Interventions for renal vasculitis in adults. A systematic review

BMC Nephrology

Table 9 Summary of quality measures of included studies

Study ID	Randomisation method	Allocation concealment	Blinding: Participants	Blinding: Investigators	Blinding: Outcome assessors	Blinding: Data assessors	ITT	% Follow-up
Adu 1997	Computer generated random numbers. Stratified for renal function	A	No	No	No	No	Yes	100
Cole 1992	computer-generated random numbers after informed consent Stratified by urine volume (< 400 ml/24 h), need for dialysis and > 50% glomeruli sclerosed	B	No	No	Yes	No	No	97
De Groot 2009a	computer generated, performed centrally by permuted blocks of 4, stratified by country and disease. assigned randomly 1:1 to treatments.	A	No	No	No	Yes	Yes	83
Furuta 1998	NS	B	No	No	NS	NS	Yes	100
Jayne 2007	NS	B	No	No	NS	NS	Yes	100
Glockner 1988	By telephone with statistician	B	No	No	NS	NS	No	84
Guillevin 1997	NS	B	No	No	NS	NS	No	93
Haubitz 1998	Stratified at diagnosis	B	No	No	NS	NS	No	84
Jayne 2007	Centrally, block design. Stratified by diagnosis	A	NS	NS	NS	Yes	Yes	100
Mauri 1985	NS	B	No	No	NS	NS	Yes	100
Pusey 1991	Stratified for severity according to renal function by random numbers	B	No	No	NS	NS	No	92
Rifle 1980	NS	B	No	No	NS	NS	No	82
Stegeman 1996	Stratified by group and then randomized	B	Yes	Yes	Yes	NS	No	99
Stegmayr 1999	NS	B	No	No	NS	NS	No	83
Hu 2008	Not stated	B	No	No	No	NS	Yes	89
Jayne 2000	Central	A	Yes	Yes	Yes	NS	Yes	100
Metzler 2007	Central	A	No	No	No	No	Yes	96
WGET 2000	Stratified by disease severity and by centre	A	Yes	Yes	Yes	NS	Yes	97
Pagnoux 2008	Permuted blocks of six	A	No	No	No	NS	Yes	100
Hiemstra 2009	NS	NS	No	No	NS	NS	Yes	NS
RAVE	NS	NS	Yes	Yes	NS	NS	NS	NS
RITUXVAS	Central randomisation	Yes	No	No	NS	NS	Yes	100

ISSN: 1471-2369