From: Bilirubin attenuates the renal tubular injury by inhibition of oxidative stress and apoptosis
 | VH | BIL | CsA | Bil + CsA |
---|---|---|---|---|
N | 5 | 5 | 5 | 5 |
Body weight (g) | 356.5 ± 29.0 | 356.1 ± 57.6 | 318.3 ± 57.6 | 290.6 ± 10.11 |
SBP (mmHg) | 127.5 ± 14.0 | 139.8 ± 10.0 | 149.0 ± 19.8 | 134.0 ± 15.9 |
Serum creatinine (mg/dL) | 0.7 ± 0.1 | 0.7 ± 0.2 | 1.7 ± 0.9*†| 1.7 ± 0.3*†|
24 hr urine albumin (mg) | 5.4 ± 4.1 | 4.8 ± 5.1 | 9.1 ± 6.5 | 6.6 ± 3.0 |
Serum CsA (μg/mL) | 0.02 ± 0.00 | 0.02 ± 0.00 | 2.89 ± 0.29*†| 3.31 ± 0.40*†|
Serum LDH (IU/L) | 486.6 ± 183.8 | 623.4 ± 400.1 | 748.2 ± 182.6 | 642.2 ± 193.6 |
Serum AST (IU/L) | 79.7 ± 18.9 | 86.2 ± 41.1 | 61.6 ± 6.1 | 66.0 ± 7.0 |
Serum ALT (IU/L) | 29.3 ± 3.8 | 34.0 ± 17.4 | 26.4 ± 3.6 | 31.0 ± 3.3 |
Serum bilirubin (mg/dL) | 0.03 ± 0.03 | 0.01 ± 0.02 | 0.16 ± 0.04*†| 00.20 ± 0.06*†|