Changes in the histological spectrum of glomerular diseases in the past 16 years in the North-Eastern region of Romania

Table 3 Incidence of different forms of primary glomerulonephritis

	MPGN % (p.m.p/year)	MesGN % (p.m.p/year)	MN % (p.m.p/year)	CGN % (p.m.p/year)	FSGS % (p.m.p/year)	MCD % (p.m.p/year)
Iasi, Romania (1995–2010)
Period 1, N=172	38.4 (1.39)	18.6 (0.67)	13.9 (0.51)	12.2 (0.44)	11.1 (0.40)	5.8 (0.21)
Period 2, N=116	29.3^a (1.19)	13.8 (0.56)	27.6^a (1.13)	9.5 (0.37)	17.2 (0.70)	2.6 (0.11)
Overall N=288	34.7^b (1.31)	16.6^b (0.63)	19.5^b (0.74)	11.2^b (0.42)	13.5 (0.51)	4.5 (0.17)
IRRB[6], N=6990	6.6 (1.62)	43.5 (10.67)	23.4 (5.73)	2.3 (0.57)	13.1 (3.23)	9.2 (2.25)
CRRB[17], N= 2333	4.6 (1.49)	45.8 (14.82)	9.3 (3.01)	3.2 (1.04)	10.8 (3.37)	12.5 (4.04)
SRRB[7], N=955; <60 years (%)	10.0	37.3	18.9	5.1	18.9	7.8
SRRB[7], N=87; ≥60 years (%)	16.1	24.0	28.7	6.9	18.4	4.6
SRRB[7], N=1042; all ages (renal biopsies/per million population (p.m.p.)/year)	0.73	2.51	1.37	0.37	1.31	0.53

CGN - crescentic glomerulonephritis); FSGS - focal segmental glomerulosclerosis; MCD - minimal change disease; MesGN - mesangioproliferative glomerulonephritis (including IgAN); MN - membranous nephropathy; MPGN - membranoproliferative glomerulonephritis. IRRB - Italian Registry of Renal Biopsies; CRRB - Czech Registry of Renal Biopsies; SRRB - Serbian Registry of Renal Biopsies.
^asignificant differences between period 1 and period 2 (p<0.05).
^bsignificant differences between Iasi vs. IRRB vs. CRRB vs. SRRB (p<0.05).
Data are expressed in percentage and as renal biopsies /per million population (p.m.p.)/year.

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