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Table 4 Comparison of baseline characteristics of CKD cohort studies

From: Baseline characteristics and prevalence of cardiovascular disease in newly visiting or referred chronic kidney disease patients to nephrology centers in Japan: a prospective cohort study

  ROUTE CRIC [20],[21] CRISIS [22] MERENA [23]
  Japan US UK Spain
  n = 1138 n = 3612 n = 1325 n = 1129
eGFR (ml/min per 1.73 m2) 0 - 90 20 - 70 10 - 60 15 - 60
Age (years) 68 58.2 65.1 68
Male gender (%) 69.6 54 63.7 64
BMI (kg/m2) 23 32.1   28.4
eGFR (ml/min per 1.73 m2) 32.7 43.4 30.9 28
Diabetes (%) 37.1 47 32.4 40.8
Hypertension (%) 90.2 86   92.7
SBP (mmHg) 140 127.7 138.3 141
DBP (mmHg) 78 71.4 75.2 76
ARB or ACEI (%) 63 68 59.8  
Hb (g/dl) 11.9 12.7 12.41 12.8
LDL-C (mg/dl) 110 102.5   116
Ca (mg/dl) 9.1 9.2 9.14  
P (mg/dl) 3.6 3.7 3.72 3.7
Intact PTH (pg/ml) 109 53 93.2 145
Prevalence of CVD (%) 26.8 33.4 47.2 39.1
Proteinuria (mean) 2.16 g/gCr   1.08 g/day 1.2 g/day
Proteinuria (median) 0.74 g/gCr 0.17 g/day   
  1. BMI body mass index, eGFR estimated glomerular filtration rate, SBP systolic blood pressure, DBP diastolic blood pressure, ARB angiotensin receptor blockers, ACEI angiotensin converting enzyme inhibitors, Hb hemoglobin, LDL-C low density lipoprotein cholesterol, Ca calcium, P phosphorus, PTH parathyroid hormone, CVD cardiovascular disease, g/gCr gram per gram creatinine.