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Table 4 Correlations between urinary complement levels and fibrosis in IgAN patients

From: Excretion of complement proteins and its activation marker C5b-9 in IgA nephropathy in relation to renal function

 

Interstitial fibrosis

 

Percentage of global glomerular sclerosis

as a fraction of all glomeruli

 

r

p

 

r

p

MAC

0.476

p < 0.01

 

0.361

p < 0.01

fH

0.383

p < 0.05

 

0.411

p < 0.01

P

0.310

p = 0.054

 

0.215

p = 0.099

CR1

-0.179

p = 0.279

 

-0.158

p = 0.229

U-protein

0.421

p < 0.01

 

0.339

p < 0.01

  1. Abbreviations: MAC, membrane attack complex; fH, factor H; P, properdin; CR1, complement receptor 1; U-protein, Urinary protein