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  1. There has recently been considerable interest in better understanding how blood pressure should be managed after an episode of hospitalized AKI, but there are scant data regarding the associations between bloo...

    Authors: Ian McCoy, Sandeep Brar, Kathleen D. Liu, Alan S. Go, Raymond K. Hsu, Vernon M. Chinchilli, Steven G. Coca, Amit X. Garg, Jonathan Himmelfarb, T. Alp Ikizler, James Kaufman, Paul L. Kimmel, Julie B. Lewis, Chirag R. Parikh, Edward D. Siew, Lorraine B. Ware…

    Citation: BMC Nephrology 2021 22:270

    Content type: Research

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  2. Hepatitis C virus (HCV) and human immunodeficiency virus (HIV) cause a wide range of glomerular pathologies. In people with haemophilia, transfusion-associated infections with these viruses are common and defi...

    Authors: Nicholas Meyer, Wendy Cooper, Paul Kirwan, Roger Garsia, Scott Dunkley and David M. Gracey

    Citation: BMC Nephrology 2021 22:268

    Content type: Case report

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  3. Gemcitabine is a broadly prescribed chemotherapy, the use of which can be limited by renal adverse events, including thrombotic microangiopathy (TMA).

    Authors: Maximilien Grall, Florence Daviet, Noémie Jourde Chiche, François Provot, Claire Presne, Jean-Philippe Coindre, Claire Pouteil-Noble, Alexandre Karras, Dominique Guerrot, Arnaud François, Ygal Benhamou, Agnès Veyradier, Véronique Frémeaux-Bacchi, Paul Coppo and Steven Grangé

    Citation: BMC Nephrology 2021 22:267

    Content type: Research

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  4. To investigate if remote ischemic preconditioning (RIPC) can offer any renoprotective value by counteracting the deleterious effect of partial nephrectomy (PN) under warm ischemia on renal function.

    Authors: Tuna Till Mut, Ömer Acar, Ayse Armutlu, Said Incir, Annemarie Uhlig, Lale A. Ertuglu, Melis Özel, Ali Cihan Taskin, Dilek Ertoy Baydar, Mehmet Kanbay and Tarık Esen

    Citation: BMC Nephrology 2021 22:266

    Content type: Research article

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  5. Following an implementation plan based on dynamic dialogue between researchers and clinicians, this study implemented an evidence-based patient education program (tested in an RCT) into routine care at a clini...

    Authors: Kristin Hjorthaug Urstad, Astrid Klopstad Wahl, Torbjørn Moum, Eivind Engebretsen and Marit Helen Andersen

    Citation: BMC Nephrology 2021 22:265

    Content type: Research

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  6. The relationship between proton-pump inhibitor (PPI) use and chronic kidney disease (CKD) progression remains controversial. Specifically, there is a lack of data evaluating renal outcomes in established CKD p...

    Authors: Liza Cholin, Tarek Ashour, Ali Mehdi, Jonathan J. Taliercio, Remy Daou, Susana Arrigain, Jesse D. Schold, George Thomas, Joseph Nally, Nazih L. Nakhoul and Georges N. Nakhoul

    Citation: BMC Nephrology 2021 22:264

    Content type: Research

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  7. Polycystic Kidney Disease (PKD) is a hereditary disorder that has no cure and can result in end stage kidney failure. Searching for health information online and via social media is a common phenomenon in many...

    Authors: Tiffany Ma and Kelly Lambert

    Citation: BMC Nephrology 2021 22:263

    Content type: Research

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  8. Although anastomosing hemangiomas are very rare and benign vascular neoplasms, these tumors are more common among patients with end-stage kidney disease. Incidental finding of these tumors in the kidney or adr...

    Authors: Chang Seong Kim, Soo Jin Na Choi, Sung-Sun Kim, Sang Heon Suh, Eun Hui Bae, Seong Kwon Ma and Soo Wan Kim

    Citation: BMC Nephrology 2021 22:262

    Content type: Case report

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  9. Nephronophthisis (NPHP) is a chronic tubular interstitial disorder that exhibits an autosomal recessive genetic form and causes progressive renal failure in children. Patients with NPHP rarely show urinary abn...

    Authors: Maiko Akira, Hitoshi Suzuki, Arisa Ikeda, Masako Iwasaki, Daisuke Honda, Hisatsugu Takahara, Hisaki Rinno, Shigeki Tomita and Yusuke Suzuki

    Citation: BMC Nephrology 2021 22:261

    Content type: Case report

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  10. With an increase in the global popularity of coffee, caffeine is one of the most consumed ingredients of modern times. However, the consumption of massive amounts of caffeine can lead to severe hypokalemia.

    Authors: Min Jee Han, Su-Hyun Kim, Jung-ho Shin and Jin Ho Hwang

    Citation: BMC Nephrology 2021 22:260

    Content type: Case report

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  11. Health literacy refers to the ability of individuals to gain access to, use, and understand health information and services in order to maintain a good health. It is especially important in nephrology due to t...

    Authors: Annabel Boyer, Yannick Begin, Julie Dupont, Mathieu Rousseau-Gagnon, Nicolas Fernandez, Maryam Demian, David Simonyan, Mohsen Agharazii and Fabrice Mac-Way

    Citation: BMC Nephrology 2021 22:259

    Content type: Research

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  12. In spite of renal graft shortage and increasing waiting times for transplant candidates, simultaneous heart and kidney transplantation (HKTx) is an increasingly performed procedure established for patients wit...

    Authors: Oliver Beetz, Juliane Thies, Clara A. Weigle, Fabio Ius, Michael Winkler, Christoph Bara, Nicolas Richter, Jürgen Klempnauer, Gregor Warnecke, Axel Haverich, Murat Avsar and Gerrit Grannas

    Citation: BMC Nephrology 2021 22:258

    Content type: Research

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  13. Few studies have evaluated the clinical presentation, management, and outcomes of patients with end-stage renal disease (ESRD) presenting with acute aortic dissection (AAD) in real-world clinical practice. Thu...

    Authors: Jiahe Xie, Shan Zeng, Long Xie, Rongming Ding, Jing Hu, Hong Zeng, Weiling Lu, Yuhua Hu, Qingrui Li, Gaojun Zhong, Shiju Zhou, Ziyou Liu, Yulin Liao, Yiming Zhong and Dongming Xie

    Citation: BMC Nephrology 2021 22:257

    Content type: Research

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  14. CKD is common in heart failure (HF) and associated with morbidity and mortality, yet life-prolonging medications such as renin-angiotensin-aldosterone inhibitors (RAASi) are underused due to risk of hyperkalae...

    Authors: Daniel Murphy, Irina Chis Ster, Juan-Carlos Kaski, Lisa Anderson and Debasish Banerjee

    Citation: BMC Nephrology 2021 22:254

    Content type: Study protocol

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  15. Phospholipase A2 receptor 1 (PLA2R1) and thrombospondin type-1 domain-containing 7A (THSD7A) are the two major pathogenic antigens for membranous nephropathy (MN). It has been reported that THSD7A-associated M...

    Authors: Ayumi Matsumoto, Isao Matsui, Keiji Mano, Hitoshi Mizuno, Yusuke Katsuma, Seiichi Yasuda, Karin Shimada, Kazunori Inoue, Takashi Oki, Tadashi Hanai, Keiko Kojima, Tetsuya Kaneko and Yoshitaka Isaka

    Citation: BMC Nephrology 2021 22:253

    Content type: Case report

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  16. Thrombotic microangiopathy (TMA)-mediated acute kidney injury (AKI) following massive haemorrhage is a rare but severe complication of the post-partum period. It is associated with a poor renal prognosis and a...

    Authors: G. Guzzo, S. Kissling, G. Pantaleo, M. Pascual, S. Sadallah and D. Teta

    Citation: BMC Nephrology 2021 22:252

    Content type: Case report

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  17. The ongoing coronavirus pandemic has major impacts on both patients and healthcare systems worldwide, thus creating new realities. Patients on maintenance dialysis listed for renal transplantation are a vulner...

    Authors: Katharina Tuschen, Johanna Anders, Amin Elfanish, Verena Schildgen, Oliver Schildgen, Jan Ulrich Becker and Alexander Weidemann

    Citation: BMC Nephrology 2021 22:251

    Content type: Case report

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  18. Taurine depletion occurs in patients with end-stage chronic kidney disease (CKD). In contrast, in the absence of CKD, plasma taurine is reported to increase following dietary L-glutamine supplementation. This ...

    Authors: Nima Abbasian, Maryam Ghaderi-Najafabadi, Emma Watson, Jeremy Brown, Li Yu si, Debbie Bursnall, Izabella Pawluczyk, Anne-Marie Seymour and Alan Bevington

    Citation: BMC Nephrology 2021 22:250

    Content type: Research

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  19. Restless legs syndrome (RLS) is a common sleep-related movement disorder characterized by an urge to move the legs during inactivity, especially at evening-night. RLS is highly prevalent in patients with kidne...

    Authors: Davide Sparasci, Andrea Rossinelli, Raffaele Ferri, Pietro Cippà, Andrea Rinaldi and Mauro Manconi

    Citation: BMC Nephrology 2021 22:249

    Content type: Case report

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  20. Although uric acid (UA) is regarded as a risk factor for cardiovascular disease, whether UA is an independent risk factor contributing to coronary artery calcification in chronic kidney disease (CKD) is not we...

    Authors: Miyeun Han, Hyunsuk Kim, Hyo Jin Kim, Eunjeong Kang, Yong-Soo Kim, Kyu Hun Choi, Soo Wan Kim, Curie Ahn and Kook-Hwan Oh

    Citation: BMC Nephrology 2021 22:247

    Content type: Research

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  21. Poor physical function is strongly associated with mortality and poor clinical outcomes in adults with chronic kidney disease (CKD). Handgrip strength (HGS) is an important index for physical function in the g...

    Authors: Yang Cheng, Min Liu, Yu Liu, Haifeng Xu, Xiaotian Chen, Hui Zheng, Xiaojun Wu, Zhixiang Shen and Chong Shen

    Citation: BMC Nephrology 2021 22:246

    Content type: Research

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  22. Diabetic nephropathy (DN) is the major complication of diabetes mellitus, and leading cause of end-stage renal disease. The underlying molecular mechanism of DN is not yet completely clear. The aim of this stu...

    Authors: Alieh Gholaminejad, Mohammad Fathalipour and Amir Roointan

    Citation: BMC Nephrology 2021 22:245

    Content type: Research

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  23. Regional citrate anticoagulation (RCA) for the prevention of clotting of the extracorporeal blood circuit during continuous kidney replacement therapy (CKRT) has been employed in limited fashion because of the...

    Authors: Lenar Yessayan, Ryann Sohaney, Vidhit Puri, Benjamin Wagner, Amy Riddle, Sharon Dickinson, Lena Napolitano, Michael Heung, David Humes and Balazs Szamosfalvi

    Citation: BMC Nephrology 2021 22:244

    Content type: Research

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  24. Hyperphosphatemia is a common complication in patients on maintenance hemodialysis. Patients’ adherence to phosphorus control can be improved by consistent education. However, few studies have focused on the m...

    Authors: Jinmei Yin, Jun Yin, Rongli Lian, Peiqiu Li and Jing Zheng

    Citation: BMC Nephrology 2021 22:243

    Content type: Research

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  25. Minimal change disease is a common cause of nephrotic syndrome in adults. Higher relapse rate put patients at risk of steroids toxicity due to long-term exposure. Rituximab has been suggested to maintain long ...

    Authors: Diankun Liu, Zhanmei Zhou, Mengyi Wang, Sheng Nie, Jun Li, Bianxiang Hu, Wenjuan He, Guobao Wang and Jun Ai

    Citation: BMC Nephrology 2021 22:242

    Content type: Research

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  26. Kimuras disease (KD) is a rare chronic inflammatory disease and the etiology remains uncharacterized. The typical manifestations are painless lymph node or subcutaneous masses. There is currently no report of pr...

    Authors: Li Xiang, Hua Zhou, Hua Liu, Dachuan Zhang, Min Li, Min Yang and Yan Yang

    Citation: BMC Nephrology 2021 22:241

    Content type: Case report

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  27. Hypokalemia and acute kidney injury (AKI) occur in patients administered liposomal amphotericin B (L-AMB), a wide-spectrum anti-fungicidal drug. However, the association between potassium supplementation and t...

    Authors: Yuki Ota, Yoko Obata, Takahiro Takazono, Masato Tashiro, Tomotaro Wakamura, Akinori Takahashi, Yui Shiozawa, Taiga Miyazaki, Tomoya Nishino and Koichi Izumikawa

    Citation: BMC Nephrology 2021 22:240

    Content type: Research

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  28. Whether cigarette smoking is associated with the progression of immunoglobulin A nephropathy (IgAN) remains uncertain; therefore, we aimed to evaluate the effect of cigarette smoking on the prognosis of IgAN.

    Authors: Siqing Wang, Aiya Qin, Gaiqin Pei, Zheng Jiang, Lingqiu Dong, Jiaxing Tan, Li Tan, Yi Tang and Wei Qin

    Citation: BMC Nephrology 2021 22:239

    Content type: Research

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  29. Acute kidney injury (AKI) is a frequently encountered clinical condition in critically ill patients and is associated with increased morbidity and mortality. In our resource-limited setting (RLS), the most com...

    Authors: Davis Kimweri, Julian Ategeka, Faustine Ceasor, Winnie Muyindike, Edwin Nuwagira and Rose Muhindo

    Citation: BMC Nephrology 2021 22:238

    Content type: Research

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  30. Diffusion-weighted (DW) and blood oxygen level-dependent (BOLD) magnetic resonance imaging are classical sequences of functional MR, but the exploration in non-transplanted kidney disease is limited. Objects: ...

    Authors: Tao Su, Xuedong Yang, Rui Wang, Li Yang and Xiaoying Wang

    Citation: BMC Nephrology 2021 22:237

    Content type: Research article

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  31. Activation of the transforming growth factor beta (TGF-β) pathway is a significant contributor to the pathogenesis of diabetic nephropathy. Carnosine is a dipeptide that can inhibit TGF-β synthesis. We tested ...

    Authors: Narongrit Siriwattanasit, Bancha Satirapoj and Ouppatham Supasyndh

    Citation: BMC Nephrology 2021 22:236

    Content type: Research article

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  32. Contrast-associated acute kidney injury (CA-AKI) is a common complication with poor prognosis after coronary angiography (CAG). With the prevention methods widely being implemented, the temporal trends of inci...

    Authors: Jin Liu, Qiang Li, Disheng Lai, Guoqin Chen, Bo Wang, Liwei Liu, Haozhang Huang, Zhubin Lun, Ming Ying, Guanzhong Chen, Zhidong Huang, Danyuan Xu, Liangguang Meng, Xiaoming Yan, Weiyan Qiu, Ning Tan…

    Citation: BMC Nephrology 2021 22:235

    Content type: Research

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  33. Most studies of chronic kidney disease (CKD) in Sub-Saharan Africa (SSA) have been conducted in urban settings. They relied on GFR estimated from serum creatinine alone and on the inexpensive, convenient urina...

    Authors: Mannix Imani Masimango, Michel P. Hermans, Espoir Bwenge Malembaka, Pierre Wallemacq, Ernest Kiswaya Sumaili, Catherine Fillée, William D’Hoore, Cheryl A. Winkler, Sophie Limou and Michel Jadoul

    Citation: BMC Nephrology 2021 22:234

    Content type: Research

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  34. Patient-reported outcome (PRO) instruments should capture the experiences of disease and treatment that patients consider most important in order to inform patient-centred care and product development. The aim...

    Authors: Jennifer E. Flythe, Niklas Karlsson, Anna Sundgren, Paul Cordero, Amanda Grandinetti, Henry Cremisi and Anna Rydén

    Citation: BMC Nephrology 2021 22:233

    Content type: Research

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  35. After dialysis initiation, older adults may experience orthostatic or post-dialysis hypotension. Some orthostasis-causing antihypertensives (i.e., central alpha agonists and alpha blockers), are considered pot...

    Authors: Rasheeda K. Hall, Sarah Morton, Jonathan Wilson, Patti L. Ephraim, L. Ebony Boulware, Wendy L. St. Peter, Cathleen Colón-Emeric, Jane Pendergast and Julia J. Scialla

    Citation: BMC Nephrology 2021 22:232

    Content type: Research

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  36. Common subtypes seen in Chinese patients with membranous nephropathy (MN) include idiopathic membranous nephropathy (IMN) and hepatitis B virus-related membranous nephropathy (HBV-MN). However, the morphologic...

    Authors: Tianqi Tu, Xueling Wei, Yue Yang, Nianrong Zhang, Wei Li, Xiaowen Tu and Wenge Li

    Citation: BMC Nephrology 2021 22:231

    Content type: Research article

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  37. IgA nephropathy (IgAN) is the most common primary glomerulonephritis worldwide. Although most IgAN cases are sporadic, few show a familial aggregation. However, the prevalence and prognosis of IgAN individuals...

    Authors: Yoshinori Sato, Hiroyasu Tsukaguchi, Koichiro Higasa, Naoto Kawata, Kiyoko Inui, Tran Nguyen Truc Linh, Tran Thuy Huong Quynh, Inoue Yoshihiko, Fumihiko Koiwa and Ashio Yoshimura

    Citation: BMC Nephrology 2021 22:230

    Content type: Research

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  38. Worldwide, hypertensive disorders in pregnancy (HDPs) complicate between 5 and 10% of pregnancies. Sub-Saharan Africa (SSA) is disproportionately affected by a high burden of HDPs and chronic kidney disease (C...

    Authors: Salisu M. Ishaku, Timothy Olusegun Olanrewaju, Joyce L. Browne, Kerstin Klipstein-Grobusch, Gbenga A. Kayode, Arie Franx, Diederick E. Grobbee and Charlotte E. Warren

    Citation: BMC Nephrology 2021 22:229

    Content type: Research

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  39. Silver nanoparticles (AgNPs) can accumulate in various organs after oral exposure. The main objective of the current study is to evaluate the renal toxicity induced by AgNPs after repeated oral exposure and to...

    Authors: Hamed Nosrati, Manijeh Hamzepoor, Maryam Sohrabi, Massoud Saidijam, Mohammad Javad Assari, Nooshin Shabab, Zahra Gholami Mahmoudian and Zohreh Alizadeh

    Citation: BMC Nephrology 2021 22:228

    Content type: Research

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  40. End-stage Kidney Disease patients have a high mortality and hospitalization risk. The association of these outcomes with physical activity is described in the general population and in other chronic diseases. ...

    Authors: Pedro Martins, Elisa A. Marques, Diogo V. Leal, Aníbal Ferreira, Kenneth R Wilund and João L. Viana

    Citation: BMC Nephrology 2021 22:227

    Content type: Research

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  41. Early diagnosis and treatment of Polyomavirus BK Nephropathy (PVBKN) is a challenging issue in the management of patients with kidney transplantation. Currently, histopathologic diagnosis is the gold standard ...

    Authors: Fatemeh Nili, Maliheh Mohammadhoseini, Seyed Mohammadreza Khatami, Golnar Seirafi and Majidreza Haghzare

    Citation: BMC Nephrology 2021 22:226

    Content type: Research

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  42. Chronic kidney disease is highly prevalent across the globe with more than 2 million people worldwide requiring renal replacement therapy. Interdialytic weight gain is the change in body weight between two ses...

    Authors: Soraiya Manji, Jasmit Shah, Ahmed Twahir and Ahmed Sokwala

    Citation: BMC Nephrology 2021 22:225

    Content type: Research

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  43. Coronavirus-19 (COVID-19) has been declared a global pandemic by the World Health Organisation. Severe disease typically presents with respiratory failure but Acute Kidney Injury (AKI) and a hypercoagulable st...

    Authors: Kathrine Parker, Patrick Hamilton, Prasanna Hanumapura, Laveena Castelino, Michelle Murphy, Rachael Challiner, Jecko Thachil and Leonard Ebah

    Citation: BMC Nephrology 2021 22:224

    Content type: Research

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  44. Diabetic kidney disease (DKD) is a major long-term complication of diabetes mellitus (DM). Given the paucity of data on DKD in Jordan, we aimed to evaluate the prevalence, characteristics and correlates of DKD...

    Authors: Randa I. Farah, Mohammed Q. Al-Sabbagh, Munther S. Momani, Asma Albtoosh, Majd Arabiat, Ahmad M. Abdulraheem, Husam Aljabiri and Mohammad Abufaraj

    Citation: BMC Nephrology 2021 22:223

    Content type: Research

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  45. Von Willebrand Factor (VWF) multimers are cleaved into smaller and less coagulant forms by the metalloprotease ADAMTS13. The aim of this study was to investigate the association between VWF and ADAMTS13 and mo...

    Authors: Gurbey Ocak, Mark Roest, Marianne C. Verhaar, Maarten B. Rookmaaker, Peter J. Blankestijn, Willem Jan W. Bos, Rob Fijnheer, Nathalie C. Péquériaux and Friedo W. Dekker

    Citation: BMC Nephrology 2021 22:222

    Content type: Research article

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  46. Increasing the blood flow rate (BFR) is a useful method for increasing Kt/V and the clearance for low molecular solutes. Hemodialysis patients are often anemic due to hypoerythropoiesis and their chronic infla...

    Authors: Masateru Yamamoto, Tomio Matsumoto, Hiromitsu Ohmori, Masahiko Takemoto, Masanobu Ikeda, Ryo Sumimoto, Tsuyoshi Kobayashi, Akihiko Kato and Hideki Ohdan

    Citation: BMC Nephrology 2021 22:221

    Content type: Research

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