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Table 2 The association between indicators of kidney damage with ocular fundus pathology.

From: Ocular fundus pathology and chronic kidney disease in a Chinese population

 

eGFR ((mL/min/1.73m2)

Proteinuria

CKD

 

≥90

60-89

<60

  

Any ocular fundus pathology

     

   Crude OR (95% CI)

Reference

5.18 (4.64-5.77)

9.12 (7.30-11.38)

1.53 (1.33-1.77)

1.96 (1.73-2.23)

   Age-, sex- adjusted OR (95% CI)

Reference

1.03 (0.89-1.19)

1.26 (0.96-1.65)

1.45 (1.22-1.73)

1.36 (1.17-1.59)

   Fully adjusted OR (95% CI)*

Reference

0.97 (0.84-1.13)

1.07 (0.79-1.45)

1.29 (1.07-1.55)

1.18 (0.99-1.41)

Retinopathy

     

   Crude OR (95% CI)

Reference

5.87 (5.20-6.62)

7.76 (7.77-12.45)

1.63 (1.40-1.90)

2.05 (1.79-2.34)

   Age-, sex- adjusted OR (95% CI)

Reference

0.96 (0.82-1.12)

1.05 (0.78-1.40)

1.55 (1.28-1.87)

1.38 (1.17-1.64)

   Fully adjusted OR (95% CI)*

Reference

0.91 (0.77-1.07)

0.92 (0.66-1.27)

1.37 (1.12-1.67)

1.19 (0.98-1.44)

  1. * Covariates included in the fully adjusted models were: age (continuous), sex, BMI (<18.5, 18.5-24.9, 25.0-27.0, ≥27.0; kg/m2), hypertension (yes/no), diabetes (yes/no), history of CVD (yes/no)), plasma uric acid (continuous).
  2. The number of participants with any ocular fundus pathology and retinopathy was 2037 and 1670, respectively.
  3. eGFR: estimated glomerular filtration rate; CKD, chronic kidney disease; OR, odds ratio; CI, confidence interval.