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Table 2 Crude and adjusted relative risk of plasma TNF-α for incident fractures

From: Pro-inflammatory cytokines and bone fractures in CKD patients. An exploratory single centre study

 

Hazard ratio and 95% CI associated to 5 pg/mL increase in plasma TNF-α for incident fractures

Crude

1.62 (1.05-2.50), P = 0.03

Adjusted for:

 

Age

1.64 (1.06-2.56), P = 0.03

Intact PTH

1.55 (1.03-2.35), P = 0.04

Sex

1.64 (1.06-2.54), P = 0.03

Previous fractures

1.61 (1.01-2.57), P = 0.04

Previous transplants

1.59 (1.05-2.40), P = 0.03

Risk Score

1.60 (1.04-2.45), P = 0.03

  1. Plasma TNF-α data were adjusted in bivariate Cox models including TNF-α and each risk factor listed. The latter factors were used to compute the risk score (see methods).