B-type natriuretic peptide versus amino terminal pro-B type natriuretic peptide: selecting the optimal heart failure marker in patients with impaired kidney function

Table 3 Potential BNP and NT-proBNP cut off levels for the assessment of systolic heart failure for all CKD subjects

Natriuretic peptide	Group	Optimal cut point (pg/ml)	Sensitivity	Specificity	Positive likelihood ratio	Negative likelihood ratio
			%	%
BNP	Overall	217	64.2	70	1.04	0.96
BNP	Overall	254	61	75	1.14	0.90
BNP	Overall	300	55	82.1	3.05	0.55
NT-proBNP	Overall	799	91.6	52.6	1.99	0.16
NT-proBNP	Overall	1536	84.2	71.6	4.13	0.30
NT-proBNP	Overall	4502	73.7	82.1	4.17	0.30

Abbreviations: BNP B-type natriuretic peptide, NT-proBNP amino terminal B-type natriuretic peptide, AUC area under the curve, CKD chronic kidney disease.

ISSN: 1471-2369