Table 6 PTH and calcium-phosphorus metabolism.

Phosphorus (mg/dL; mean ± SD [range])

3.7 ± 0.7 [1.7-6.7]

3.5 ± 0.6 [1.7-6.2]

3.8 ± 0.7 [1.7-6.7]

0.001

Serum phosphous within the K-DOQI target (2.8-4.6 mg/dL) (%)

85.1

86.8

83.5

0.12

Corrected calcium (mg/dL; mean ± SD [range])

9.3 ± 0.5 [7-11.8]

9.3 ± 0.5 [7.9-11.6]

9.3 ± 0.5 [7-11.8]

0.64

Serum calcium within the K-DOQI target (8.4-9.5 md/dL) (%)

57.6

57.5

57.6

0.99

Calcium-Phosphorus product (mg/dL, mean[SD] [Range]

35 ± 6 [14-65]

33 ± 6 [17-59]

36 ± 7 [14-65]

0.002

Percentage of patients with calcium levels below normal (< 8.4 mg/dl)

3.3

2.1

4.0

NS

Percentage of patients with phosphorus levels above normal

9.4

2.6

13.6

0.001

Calcium-Phosphorus product within the K-DOQI target (< 55 mg²/dL²) (%)

98.6

99.5

98.1

0.047

i-PTH (pg/mL; mean ± SD [range])

145 ± 116 [0-1166]

121 ± 99 [0-468]

166 ± 125 [9-1166]

0.001

Serum i-PTH within the K-DOQI target (%) [35-70 pg/mL (stage 3) or 70-110 pg/mL (stage 4)]

24.4

28.7

20.7

0.003

Meeting all four parameters according to K-DOQI guidelines (%)

10.5

12.2

9.0

0.10

Treatment with vitamin D (ergocalciferol/calcitriol) (%)

15.0

10.6

18.9

0.001

Treatment with phosphate binders (%)

19.7

11.9

26.7

0.001