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Figure 6 | BMC Nephrology

Figure 6

From: Increasing extracellular matrix collagen level and MMP activity induces cyst development in polycystic kidney disease

Figure 6

Doxycycline decreases the number of PCNA positive tubule/cyst cells in PKD kidneys of PCK rats. A . The number of PCNA-positive cells per 20X power field in vehicle- and doxycycline-treated PKD kidneys. *p < 0.005 versus PKD vehicle. B and C. The representative pictures of PCNA nuclear staining (brown color) in vehicle- (B) and doxycycline-treated (C) PKD kidneys (Scale bars: 50 μm).

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