Baseline characteristics and prevalence of cardiovascular disease in newly visiting or referred chronic kidney disease patients to nephrology centers in Japan: a prospective cohort study

Table 4 Comparison of baseline characteristics of CKD cohort studies

	ROUTE	CRIC [20],[21]	CRISIS [22]	MERENA [23]
	Japan	US	UK	Spain
	n = 1138	n = 3612	n = 1325	n = 1129
eGFR (ml/min per 1.73 m²)	0 - 90	20 - 70	10 - 60	15 - 60
Age (years)	68	58.2	65.1	68
Male gender (%)	69.6	54	63.7	64
BMI (kg/m²)	23	32.1		28.4
eGFR (ml/min per 1.73 m²)	32.7	43.4	30.9	28
Diabetes (%)	37.1	47	32.4	40.8
Hypertension (%)	90.2	86		92.7
SBP (mmHg)	140	127.7	138.3	141
DBP (mmHg)	78	71.4	75.2	76
ARB or ACEI (%)	63	68	59.8
Hb (g/dl)	11.9	12.7	12.41	12.8
LDL-C (mg/dl)	110	102.5		116
Ca (mg/dl)	9.1	9.2	9.14
P (mg/dl)	3.6	3.7	3.72	3.7
Intact PTH (pg/ml)	109	53	93.2	145
Prevalence of CVD (%)	26.8	33.4	47.2	39.1
Proteinuria (mean)	2.16 g/gCr		1.08 g/day	1.2 g/day
Proteinuria (median)	0.74 g/gCr	0.17 g/day

BMI body mass index, eGFR estimated glomerular filtration rate, SBP systolic blood pressure, DBP diastolic blood pressure, ARB angiotensin receptor blockers, ACEI angiotensin converting enzyme inhibitors, Hb hemoglobin, LDL-C low density lipoprotein cholesterol, Ca calcium, P phosphorus, PTH parathyroid hormone, CVD cardiovascular disease, g/gCr gram per gram creatinine.

ISSN: 1471-2369