Table 5 Selected dichotomized effects of IL12A rs568408 and IL18 rs360719 in hemodialysis patients with a titre of antibodies to surface antigen of hepatitis B virus ≤ 10 UI/L (Group I) and > 10 UI/L (Group II)
Variable | Group I (n = 207) n (%) | Group II (n = 311) n (%) | OR (95 % CI) | P value | Sample power (%) for significant differences |
|---|---|---|---|---|---|
Dichotomized genotypes of rs568408 and rs360719 | |||||
All other genotypes | 202 (97.6) | 294 (94.5) | 1.00 | ||
rs568408 GG and rs360719 CC | 5 (2.4) | 17 (5.5) | 0.43 (0.15 – 1.18) | 0.080 | |
All other genotypes | 185 (89.4) | 263 (84.6) | 1.00 | ||
rs568408 GA/AA and rs360719 TC/CC | 22 (10.6) | 48 (15.4) | 0.65 (0.38 – 1.12) | 0.112 | |
All other genotypes | 206 (99.5) | 303 (97.4) | 1.00 | ||
rs568408 GA and rs360719 CC | 1 (0.48) | 8 (2.6) | 0.18 (0.02 – 1.49) | 0.052 | |
rs568408 GA/AA and rs360719 CC | 1 (0.48) | 8 (2.6) | 0.18 (0.02 – 1.49) | 0.052 | |
All other genotypes | 200 (96.6) | 310 (99.7) | 1.00 | ||
rs568408 AA and rs360719 TT | 7 (3.4) | 1 (0.32) | 10.85 (1.32 – 89.30) | 0.005 | 75.2 |
All other genotypes | 202 (97.6) | 293 (94.2) | 1.00 | ||
rs3212227 AA and rs360719 CC | 5 (2.4) | 18 (5.8) | 0.40 (0.15 – 1.10) | 0.058 | |
All other genotypes | 206 (99.5) | 304 (97.7) | 1.00 | ||
rs3212227 AC and rs360719 CC | 1 (0.48) | 7 (2.3) | 0.21 (0.03 – 1.73) | 0.084 | |
All other genotypes | 206 (99.5) | 304 (97.7) | 1.00 | ||
rs3212227 AC/CC and rs360719 CC | 1 (0.48) | 7 (2.3) | 0.21 (0.03 – 1.73) | 0.084 | |
All other genotypes | 201 (97.1) | 309 (99.4) | 1.00 | ||
rs3212227 CC and rs360719 TC | 6 (2.9) | 2 (0.64) | 4.61 (0.92 - 23.16) | 0.042 | 52.6 |
All other genotypes | 201 (97.1) | 309 (99.4) | 1.00 | ||
rs3212227 CC and rs360719 TC/CC | 6 (2.9) | 2 (0.64) | 4.61 (0.92 - 23.16) | 0.042 | 52.6 |