Characteristics |   SIRS | Sepsis | ||
---|---|---|---|---|
 n = 20 | Total n = 40 | Survivors n = 20 | Non-survivors n = 20 | |
Age (years) | 55.4 ± 21.4 | 56.2 ± 19.8 | 52.7 ± 21.5 | 59.8 ± 17.8 |
Gender (n, %) | ||||
Male | 7 (35) | 28 (70) | 16 (80) | 8 (40) |
Female | 13 (65) | 12 (30)* | 4 (20) | 12 (60) |
temperature (°C) | 37.31 ± 0.6 | 37.70 ± 1.1 | 37.97 ± 0.9 | 37.43 ± 1.1 |
WBC counts (×10∧9/L) | 11.7 (9.3-13.0) | 10.5 (7.7-17.0) | 10.1 (7.7-12.6) | 12.6 (7.4-21.9) |
serum CRP (mg/dl) | 3.4 (1.7-6.0) | 11.6 (4.3-17.1)* | 8.4 (3.1-15.5) | 13.1 (6.1-18.2) |
serum PCT (ng/ml) | 0.3 (0.2-1.4) | 1.9 (0.4-7.4) | 1.9 (0.2-7.9) | 2.0 (0.6-7.9) |
serum sCD163 (ng/ml) | 0.3 (0.2-0.4) | 2.9 (1.6-11.3)* | 1.7 (1.1-4.5) | 10.2 (2.7-18.2)# |
Renal characteristics | ||||
Urinary output (ml/Kg/hr) | - | 1.5 (1.1-1.9) | 1.5 (1.0-1.9) | 1.5 (1.1-2.1) |
CCr(ml/min) | - | 90.1 (38.5-120.3) | 94.3 (65.7-141.5) | 53.1 (31.2-107.0) |
SCr(μmmol/L) | - | 68.0 (55.8-130.7) | 63.1 (53.6-96.6) | 79.5 (62.1-110.1) |
BUN(mmol/L) | - | 9.2 (6.5-15.6) | 7.7 (5.9-10.3) | 11.5 (8.9-29.9)# |
APACHEII score | 11.8 ± 6.7 | 16.6 ± 7.3* | 12.3 ± 6.4 | 20.9 ± 5.5# |
SOFA score | - | 7.9 ± 4.0 | 6.1 ± 2.9 | 9.6 ± 4.2# |
MV (n, %) | 13 (65) | 31 (77.5) | 14 (70) | 17 (85) |
CRRT (n, %) | 1 (5) | 12 (30)* | 4 (20) | 8 (40) |
Etiological factors (n, %) | ||||
Pulmonary infection | - | 35 (87.5) | 18 (90) | 17 (85) |
Abdominal infection | - | 9 (22.5) | 6 (30) | 3 (15) |
Urinary tract infection | - | 11 (27.5) | 8 (40) | 3 (15) |
Trauma/postoperative infection | - | 16 (40) | 10 (50) | 6 (30) |
Bacteremia | - | 13 (32.5) | 8 (40) | 5 (25) |
Catheter-related infections | - | 8 (20) | 5 (25) | 3 (15) |
Others | - | 1 (2.5) | 1 (5) | 0 (0) |
Pathogens (n, %) | ||||
Gram-positive bacteria | - | 11 (55) | 8 (40) | |
Gram-negative bacteria | - | 18 (90) | 15 (75) | |
Fungi | - | 11 (55) | 11 (55) | |
underlying diseases (n, %) | ||||
Hypertension | 6 (30) | 12 (30) | 6 (30) | 6 (30) |
Diabetes | 2 (10) | 7 (17.5) | 3 (15) | 4 (20) |
COPD | 0 (0) | 3 (7.5) | 3 (15) | 0 (0) |
Coronary heart disease | 3 (15) | 4 (10) | 2 (10) | 2 (10) |
Immunosuppressed | 0 (0) | 7 17.5) | 2 (10) | 5 (25) |
Nervous system disease | 0 (0) | 3 (7.5) | 2 (10) | 1 (5) |
CKD | 1 (5) | 7 (17.5) | 3 (15) | 2 (10) |