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Table 1 Demographic, listing, and peri-transplant characteristics in patients with pre-OLT renal dysfunction that are associated with recovery of renal function post-OLT

From: Predictors of renal recovery in patients with pre-orthotopic liver transplant (OLT) renal dysfunction

 

Recovery of renal function (n=863)

Non-recovery (n=857)

p

OR (95% CI)

Demographic characteristics

    

Age

50.3 ± 10.2

50.0 ± 10.5

0.3

 

Sex (male)

544 (63%)

581 (67%)

0.043

0.81 (0.66-0.98)

Race (Caucasian)

599 (70%)

620 (72%)

0.21

0.88 (0.70-1.07)

Listing characteristics

    

ICU admission

207 (24%)

255 (29%)

0.007

0.74 (0.60-0.92)

Mechanical ventilation

108 (13%)

172 (20%)

0.00001

0.57 (0.43-0.74)

Encephalopathy

510 (59%)

541 (60%)

0.35

1.08 (0.9-1.3)

Ascites

593 (72%)

598 (63%)

0.60

0.95 (0.75-1.16)

TIPS

57 (6.6%)

63 (7%)

0.63

0.92 (0.65-1.30)

PVT

17 (1.9%)

30 (3.5%)

0.052

0.55 (0.32-0.93)

Dialysis (at listing)*

248 (28%)

303 (32%)

0.003

0.63 (0.50-0.76)

BMI (kg/m2)

27.6 ± 5.5

28.4 ± 6.1

0.02

 

Peri-transplant characteristics

    

Wait time from listing (days)

178 ± 297

145 ± 266

0.00001

 

ICU admission

441 (51%)

417 (49%)

0.76

1.03 (0.85-1.20

Mechanical ventilation

206 (24%)

249 (29%)

0.015

0.76 (0.62-0.95)

Encephalopathy

343 40%)

344 (41%)

0.86

0.98 (0.81-1.20)

Ascites

580 (67%)

547 (64%)

0.14

1.20 (0.95-1.40)

TIPS

75 (8.6%)

79 (9.2%)

0.70

0.93 (0.67-1.30)

PVT

22 (2.5%)

39 (4.5%)

0.025

0.55 (0.32-0.99)

Dialysis (at transplant)*

421 (49%)

471 (55%)

0.01

0.70 (0.57-0.85)

Dialysis (at both listing and transplant)

169 (19%)

204 (23%)

0.03

0.78 (0.62-0.99)

BMI (kg/m2)

27.0 ± 6.4

28.0 ± 6.3

0.019

 
  1. Abbreviations: BMI body mass index, CI confidence interval, ICU intensive care unit, OLT orthotopic liver transplant, OR odds ratio, PVT portal vein thrombosis, TIPS transjugular intrahepatic porto-systemic shunt.
  2. * The number of patients on dialysis at listing (n = 551) includes those on dialysis only at listing (n = 178) as well as those on dialysis at both listing and transplant (n = 373). Similarly, the number of patients on dialysis at transplant (n = 892) includes those on dialysis only at listing (n = 519) as well as those on dialysis at both listing and transplant (n = 373).