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Table 3 Potential BNP and NT-proBNP cut off levels for the assessment of systolic heart failure for all CKD subjects

From: B-type natriuretic peptide versus amino terminal pro-B type natriuretic peptide: selecting the optimal heart failure marker in patients with impaired kidney function

Natriuretic peptide Group Optimal cut point (pg/ml) Sensitivity Specificity Positive likelihood ratio Negative likelihood ratio
    % %   
BNP Overall 217 64.2 70 1.04 0.96
BNP Overall 254 61 75 1.14 0.90
BNP Overall 300 55 82.1 3.05 0.55
NT-proBNP Overall 799 91.6 52.6 1.99 0.16
NT-proBNP Overall 1536 84.2 71.6 4.13 0.30
NT-proBNP Overall 4502 73.7 82.1 4.17 0.30
  1. Abbreviations: BNP B-type natriuretic peptide, NT-proBNP amino terminal B-type natriuretic peptide, AUC area under the curve, CKD chronic kidney disease.