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Table 1 Published reports of M fortuitum PD-peritonitis

From: Mycobacterium fortuitum as a cause of peritoneal dialysis-associated peritonitis: case report and review of the literature

Location of the report

Patient demographics

Time from admission to positive culture

Sensitivity

Directed Treatment

Tenckhoff removed

Comment

Houston, USA [1]

15 y/o male

4 days

S – Amikacin, trimethoprim/sulfamethoxazole, cefoxitin

IV Amikacin and IV cefoxitin. (c)

Yes

Abscess drainage required

R- doxycycline

Portland, USA [2]

57 y/o male

7 days

Not reported

PO Erythromycin, IV cephapirin, IV tobramycin.(6 days)

Yes

Catheter leak. No abdominal pain. Patient died at 6 days.

Copenhagen, Denmark [3]

35 y/o male

11 days

S – Amikacin, tobramycin, erythromycin, trimethoprim-sulfamethoxazole

IV Amikacin, IV methicillin (c)

Yes

In renal transplant perioperative period.

Cleveland, USA [4]

32 y/o male

6 days

S – Amikacin, tetracycline

Amikacin, tetracycline (1 month); ciprofloxacin (c, d)

Yes

Reduced aural acuity after amikacin.

R – gentamicin, tobramycin, erythromycin, trimethoprim/sulfamethoxazole

Hong Kong, China [5]

65 y/o male

-

Not reported

PO Levofloxacin, PO clarithromycin (12 months)

No

 

Seoul, Korea [6]

54 y/o female

7 days

R – isoniazid, rifampicin, ethambutol, streptomycin

IV Ceftizotime, IV amikacin (c)

Yes

 

Louisiana, USAb[7]

71 y/o male

7 days

Not reported

IP Amikacin and cefoxitin (3 weeks); PO doxycycline and rifampicin (3 months)

Yes

 

83 y/o female

4 days

Not reported

Ciprofloxacin and clofazimine (c, d)

?

Madrid, Spain [8]

42 y/o male

11 days

Not reported

IV Amikacin and PO doxycycline (20 days)

Yes

 

40 y/o male

8 days

Not reported

IV Amikacin and PO doxycycline (1 month)

Yes

Washington, USA [9]

33 y/o male

7 days

S – amikacin, kanamycin, clarithromycin, cefmetazole, imipenem, ciprofloxacin, ofloxacin, azithromycin

PO Clarithromycin and PO trimethoprim/sulfamethoxazole (6 months)

Yes

 

71 y/o female

4 days

R – tobramycin, erythromycin, doxycycline, minocycline, cefoxitin

IV Amikacin, PO clarithromycin, PO trimethoprim/sulfamethoxazole (3 months)

Yes

S – clarithromycin, cefmetazole, imipenem, sulfisoxazole, ciprofloxacin, ofloxacin

I – amikacin, cefoxitin

Saudi Arabia [10]

45 y/o female

7 days

 

PO Isoniazid, rifampicin, ethambutol. (6 months)

Yes

 

Nashville, USA [11]

16 y/o male

12 days

 

PO Ciprofloxacin, PO trimethoprim/sulfamethoxazole (c)

Yes

Perihepatic collection

Kfar-Saba, Israel [12]

65 y/o male

4 days

 

Minocycline (1 monthd)

Yes

Also bacteraemia

Tokyo, Japan [13]

50 y/o male

3 weeks

Not reported

Amikacin, sulbactam (c,d)

Yes

 

Singapore, Singapore b[14]

78 y/o female

8 days

S – tobramycin, linezolid, clarithromycin, amikacin

IP amikacin, PO ciprofloxacin (3 months)

No

Patient died at 2 months from malignancy

  1. aThis publication also reported on a suspected case of PD-peritonitis and two confirmed cases of Tenckhoff catheter exit site infections due to M. fortuitum.
  2. bThis publication also listed a second (male) patient with M. fortuitum PD-peritonitis in a table, but described the patient to be a female with M. abscessus PD-peritonitis in the text. Due to inconsistency in the report, this case was excluded.
  3. cDuration of therapy not known.
  4. dRoute of administration not known.
  5. IP intraperitoneal, PO per oral, IV intravenous.