinori Wakabayashi
    Citation: BMC Nephrology 2022 23:377
  5. Vascular calcification (VC) is suggested to be associated with serum klotho levels in patients with maintenance hemodialysis (MHD), whereas there is a lack of reports on the associations of VC status in whole ...

    Authors: Yan Lin, Jiayuan Huang, Meiyang Zhou, Cuiping Pan, Aiqin Shan and Canxin Zhou
    Citation: BMC Nephrology 2022 23:374
  6. Anti-glomerular basement membrane (anti-GBM) disease is characterized by crescentic necrotizing glomerulonephritis, with linear deposits of immunoglobulin G (IgG) in the GBM. Classic anti-GBM disease is clinic...

    Authors: Ryo Tamura, Toshiki Doi, Shuma Hirashio, Kensuke Sasaki, Yukinari Masuda, Akira Shimizu and Takao Masaki
    Citation: BMC Nephrology 2022 23:373
  7. A functioning vascular access (VA) is crucial to providing adequate hemodialysis (HD) and considered a critically important outcome by patients and healthcare professionals. A validated, patient-important outc...

    Authors: Andrea K. Viecelli, Armando Teixeira-Pinto, Andrea Valks, Richard Baer, Roy Cherian, Pietro E. Cippà, Jonathan C. Craig, Ranil DeSilva, Allison Jaure, David W. Johnson, Charani Kiriwandeniya, Pascal Kopperschmidt, Wen-J Liu, Timmy Lee, Charmaine Lok, Krishan Madhan…
    Citation: BMC Nephrology 2022 23:372
  8. SARS-CoV-2 viral infection is associated with a rapid and vigorous systemic inflammatory response syndrome. Soluble urokinase-type plasminogen activator receptor (suPAR) is a novel biomarker, both indicative o...

    Authors: Vaidas Vicka, Elija Januskeviciute, Ieva Bartuševiciene, Donata Ringaitiene, Aiste Aleknaviciene, Mindaugas Serpytis, Laurynas Rimsevicius, Marius Miglinas, Ligita Jancoriene and Jurate Sipylaite
    Citation: BMC Nephrology 2022 23:371
  9. Multiple myeloma (MM) is a malignant neoplasm associated with kidney involvement in nearly half of the patients. Cast nephropathy, monoclonal immunoglobulin deposition disease (MIDD), and light chain (AL) amyl...

    Authors: Samantha Innocenti, Beatrice Bacchi, Marco Allinovi, Federico Perfetto, Elisabetta Antonioli, Niccolo’ Marchionni, Carlo Di Mario, Leonardo Caroti, Francesco Cappelli and Pierluigi Stefàno
    Citation: BMC Nephrology 2022 23:370
  10. Acute kidney replacement therapy (KRT) is delivered to acutely ill patients to support organ function and life in the Intensive Care Unit (ICU). Implementing standardized acute KRT pathways can ensure its safe...

    Authors: Dawn Opgenorth, Sean M. Bagshaw, Vincent Lau, Michelle M. Graham, Nancy Fraser, Scott Klarenbach, Louise Morrin, Colleen Norris, Neesh Pannu, Selvi Sinnadurai, Shelley Valaire, Xiaoming Wang and Oleksa G. Rewa
    Citation: BMC Nephrology 2022 23:369
  11. March hemoglobinuria is caused by a hemolytic mechanism due to transient hematuria after physical exercise which, although rare, may lead to acute kidney injury. We report a case of a patient with march hemogl...

    Authors: Maiko Yoshida, Hitoshi Suzuki, Sho Hamaguchi, Masako Iwasaki, Hiromitsu Fukuda, Hisatsugu Takahara, Shigeki Tomita and Yusuke Suzuki
    Citation: BMC Nephrology 2022 23:368
  12. Cytotoxic T lymphocyte antigen-4 (CTLA-4) is an essential inhibitory regulator of immune activation. CTLA-4 haploinsufficiency is known to be associated with dysregulation of FOXP3+ regulatory T cells, hyperactiv...

    Authors: Kaori Kohatsu, Tomo Suzuki, Madoka Takimoto, Katsuomi Matsui, Akinori Hashiguchi, Junki Koike and Sayuri Shirai
    Citation: BMC Nephrology 2022 23:367
  13. IgA nephropathy in children has various clinical manifestations. Kidney biopsy is a gold standard for diagnosis by using Oxford classification 2016 with few studies about the correlation between clinical and p...

    Authors: Karnchanit Sausukpaiboon, Sunee Panombualert, Suwannee Wisanuyotin, Anucha Puapairoj, Piyanan Suparattanagool, Leelawadee Techasatian and Nattakarn Tantawarak
    Citation: BMC Nephrology 2022 23:366
  14. Peritoneal dialysis (PD) is an effective and successful renal replacement therapy. The baseline peritoneal solute transfer rate (PSTR) is related to local membrane inflammation and may be partially genetically...

    Authors: Yue Qian, Li Ding, Liou Cao, Zanzhe Yu, Xinghua Shao, Ling Wang, Minfang Zhang, Qin Wang, Xiajing Che, Na Jiang, Hao Yan, Wei Fang, Yan Jin, Jiaying Huang, Aiping Gu and Zhaohui Ni
    Citation: BMC Nephrology 2022 23:365
  15. Acute kidney injury (AKI) is an under-recognized disorder, which is associated with a high risk for mortality, development of chronic kidney disease (CKD).

    Authors: Teuwafeu Denis Georges, Halle Marie-Patrice, Tonou Sorel Ingrid, Ronald Gobina Mbua, Fouda Menye Hermine and Ashuntantang Gloria
    Citation: BMC Nephrology 2022 23:364
  16. Subjective cognitive complaints refer to self-experienced difficulties with everyday cognitive tasks. Although there has been a fair amount of research on cognitive impairments and cognitive complaints in end-...

    Authors: Frederick H. F. Chan, Stanton Newman, Behram A. Khan and Konstadina Griva
    Citation: BMC Nephrology 2022 23:363
  17. Extended-release calcifediol (ERC), active vitamin D hormones and analogs (AVD) and nutritional vitamin D (NVD) are commonly used therapies for treating secondary hyperparathyroidism (SHPT) in adults with stag...

    Authors: Michael J. Germain, Subir K. Paul, George Fadda, Varshasb Broumand, Andy Nguyen, November H. McGarvey, Matthew D. Gitlin, Charles W. Bishop, Philipp Csomor, Stephen Strugnell and Akhtar Ashfaq
    Citation: BMC Nephrology 2022 23:362
  18. Sun-protective strategies focusing on skin cancer awareness are needed in immunosuppressed patients at risk of skin cancers. The study aims to determine the effect of an integrated skin cancer education progra...

    Authors: Zaw Thet, Alfred King-yin Lam, Shu-Kay Ng, Soe Yu Aung, Thin Han, Dwarakanathan Ranganathan, Stephanie Newsham, Jennifer Borg, Christine Pepito and Tien K. Khoo
    Citation: BMC Nephrology 2022 23:361
  19. Carbapenem-induced neurotoxicity is an unusual side effect, with seizure being the most commonly reported symptom. Among the carbapenems, imipenem-cilastin is classically associated with the most severe neurot...

    Authors: Shamira Shahar, Durga A. Arimuthu and Sadanah Aqashiah Mazlan
    Citation: BMC Nephrology 2022 23:360
  20. Predicting allograft survival is vital for efficient transplant success. With dynamic changes in patient conditions, clinical indicators may change longitudinally, and doctors’ judgments may be highly variable...

    Authors: Baoyi Huang, Mingli Huang, Chengfeng Zhang, Zhiyin Yu, Yawen Hou, Yun Miao and Zheng Chen
    Citation: BMC Nephrology 2022 23:359
  21. Membranoproliferative glomerulonephritis (MPGN), a rare glomerulonephritis that causes nephrotic syndrome in children, is often difficult to treat. Typical immunofluorescence findings include strong C3 stainin...

    Authors: Yuko Hidaka, Hiroshi Tamura, Keishiro Furuie, Shohei Kuraoka, Hiroko Nagata and Hitoshi Nakazato
    Citation: BMC Nephrology 2022 23:358
  22. Subclinical inflammation, including borderline lesions (BL), is very common (30–40%) after kidney transplantation (KT), even in low immunological risk patients, and can lead to interstitial fibrosis/tubular at...

    Authors: Domingo Hernández, Teresa Vázquez-Sánchez, Eugenia Sola, Veronica Lopez, Pedro Ruiz-Esteban, Abelardo Caballero, Eduardo Salido, Myriam Leon, Aurelio Rodriguez, Nuria Serra, Consuelo Rodriguez, Carme Facundo, Manel Perello, Irene Silva, Domingo Marrero-Miranda, Ignacio Cidraque…
    Citation: BMC Nephrology 2022 23:357
  23. To examine the association of the screening frequency of estimated glomerular filtration rate (eGFR) with the substantial reduction in eGFR (≥ 25%) among type 2 diabetes (T2D) patients with normal (eGFR≥60 ml/...

    Authors: Henry Sundqvist, Eveliina Heikkala, Jari Jokelainen, Giuseppina Russo, Ilona Mikkola and Maria Hagnäs
    Citation: BMC Nephrology 2022 23:356
  24. The presence of acute kidney injury (AKI) in pre-eclampsia complicates treatment including; increasing length of hospital stay and a need to access services like dialysis which are largely expensive in resourc...

    Authors: Mariam Hassan, Roland Mayanja, Wasswa G.M Ssalongo, Natumanya Robert, Lugobe Henry Mark, Okello Samson and Rose Muhindo
    Citation: BMC Nephrology 2022 23:353
  25. Hyperkalemia increases the risk of mortality and cardiovascular-related hospitalizations in patients with hemodialysis. Predictors of hyperkalemia are yet to be identified. We aimed at developing a nomogram ab...

    Authors: Ziwei Mei, Jun Chen, Peipei Chen, Songmei Luo, Lie Jin and Limei Zhou
    Citation: BMC Nephrology 2022 23:351
  26. Muscle dysfunction is prevalent in dialysis patients. Gait speed and handgrip strength are simple and reliable methods of assessing muscle function. Numerous observational studies have linked 25-hydroxy vitami...

    Authors: Chen Fu, Fengqin Wu, Fang Chen, Enhong Han, Yuehua Gao and Yongxing Xu
    Citation: BMC Nephrology 2022 23:350
  27. Obesity is a major health problem worldwide and is associated with chronic kidney disease (CKD). Body mass index (BMI) is a common method of diagnosing obesity, but there are concerns about its accuracy and ab...

    Authors: Younghoon Song, Jeong Ah Hwang, Jaeun Shin, Eunjung Cho, Shin Young Ahn, Gang Jee Ko, Young Joo Kwon and Ji Eun Kim
    Citation: BMC Nephrology 2022 23:349
  28. Vascular endothelial growth factor inhibitors (VEGFIs) are used to treat malignant neoplasms and ocular diseases by inhibiting angiogenesis. Systemic use of VEGFIs has various side effects, including hypertens...

    Authors: Yawara Kikuchi, Yoshimi Odashima, Kazuhiro Yoshikawa, Tomoyasu Oda, Fumitaka Tanaka, Hiroki Oikawa, Yasushi Ishigaki and Koichi Asahi
    Citation: BMC Nephrology 2022 23:348
  29. The factors associated with estimated glomerular filtrate rate (eGFR) decline in low risk adults remain relatively unknown. We hypothesized that a polygenic risk score (PRS) will be associated with eGFR decline.

    Authors: Farrukh M. Koraishy, Frank D. Mann, Monika A. Waszczuk, Pei-Fen Kuan, Katherine Jonas, Xiaohua Yang, Anna Docherty, Andrey Shabalin, Sean Clouston, Roman Kotov and Benjamin Luft
    Citation: BMC Nephrology 2022 23:347
  30. There are few studies assessing the quality of life of patients with chronic and end stage kidney disease in sub-Saharan Africa. We aimed to describe the health-related quality of life (HRQOL) of patients unde...

    Authors: Gloria Shumbusho, Celestin Hategeka, Marianne Vidler, Jules Kabahizi and Marla McKnight
    Citation: BMC Nephrology 2022 23:345
  31. Hemodialysis patients are followed by routine laboratory testing. There is uncertainty whether these tests always lead to a change in decision-making. This study aims to discover the number of yearly intervent...

    Authors: Claudia Chidiac, Dania Chelala, Dany Nassar, Chadia Beaini, Hiba Azar, Serge Finianos, Celine Boueri, Jenny Hawi, Ibrahim Abdo and Mabel Aoun
    Citation: BMC Nephrology 2022 23:344
  32. The incidence of end stage kidney disease (ESKD) is increasing in Ghana as with the rest of the world. This study compared the sociodemographic, diagnostic characteristics (clinical, biochemical and imaging) a...

    Authors: Perditer Okyere, Isaac Okyere, Grace Essuman, Joseph Attakora, Dorcas Serwaa, Irene Esi Donkoh and Richard K.D. Ephraim
    Citation: BMC Nephrology 2022 23:343
  33. New lipid-lowering therapy at the start of dialysis and measurement of lipid parameters over the follow-up period is not recommended in dialysis patients, which seems unappropriated in clinical practice. We ai...

    Authors: Xiaoran Feng, Xiaojiang Zhan, Yueqiang Wen, FenFen Peng, Xiaoyang Wang, Niansong Wang, Xianfeng Wu and Junnan Wu
    Citation: BMC Nephrology 2022 23:342
  34. Data on the functional status (FS) of patients on maintenance haemodialysis (MHD) and their caregiver burden (CGB) in SSA where patients have fewer weekly dialysis sessions and pay out-of-pocket for dialysis-r...

    Authors: Alex Tatang Mambap, Innocent Abong Che, Maimouna Mahamat and Gloria Enow Ashuntantang
    Citation: BMC Nephrology 2022 23:341
  35. We developed machine learning models to understand the predictors of shorter-, intermediate-, and longer-term mortality among hemodialysis (HD) patients affected by COVID-19 in four countries in the Americas.

    Authors: Adrián M. Guinsburg, Yue Jiao, María Inés Díaz Bessone, Caitlin K. Monaghan, Beatriz Magalhães, Michael A. Kraus, Peter Kotanko, Jeffrey L. Hymes, Robert J. Kossmann, Juan Carlos Berbessi, Franklin W. Maddux, Len A. Usvyat and John W. Larkin
    Citation: BMC Nephrology 2022 23:340
  36. Prior studies support a genetic basis for postoperative acute kidney injury (AKI). We conducted a genome-wide association study (GWAS), assessed the clinical utility of a polygenic risk score (PRS), and estima...

    Authors: Daniel B. Larach, Adam Lewis, Lisa Bastarache, Anita Pandit, Jing He, Anik Sinha, Nicholas J. Douville, Michael Heung, Michael R. Mathis, Jonathan D. Mosley, Jonathan P. Wanderer, Sachin Kheterpal, Matthew Zawistowski, Chad M. Brummett, Edward D. Siew, Cassianne Robinson-Cohen…
    Citation: BMC Nephrology 2022 23:339
  37. The Tablo® Hemodialysis System (Tablo) is an all in one, easy-to-learn device featuring integrated water purification, on demand dialysate production and two-way wireless data transmission and is approved for ...

    Authors: Tahir Zaman, Kasadi Moore, Jennifer Jellerson, Yaadveer Chahal, Joshua Schumacher, Cynthia Dalessandri-Silva and Michael Aragon
    Citation: BMC Nephrology 2022 23:338
  38. Malnutrition is common in critically ill patients, but nutrition status in critically ill patients with acute kidney injury (AKI) has been poorly studied. Our study aimed to investigate the relationship betwee...

    Authors: Na Wang, Ping Wang, Wen Li, Li Jiang, Meiping Wang, Bo Zhu and Xiuming Xi
    Citation: BMC Nephrology 2022 23:335
  39. Tolvaptan was approved in the United States in 2018 for patients with autosomal dominant polycystic kidney disease (ADPKD) at risk of rapid progression as assessed in a 3-year phase 3 clinical trial (TEMPO 3:4...

    Authors: Gregory Mader, Deirdre Mladsi, Myrlene Sanon, Molly Purser, Christine L. Barnett, Dorothee Oberdhan, Terry Watnick and Stephen Seliger
    Citation: BMC Nephrology 2022 23:334
  40. Immunoglobulin A dominant postinfectious glomerulonephritis (IgA PIGN) is a unique medical entity that is rare in the paediatric population. It usually presents with severe renal failure, heavy proteinuria, hy...

    Authors: A. Saghar, G. Klaus, B. Trutnau, M. Kömhoff, H. J. Gröne and S. Weber
    Citation: BMC Nephrology 2022 23:333
  41. Patients who need a live donor kidney transplant (LDKT) must often ask potential donors (PLDs) themselves. This is a difficult task and healthcare could unburden them by making this first contact, ensuring als...

    Authors: Eva Lagging, Kjerstin Larsson, Jonas Wadström, Linda Gyllström Krekula and Annika Tibell
    Citation: BMC Nephrology 2022 23:332
  42. There are major gaps in the implementation of guideline-concordant care for persons with chronic kidney disease (CKD). The CKD Cascade of Care (C3) initiative seeks to improve CKD care by improving detection and ...

    Authors: Julio A. Lamprea-Montealegre, Priya Joshi, Abigail S. Shapiro, Erin Madden, Krista Navarra, O. Alison Potok, L. Parker Gregg, Tanya Podchiyska, Amy Robinson, Mary K. Goldstein, Carmen A. Peralta, Simerjot K. Jassal, Sankar D. Navaneethan, Dena. E. Rifkin, Virginia Wang, Michael G. Shlipak…
    Citation: BMC Nephrology 2022 23:331

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