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Table 3 Haemodynamic consequences of using citric instead of acetic acid in dialysis fluids II.

From: Citrate- vs. acetate-based dialysate in bicarbonate haemodialysis: consequences on haemodynamics, coagulation, acid-base status, and electrolytes

  

Acetate (A)

Citrate (C)

Citrate (C+)

P(Avs.C)

P(Avs.C+)

Systolic BP (mmHg)

max.decrease

19.2 ± 9.61

25.6 ± 10.98

23.4 ± 13.43

< 0.01

ns

 

max.increase

13.96 ± 8.28

9.07 ± 7.84

11.01 ± 8.32

< 0.05

ns

Diastolic BP (mmHg)

max.decrease

10.60 ± 4.06

12.18 ± 5.13

10.68 ± 5.99

ns

ns

 

max.increase

7.42 ± 5.56

7.33 ± 5.54

7.95 ± 5.03

ns

ns

Blood volume # (%)

max.decrease

6.05 ± 4.21

4.81 ± 3.51

6.47 ± 3.88

ns

ns

 

max increase

0.99 ± 0.95

1.21 ± 1.26

0.44 ± 0.70

ns

< 0.05

Heart rate # (beat/min)

max.decrease

8.04 ± 5.99

7.79 ± 5.76

7.81 ± 6.92

ns

ns

 

max increase

4.03 ± 3.21

3.27 ± 2.95

4.03 ± 4.28

ns

ns

Stroke volume (ml)

max.decrease

17.20 ± 9.78

19.62 ± 10.41

14.90 ± 16.65

ns

ns

 

max.increase

28.14 ± 15.22

28.26 ± 32.24

23.04 ± 23.97

ns

ns

Peripheral resistence

max.decrease

973.60 ± 571.25

485.30 ± 267.25

410.37 ± 330.91

< 0.001

< 0.001

(dyne.sec.cm-5)

max.increase

904.73 ± 376.18

791.69 ± 464.17

741.30 ± 528.75

ns

ns

  1. Blood volume, blood pressure (BP), heart rate, stroke volume and peripheral resistance fluctuations during dialysis using acetate dialysate (A) vs. citrate dialysate with (C+) or without (C) calcium supplementation.