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Table 1 Clinical and biological data at admission in the intensive care unit

From: Diagnostic value of urine sCD163 levels for sepsis and relevant acute kidney injury: a prospective study

Characteristics

  SIRS

Sepsis

 n = 20

Total n = 40

Survivors n = 20

Non-survivors n = 20

Age (years)

55.4 ± 21.4

56.2 ± 19.8

52.7 ± 21.5

59.8 ± 17.8

Gender (n, %)

    

Male

7 (35)

28 (70)

16 (80)

8 (40)

Female

13 (65)

12 (30)*

4 (20)

12 (60)

temperature (°C)

37.31 ± 0.6

37.70 ± 1.1

37.97 ± 0.9

37.43 ± 1.1

WBC counts (×109/L)

11.7 (9.3-13.0)

10.5 (7.7-17.0)

10.1 (7.7-12.6)

12.6 (7.4-21.9)

serum CRP (mg/dl)

3.4 (1.7-6.0)

11.6 (4.3-17.1)*

8.4 (3.1-15.5)

13.1 (6.1-18.2)

serum PCT (ng/ml)

0.3 (0.2-1.4)

1.9 (0.4-7.4)

1.9 (0.2-7.9)

2.0 (0.6-7.9)

serum sCD163 (ng/ml)

0.3 (0.2-0.4)

2.9 (1.6-11.3)*

1.7 (1.1-4.5)

10.2 (2.7-18.2)#

Renal characteristics

    

Urinary output (ml/Kg/hr)

-

1.5 (1.1-1.9)

1.5 (1.0-1.9)

1.5 (1.1-2.1)

CCr(ml/min)

-

90.1 (38.5-120.3)

94.3 (65.7-141.5)

53.1 (31.2-107.0)

SCr(μmmol/L)

-

68.0 (55.8-130.7)

63.1 (53.6-96.6)

79.5 (62.1-110.1)

BUN(mmol/L)

-

9.2 (6.5-15.6)

7.7 (5.9-10.3)

11.5 (8.9-29.9)#

APACHEII score

11.8 ± 6.7

16.6 ± 7.3*

12.3 ± 6.4

20.9 ± 5.5#

SOFA score

-

7.9 ± 4.0

6.1 ± 2.9

9.6 ± 4.2#

MV (n, %)

13 (65)

31 (77.5)

14 (70)

17 (85)

CRRT (n, %)

1 (5)

12 (30)*

4 (20)

8 (40)

Etiological factors (n, %)

    

Pulmonary infection

-

35 (87.5)

18 (90)

17 (85)

Abdominal infection

-

9 (22.5)

6 (30)

3 (15)

Urinary tract infection

-

11 (27.5)

8 (40)

3 (15)

Trauma/postoperative infection

-

16 (40)

10 (50)

6 (30)

Bacteremia

-

13 (32.5)

8 (40)

5 (25)

Catheter-related infections

-

8 (20)

5 (25)

3 (15)

Others

-

1 (2.5)

1 (5)

0 (0)

Pathogens (n, %)

    

Gram-positive bacteria

-

 

11 (55)

8 (40)

Gram-negative bacteria

-

 

18 (90)

15 (75)

Fungi

-

 

11 (55)

11 (55)

underlying diseases (n, %)

    

Hypertension

6 (30)

12 (30)

6 (30)

6 (30)

Diabetes

2 (10)

7 (17.5)

3 (15)

4 (20)

COPD

0 (0)

3 (7.5)

3 (15)

0 (0)

Coronary heart disease

3 (15)

4 (10)

2 (10)

2 (10)

Immunosuppressed

0 (0)

7 17.5)

2 (10)

5 (25)

Nervous system disease

0 (0)

3 (7.5)

2 (10)

1 (5)

CKD

1 (5)

7 (17.5)

3 (15)

2 (10)

  1. Quantitative data of normal distribution are presented as mean ± SD. Quantitative data of non-normal distribution are presented as median (25th and 75th percentiles). Qualitative data are presented as n (%).
  2. APACHE score, Acute Physiologic Assessment and Chronic Health Evaluation II scores; SOFA score, Sequential Organ Failure Assessment scores; MV, mechanical ventilation; CRRT, continuous renal replacement therapy; COPD, chronic obstructive pulmonary disease; CKD, chronic kidney disease.