Table 2 Baseline covariate effects on eGFR _creat using linear mixed effects model parameter estimates, 95% confidence intervals and p-values

Risk group (high vs. low)

1.57

(-1.49, 4.63)

0.313

Year

-0.93

(-1.34, -0.52)

<0.001

Risk group by year interaction

-1.74

(-2.56, -0.92)

<0.001

Diabetes duration

0.02

(-0.08, 0.12)

0.708

eGFR _creat

0.73

(0.69, 0.77)

<0.001

Urine albumin:creatinine ratio

-4.40

(-6.09, -2.71)

<0.001

Systolic BP

-0.08

(-0.14, -0.02)

0.010

Diastolic BP

0.13

(0.03, 0.23)

0.010

HbA1c

-0.65

(-1.30, 0.00)

0.046