Skip to main content

Table 2 Clinical characteristics of the genotyped diabetic nephropathy (DN) cases and diabetic controls

From: Haplotype association analysis of genes within the WNT signalling pathways in diabetic nephropathy

Characteristic DN Case (n = 700) Control (n = 732)
Male; n (%) 405 (57.8%) 306 (41.8%)
Age at diagnosis of T1D (yr) 14.7 ± 7.6 15.4 ± 7.9
Duration of T1D (yr)a 33 ± 9.3 28.1 ± 9
HbA1c (%)b 9 ± 1.9 8.6 ± 1.5
Systolic blood pressure (mmHg)b 144.9 ± 20.9 125.1 ± 14.8
Diastolic blood pressure (mmHg)b 81.5 ± 11.4 75.5 ± 7.7
Body mass index (kg/m2) 26.3 ± 4.8 26.1 ± 4.2
Serum cholesterol (mmol/L) 5.3 ± 1.2 5.1 ± 0.9
Serum creatinine (umol/L)c; median (interquartile range) 130 (102–182.5) 92 (78.8 - 105)
Glomerular filtration rate (ml/min/1.73m2)c; median (interquartile range) 47.8 (33.6 - 66.2) 70 (59.3 - 85.5)
End-stage renal disease n (%) 186 (26.6%) NA
  1. Unless otherwise stated values are mean ± standard deviation.
  2. aCalculated from the dates of diagnosis and recruitment.
  3. bAverage of the three most recent values prior to recruitment.
  4. cExcludes subjects receiving renal replacement therapy (dialysis or transplant).
  5. P < 0.05 for age at diagnosis; P <0.001 for all other comparisons except body mass index.
  6. T1D = type 1 diabetes.