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Figure 2 | BMC Nephrology

Figure 2

From: Increasing extracellular matrix collagen level and MMP activity induces cyst development in polycystic kidney disease

Figure 2

Effect of collagen I concentrations on the formation of cyst or tubule structures in 3D collagen I gel cultures. A . percentage of cyst and tubule structures formed in 3D collagen gels with a collagen I concentration of 0.8, 1.0, 1.2, 1.5, 1.8 and 2.0 mg/ml, respectively. B. a representative tubule and cyst section stained with DAPI to show the single cell layer of tubule and cyst structures (Scale bar, 50 μm). C. a representative picture of cyst and tubule structures formed in 1.0, 1.2, and 1.8 mg/ml collagen I gels (Scale bars, 200 μm).

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BMC Nephrology

ISSN: 1471-2369

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