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Table 2 Differences in variables according to tertiles of E/E

From: Diastolic dysfunction is associated with an increased risk of contrast-induced nephropathy: a retrospective cohort study

Variables

E/E’ ≤ 8

8 < E/E’ ≤ 15

E/E’ > 15

p

(n = 47)

(n = 494)

(n = 194)

Age (years)

57.0 ± 9.5

63.4 ± 10.3

70.1 ± 9.6

0.036

Sex (male)

42 (89.4%)

375 (75.9%)

97 (50.0%)

<0.001

BMI (kg/m2)

23.7 ± 2.3

24.7 ± 3.3

24.4 ± 3.6

0.061

Systolic BP (mmHg)

115.3 ± 13.6

119.9 ± 14.0

119.9 ± 17.9

0.018

Diastolic BP (mmHg)

71.3 ± 9.4

72.6 ± 9.4

70.4 ± 10.8

0.150

Hypertension

21 (44.7%)

305 (61.7%)

149 (76.8%)

<0.001

Diabetes mellitus

12 (25.5%)

154 (31.2%)

84 (43.3%)

0.005

Previous CABG

0 (0.0%)

13 (2.6%)

10 (5.2%)

0.130

Emergency/ urgent procedure

5 (10.6%)

103 (20.9%)

52 (26.8%)

0.038

Interventional strategy

   

0.680

 Ballooning

1 (2.1%)

14 (2.8%)

8 (4.1%)

 

 Ballooning + Stent insertion

42 (89.4%)

415 (84.0%)

157 (80.9%)

 

 Ballooning + Stent insertion + Thrombus suction

4 (8.5%)

65 (13.2%)

29 (14.9%)

 

3-vessel disease

12 (25.5%)

134 (27.1%)

95 (49.0%)

<0.001

Hypotensive event

3 (6.4%)

45 (9.1%)

42 (21.6%)

<0.001

IABP use

0 (0.0%)

11 (2.2%)

21 (10.8%)

<0.001

Total volume of CM (mL)

236.6 ± 89.4

237.9 ± 75.0

234.6 ± 69.1

0.956

Volume of CM per weight (mL/kg)

3.53 ± 1.19

3.62 ± 1.22

3.92 ± 1.53

0.176

N-acetylcysteine

24 (25.3%)

144 (33.2%)

65 (39.2%)

0.071

CIN

2 (4.3%)

20 (4.0%)

42 (21.6%)

<0.001

BUN (mg/dL)

15.6 ± 3.5

17.3 ± 6.3

20.2 ± 9.6

0.112

Creatinine (mg/dL)

1.02 ± 0.25

1.04 ± 0.32

1.21 ± 0.57

0.848

eGFR (mL/min/1.73m2)

82.9 ± 17.9

77.4 ± 18.7

64.9 ± 22.4

0.071

Hemoglobin (g/dL)

13.9 ± 1.3

13.4 ± 1.7

12.3 ± 1.9

0.058

Albumin (g/dL)

4.45 ± 0.43

4.39 ± 0.41

4.06 ± 0.54

0.308

hs-CRP (mg/L)

6.85 ± 29.80

7.67 ± 24.10

17.20 ± 36.50

<0.001

Cholesterol (mg/dL)

161.7 ± 42.7

164.6 ± 42.9

165.4 ± 45.7

0.570

Triglyceride (mg/dL)

143.9 ± 95.3

142.5 ± 85.1

132.4 ± 70.4

0.742

Glucose (mg/dL)

116.6 ± 41.3

121.8 ± 41.6

133.7 ± 56.6

0.205

Ejection fraction (%)

61.0 ± 10.0

59.4 ± 12.1

52.7 ± 14.4

0.578

E/E'

6.7 ± 0.8

11.2 ± 2.1

20.4 ± 4.9

<0.001

E/A

0.98 ± 0.38

0.90 ± 0.50

1.01 ± 0.44

0.065

Deceleration time (ms)

207.5 ± 46.1

207.9 ± 49.5

195.6 ± 52.0

0.699

LV mass (g)

188.6 ± 41.6

212.1 ± 108.2

223.6 ± 64.5

0.014

LV mass index (g/m2)

107.2 ± 22.6

121.5 ± 57.0

143.5 ± 145.8

0.003

LVDd (mm)

48.4 ± 3.5

49.8 ± 4.7

50.8 ± 5.8

0.014

LA volume index (mL/m2)

22.3 ± 4.8

26.6 ± 7.9

34.1 ± 11.9

<0.001

  1. Abbreviations: BMI body mass index; BP blood pressure; BUN blood urea nitrogen; CABG coronary artery bypass graft; CIN contrast-induced nephropathy; CM contrast media; eGFR estimated glomerular filtration rate; hs-CRP high sensitivity C-reactive protein; IABP intra-aortic balloon pump; LA left atrium; LV left ventricle; LVDd left ventricular end-diastolic dimension.