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Table 1 Clinical characteristics at the time of biopsy and follow-up in 218 pediatric patients with IgA nephropathy

From: Validation of the Oxford classification of IgA nephropathy for pediatric patients from China

  Current study Oxford study (Children) Shima et al. [19]
At time of biopsy n = 218 n = 59 n = 161
 Age (years) 14 (2–17.9) 13 (4–17.9) 11.7(3.6-19.4)
 Female 35% 25% 37%
 Hypertensive before biopsy 6.5% NA NA
 MAP (mm Hg) 88 ± 11 84 ± 10 79 ± 11
 eGFR (ml/min per 1.73 m2) 134 ± 42 120 ± 43 103 ± 30
 Proteinuria (g/day) 1.5(0.5-8.0) 2 (0.5-7.8) 0.7 (0.0–13.7)
 Previous macroscopic hematuria 57% 60% 66%
Follow-up
 Duration of follow-up (months) 56(12–182) 62 (20–268) 54 (12–170)
 50% decline in eGFR or ESRD 12.4% NA NA
 MAP (mm Hg) 86 ± 10 86 ± 8 NA
 Proteinuria (g/day) 0.6 (0.1-4.9) 0.9 (0.1–7.0) NA
 Immunosuppression 56% 48% 16%
 Prednisone 51% 48% 16%
 Others 28.6% 17% 11%
 Treated with RASB 61.5% 56% NA
  1. Abbreviations: RASB, renin-angiotensin system blockade; eGFR, estimated glomerular filtration rate; MAP, mean arterial pressure; ESRD, end stage renal disease; NA, not available.
  2. Values are expressed as mean ± s.d. or median (range). Calculation of MAP, eGFR, and proteinuria is detailed in the text.