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Table 3 Evaluation at the amino acid level by SKDM

From: The association of HLA-DQB1, -DQA1 and -DPB1 alleles with anti- glomerular basement membrane (GBM) disease in Chinese patients

HLA-DPB1 Residues

Alls

Pos

AA

Assoc

p

pc

OR

0401

35

F

-

0.031

1

0.04

0401

69

K

-

0.0067

0.31

0.28

HLA-DPB1 Pocket Residues

pc

Pocket 4 (Pos:13,69,76,68,72,24)

0.17

Pocket 7 (Pos: 26,59,69,45,65)

0.17

Pocket 9 (Pos: 9,58,55,35,36)

0.83

  1. [Abbreviations] Alls, alleles; Pos, position; AA, amino acid; Assoc, association; pc, P corrected; OR, odds ratio; F, phenylalanine; K, lysine.