Figure 9
From: Bilirubin attenuates the renal tubular injury by inhibition of oxidative stress and apoptosis
Bilirubin (BIL) suppresses CsA-induced apoptosis in HK-2 cells. A: The protein expression of cleaved caspase-9 and cleaved caspse-3 from VH, CsA, BIL, and BIL+CsA groups in HK2 cells. B: The average densitometric ratio was calculated relative to β-actin for cleaved caspase-9. C: The protein expression of cleaved caspse-3 from VH, CsA, BIL, and BIL+CsA groups in HK2 cells. D: The average densitometric ratio was calculated relative to β-actin for cleaved caspase-3. E: Caspase-3 activity was determined by caspase-3 fluorometric assay in HK2 cells. The data are the means ± SD. *P<0.05 vs. control, †P<0.05 vs. CsA.