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Table 2 Hazard ratios of all-cause and cardiovascular mortality based on univariate Cox regression models

From: Cardiovascular determinants of prognosis in normotensive hemodialysis patients

Variable

All-cause mortality

Cardiovascular mortality

Hazard Ratio (95% CI)

P value

Hazard Ratio (95% CI)

P value

Age (year)

1.08 (1.05-1.11)

<0.001

1.09 (1.04-1.14)

<0.001

Sex (men = 1, female = 0)

1.15 (0.64-2.03)

0.6

0.91 (0.35-2.38)

0.9

BMI (kg/m2)

1.02 (0.94-1.11)

0.7

1.04 (0.91-1.20)

0.5

Diabetes (yes =1, no = 0)

4.47 (2.28-8.76)

<0.001

7.80 (2.91-20.92)

<0.001

History of cardiovascular disease (yes = 1, no = 0)

2.85 (1.47-5.45)

0.002

3.10 (1.08-8.93)

0.04

Dialysis duration (days)

1.0 (0.99-1.00)

0.4

1.0 (1.00-1.00)

0.4

Systolic BP (mmHg)

0.99 (0.98-1.01)

0.9

1.01 (0.98-1.04)

0.4

Diastolic BP (mmHg)

0.98 (0.96-1.004)

0.9

1.02 (0.97-1.06)

0.7

Pulse BP (mmHg)

1.00 (0.97-1.03)

0.9

1.03 (0.99-1.08)

0.5

Systolic BPavg (mmHg)

0.99 (0.98-1.006)

0.2

1.01 (0.99-1.04)

0.3

Diastolic BPavg (mmHg)

0.97 (0.94-0.99)

0.03

1.00 (0.93-1.07)

0.9

Pulse BPavg (mmHg)

1.00 (0.98-1.02)

0.7

1.03 (0.99-1.06)

0.2

Hematocrit (%)

0.91 (0.84-0.99)

0.04

0.91 (0.78-1.04)

0.2

Kt/V

0.43 (0.16-1.15)

0.09

0.52 (0.11-2.49)

0.4

LVMI (g/height2.7)

1.02 (1.005-1.04)

0.01

1.04 (1.02-1.06)

<0.001

LV EF (%)

0.97 (0.947-0.998)

0.03

0.94 (0.91-0.97)

<0.001

Aorta dimension (mm)

1.69 (0.73-3.92)

0.2

1.36 (0.34-5.45)

0.7

Carotid IMT(μm)

1.002 (1.001-1.004)

0.02

1.0053 (1.001-1.006)

0.003

Carotid augmentation index (%)

1.00 (0.98-1.02)

0.9

1.01 (0.98-1.04)

0.4

Carotid Einc (kPa *103)

2.45 (0.70-8.56)

0.2

2.61 (0.35-19.34)

0.4

Aortic PWV (m/s)

1.13 (1.06-1.20)

<0.001

1.19 (1.09-1.29)

<0.001

  1. BMI = body mass index; BP = blood pressure; BPavg = pre-dialysis blood pressure averaged from 25 consecutive hemodialysis sessions; Einc = incremental elastic modulus; IMT = intima-media thickness; LV EF = left ventricular ejection fraction; LVMI = left ventricular mass index; PWV = pulse wave velocity.