Table 1 Demographic and clinical characteristics of type 2 diabetics in the Health Professionals Follow-Up Study (HPFS) and Nurses' Health Study (NHS)
| Â | HPFS in 1994 (n = 733) | NHS in 1990 (n = 833) |
|---|---|---|
Age (years) | 65.5 ± 7.9 (47–80) | 59.5 ± 6.3 (43–70) |
African-American | 11 (1.5) | 12 (1.4) |
Hypertension | 399 (45.6) | 568 (68.2) |
Weight (kg) | 88.1 ± 16.2 (56.8–210.9) | 80.4 ± 18.1 (38.6–154.5) |
Body Mass Index (BMI) (kg/m 2 ) | 27.8 ± 4.4 (18.3–56.5) | 29.9 ± 6.2 (15.1–54.9) |
BMI categories (kg/m 2 ) | Â | Â |
   <22 | 33 (4.5) | 78 (9.3) |
   22–24.9 | 160 (21.8) | 102 (12.2) |
   25–27.9 | 229 (31.2) | 155 (18.6) |
   28–29.9 | 131 (17.9) | 110 (13.2) |
   ≥ 30 | 180 (24.6) | 384 (46.1) |
Activity (METs/week) | 29.6 ± 33.0 (0–228.8) | 15.3 ± 20.3 (0.2–190.7) |
Cigarette smoking | Â | Â |
   Current | 43 (5.8) | 113 (13.6) |
   Past | 392 (53.5) | 341 (40.9) |
   Never | 261 (35.7) | 377 (45.3) |
   Missing | 37 (5.1) | 2 (0.2) |
Time since diagnosis of Type 2 diabetes (years) | 11.2 ± 9.1 (0.1–41.1) | 10.3 ± 8.0 (0.1–41.1) |
Measured HbA1c (%) | 7.5 ± 1.6 (4.8–15.6) | 7.2 ± 1.8 (4.4–15.4) |
Baseline coronary heart disease (MI, revascularization, or angina) | 194 (26.5) | 216 (25.9) |
ACE-inhibitor medication use | 60 (8.2) | 81 (9.7) |
Statin medication use | 48 (6.6) | Not available |
Measured plasma creatinine (mg/dl) | 1.1 ± 0.2 (0.6–2.9) | 0.8 ± 0.2 (0.5–2.4) |
Creatinine clearance (ml/min) | 91 ± 30 (22–241) | 100 ± 33 (17–244) |
eGFR (ml/min/1.73 m 2 ) | 79 ± 18 (23–142) | 83 ± 19 (22–139) |