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Table 1 Characteristics of patients classified by the index eGFR

From: Acute and acute-on-chronic kidney injury of patients with decompensated heart failure: impact on outcomes

 

Total cohort (n = 1005)

Index eGFR, ml/min/1.73 m2

  

≥60 (n = 738)

30 ~ 59 (n = 267)

P

Demographics

    

 Age, years

63 ± 16

60 ± 16

71 ± 12

<0.001

 Male, no. (%)

625(62.2)

461(62.5)

164(61.4)

0.763

 Current smoker, no. (%)

317(31.5)

240(32.5)

77(28.8)

0.267

Comorbid conditions

    

 Diabetes, no. (%)

368(36.6)

243(32.9)

125(46.8)

<0.001

 Hypertension, no. (%)

485(48.3)

304(41.2)

181(67.8)

<0.001

 Ischemic heart disease, no. (%)

506(50.3)

354(48.0)

152(56.9)

0.012

 Atrial fibrillation, no. (%)

288(28.7)

217(29.4)

71(26.6)

0.384

 Cerebrovascular disease, no. (%)

112(11.1)

71(9.6)

41(15.4)

0.011

 Comorbid sum a, no. (%)

   

<0.001

  0

118(11.7)

104(14.1)

14(5.2)

 

  1

305(30.3)

250(33.9)

55(20.6)

 

  2

347(34.5)

242(32.8)

105(39.4)

 

  ≥3

235(23.4)

142(19.2)

93(34.9)

 

Index eGFR, ml/min/1.73 m 2

78 ± 25

89 ± 18

47 ± 9

<0.001

Characteristics on admission

    

 LVEF < 45%, no. (%)

417(41.5)

305(41.3)

112(41.9)

0.860

 NYHA class 4, no. (%)b

467(46.5)

315(42.7)

152(56.9)

<0.001

 Systolic blood pressure, mm Hg

130 ± 20

127 ± 19

136 ± 23

<0.001

 Diastolic blood pressure, mm Hg

80 ± 22

79 ± 18

84 ± 30

0.002

 Serum creatinine, μmol/L

110 ± 64

90 ± 31

164 ± 95

<0.001

 Fasting plasma glucose, mmol/L

6.5 ± 2.3

6.4 ± 2.3

6.6 ± 2.6

0.385

 Serum triglyeride, mmol/L

1.5 ± 1.4

1.4 ± 1.3

1.6 ± 1.6

0.353

 Serum total cholesterol, mmol/L

4.6 ± 1.4

4.6 ± 1.4

4.6 ± 1.3

0.579

 Serum LDL-C, mmol/L

2.3 ± 1.0

2.4 ± 1.0

2.3 ± 1.0

0.564

 Serum albumin, g/L

36.2 ± 5.6

36.7 ± 5.2

34.6 ± 6.2

<0.001

 Haemoglobin, g/L

128 ± 23

131 ± 22

118 ± 24

<0.001

 Inotropic therapy, no. (%)

134(13.3)

104(14.1)

30(11.2)

0.239

  1. a Number of comorbid conditions in a patient.
  2. b NYHA class captured according to the manifestation during the first day of hospitalization.
  3. Abbreviation: AHF, acute heart failure; eGFR, estimated glomerular filtration rate; LDL-C, low density lipoprotein cholesterol; LVEF, left ventricular ejection fraction; NYHA, New York Heart Association.