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Table 5 Randomized controlled trials comparing the hemodynamic tolerability of CRRT and IHD

From: The hemodynamic tolerability and feasibility of sustained low efficiency dialysis in the management of critically ill patients with acute kidney injury

 

CRRT (n)

IHD

(n)

Definition of Hemodynamic Tolerability

Outcome

Misset et al a[4]

27

27

Amplitude of MAP change (lowest recorded every hour to highest recorded), and episodes of MAP reduction by > 10 mmHg

No significant difference (p = 0.72 and 0.73, respectively)

Augustine et al [6]

40

40

Difference between mean MAP in 12 hours prior to RRT and during RRT

Significant drop in MAP during IHD (p = 0.04)

Uehlinger et al [7]

70

55

Number of hypotensive events (MAP < 65) during RRT

No significant difference

(p = 0.36)

Vinsonneau et al [8]

175

184

Number of hypotensive events (SBP < 80, or drop of greater than 50 mmHg) during RRT

No significant difference

(p = 0.47)

  1. aA cross-over study with a 24-hour wash-out period
  2. MAP, mean arterial pressure; SBP, systolic blood pressure