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Table 2 Results in VDRA + −group

From: Effect of vitamin-D analogue on albuminuria in patients with non-dialysed chronic kidney disease stage 4–5: a retrospective single center study

 

Before

After

P

Kidney Function

eGFR (ml/min/1,73 m2)

14.7 ± 4.3

13.0 ± 4.6

<0.001

U-Albumin (g/d)

1.81 ± 1.77

1.56 ± 1.57

<0.05

Mineral-Bone

S-calcium (mmol/l)

1.15 ± 0.08

1.14 ± 0.07

ns

S-phosphate (mmol/l)

1.52 ± 0.35

1.56 ± 0.39

ns

S-PTH (pmol/l)

29.5 ± 14.9

26.0 ± 11.3

ns

Blood Pressure

Systolic (mmHg)

151 ± 20

146 ± 19

<0.05

Diastolic (mmHg)

85 ± 11

83 ± 11

ns

Antihypertensives: (n)

Angiotensin inhibitors*

21

22

 

Angiotensin receptor blockers*

24

25

 

Calcium antagonists

37

44

 

Beta- blockers

28

35

 

Others

5

9

 
  1. *5 dual in both groups.
  2. Effects of starting treatment with alfacalcidol in 59 patients with secondary hyperparathyroidism and CKD 4–5. Mean ± SD.