The clinical status and survival in elderly dialysis: example of the oldest region of France

BMC Nephrology

Table 3 Adjusted hazard ratios of overall, 4-year mortality associated with study period (for all 214 patients over 75 years)

	Model-1			Mdel-2			Model-3			Model-4			Model-5
	Demographics			Demographics + Comorbidity			Demographics + Mobility			Demographics + Care			1 + 2 + 3 + 4
	HR	95% CI	p	HR	95% CI	p	HR	95% CI	p	HR	95% CI	p	HR	95% CI	p
Dialysis initiation year. reference:	2002-2004
2005-2007	0.81	0.69-0.95	0.010*	0.85	0.72-0,999	0.049*	0.88	0.74-1.06	NS	0.85	0.72-1.00	0.052	0.94	0.78-1.13	NS
Age. reference: 75–84 years
≥85 years	1.22	0.99-1.48	0.06	1.27	1.03-1.54	0.027*	1.18	0.95-1.44	NS	1.20	0.97-1.46	0.09	1.21	0.97-1.48	0.09
Gender. reference: Male
Female	0.99	0.84-1.17	NS	1.00	0.84-1.18	NS	0.95	0.80-1.13	NS	0.97	0.81-1.15	NS	0.96	0.80-1.15	NS
Comobidities. reference: without this comorbidity
Heart failure				1.31	1.11-1.55	0.001*							1.23	1.04-1.46	0.018*
Diabetes				1.21	1.02-1.43	0.030*							1.12	0.94-1.93	0.10
Mobility. reference: walk out help
Need assistance for transfers							1.43	1.16-1.74	<0.001*				1.40	1.13-1.71	0.002*
Tatally dependent for transfers							1.42	0.97-1.96	0.07				1.38	0.94-1.93	0.10
Dailysis modality. reference: HD with fistula
HD without fistula										1.29	1.03-1.62	0.025*	1.16	0.92-1.48	NS
PD										1.49	1.19-1.89	<0.001*	1.38	1.09-1.76	0.008*
Baseline eGFR. reference: 7 ≥ eGFR < 10 ml/min/1.73 m ²
eGFR < 7 ml/min/1.73 m²										1.08	0.88-1.33	NS	1.18	0.95-1.46	NS
eGFR ≥ 10 ml/min/1.73 m²										1.25	1.00-1.56	0.047*	1.36	1.08-1.71	0.009
Missing										1.13	0.79-1.55	NS	1.12	0.77-1.57	NS

HD hemodialysis, PD peritoneal dialysis, eGFR estimated glomerular filtration rate, HR hazard ratio, 95% CI 95% confidence intervals.
Model-1 was adjusted for age and gender.
Model-2 was adjusted as Model-1 + heart failure and diabetes.
Model-3 was adjusted as Model-1 + mobility.
Model-4 was adjusted as Model-1 + dialysis modality and baseline eGFR.
Model-5 was adjusted for all variables in previous models.
NS Not Significant (with p > 0.1).

ISSN: 1471-2369