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Table 2 Association of UMOD Genotype at rs12917707 and UMOD Levels

From: Uromodulin concentrations are not associated with incident CKD among persons with coronary artery disease

Characteristics

G/G (n = 48)

G/T (n = 48)

T/T (n = 24)

P value

Overall

UMOD (median IQR)

142 (87-249)

128 (64-207)

83 (33-159)

0.11

Linear Regression (log transformed) (β Coefficient, p-value)

Unadjusted

Reference

-0.2

-0.7

-

  

p = 0.36

p = 0.002

 

Adjusted *

Reference

-0.2

-0.8

-

  

p = 0.38

p = 0.001

 

Restricted to Whites

UMOD (median IQR)

152 (105-268)

129 (67-207)

97 (33-170)

0.23

Linear Regression (log transformed) (β Coefficient, p-value)

Unadjusted

Reference

-0.4

-0.8

-

  

p = 0.09

p = 0.001

 

Adjusted *

Reference

-0.4

-0.9

-

  

p = 0.10

p < 0.001

 
  1. P values are obtained using Kruskal-Wallis rank test for mean comparison and non-parametric median test for median comparison.
  2. *Adjusted for age, sex, race, BMI, diabetes, and hypertension
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BMC Nephrology

ISSN: 1471-2369

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