Table 3 Comparison of subgroups according localization of CAC and AAC (mean & 95% CI)
AAC and CAC | Isolated AAC | No calcifications | ANOVA | |
|---|---|---|---|---|
(N = 76) | (N = 7) | (N = 19) | ||
Age (years) | 60 (57–63) | 48 (33–63) | 31 (27–34) | <0.001 |
Gender (male/female) | 41/35 | 4/3 | 10/9 | 0.95 |
Smoking (n /%) | 45 / 59.2 | 5 / 71.4 | 12 / 63.2 | 0.67 |
Diabetes (n /%) | 19 / 25.0 | 0 | 0 | 0.001 |
Hypertension (n /%) | 68 / 89.5 | 6 / 85.7 | 13 / 68.4 | 0.02 |
Coronary artery disease (n /%) | 33 / 42.3 | 2 / 28.6 | 0 | <0.001 |
Time on dialysis (months) | 45 (32–59) | 22 (10–34) | 36 (15–56) | 0.48 |
Kt/V | 1.30 (1.25-1.35) | 1.24 (0.93-1.54) | 1.31 (1.20-1.42) | 0.75 |
Body mass index (kg/m 2 ) | 25.2 (24.3-26.2) | 23.0 (18.9-27.2) | 23.1 (20.9-25.3) | 0.09 |
Hemoglobin (g/dL) | 11.1 (10.7-11.4) | 11.4 (10.4-12.5) | 11.0 (10.2-11.8) | 0.80 |
Albumin (g/dL) | 3.82 (3.70-3.94) | 3.75 (3.21-4.30) | 4.16 (3.91-4.29) | 0.08 |
Total cholesterol (mmol/L) | 4.78 (4.48-5.08) | 4.26 (3.90-4.61) | 4.08 (3.40-4.77) | 0.09 |
LDL cholesterol (mmol/L) | 2.75 (2.50-3.01) | 2.44 (1.91-2.98) | 2.19 (1.63-2.75) | 0.12 |
HDL cholesterol (mmol/L) | 1.16 (1.05-1.27) | 1.05 (0.89-1.21) | 1.11 (0.93-1.29) | 0.76 |
Triglycerides (mmol/L) | 2.00 (1.67-2.32) | 1.75 (0.94-2.56) | 1.52 (1.27-1.77) | 0.32 |
Dyslipidemia (n /%) | 57 / 75.0 | 3 / 42.9 | 13 / 68.4 | 0.37 |
Calcium (mmol/L) | 2.17 (2.13-2.21) | 2.22 (2.09-2.36) | 2.16 (2.07-2.25) | 0.68 |
Phosphorous (mmol/L) | 1.78 (1.62-1.94) | 1.94 (1.27-2.61) | 2.16 (1.78-2.54) | 0.12 |
Phosphorous >1.77 mmo/L (n /%) | 40 / 52.6 | 3 /42.9 | 14 /73.7 | 0.14 |
CaxP (mmol2/L2) | 3.84 (3.49-4.18) | 4.31 (2.26-5.77) | 4.64 (3.84-5.43) | 0.12 |
PTH (pg/mL) | 364 (263–464) | 310 (138–481) | 577 (225–928) | 0.22 |
PTH <100 pg/mL (n /%) | 20 / 25.6 | 0 | 2 / 10.5 | 0.06 |
25(OH)D3 (ng/mL) | 19.2 (14.2-24.2) | 24.2 (12.7-34.9) | 29.2 (17.4-40.9) | 0.04 |
iFGF-23 (ng/mL) | 638.0 (379.1-697.0) | 955.9 (0–2524.2) | 698.8 (363.5-1034.0) | 0.32 |
Osteocalcin (pmol/L) | 36.4 (26.7-46.0) | 32.3 (14.0-50.6) | 47.7 (25.7-69.7) | 0.50 |
Osteopontin (ng/mL) | 98.1 (86.8-109.4) | 124.4 (104.9-143.9) | 98.5 (80.3-116.7) | 0.31 |
Osteoprotegerin (pmol/L) | 17.5 (14.1-20.9) | 12.0 (3.7-20.3) | 6.4 (4.3-8.5) | 0.003 |
Matrix GLA protein (nmol/L) | 11.5 (10.5-12.5) | 9.1 (4.0-14.2) | 9.8 (7.9-11.8) | 0.13 |
Fetuin-A (g/L) | 0.60 (0.50-0.69) | 0.72 (0.39-1.05) | 0.68 (0.51-0.85) | 0.54 |
CRP (mg/L) | 12.9 (9.3-16.6) | 10.6 (7.2-18.1) | 8.2 (2.4-14.1) | 0.03 |
IL-6 (pg/mL) | 7.5 (5.3-9.6) | 6.8 (4.2-8.4) | 8.1 (1.0-15.3) | 0.68 |
TNF-α (pg/mL) | 11.1 (8.9-13.3) | 6.8 (2.5-9.7) | 11.4 (7.1-15.7) | 0.22 |