Table 1 Demographic and laboratory data of the two age groups
Total (n=5008) | Age-groups (years) | Comparison of groups | |||
|---|---|---|---|---|---|
I. <65 (n=2413) | II. ≥65 (n=2595) | ||||
Age (year) | 63.4 ± 14.2 | 51.5 ± 10.1 | 74.5±6.3 | - | |
Gender (%) | Male | 2644 (52.8%) | 1418 (58.8%) | 1226 (47.2%) | p<0.001 |
Female | 2364 (47.2%) | 995 (41.2%) | 1369 (52.8%) | ||
BMI (kg/m2) | Male | 26.8 ± 5,2 | 27.0 ± 5.7 | 26.7 ± 4.6 | NS |
Female | 26.4 ± 6,1 | 26.4 ± 7.0 | 26.4 ± 5.4 | NS | |
Dialysis modality (%) | PD | 569 (11.4% ) | 341 (14.1%) | 228 (8.9%) | p<0.001 |
HD | 4439 (88.6%) | 2072 (85.9%) | 2367 (91.2%) | ||
intact PTH (pg/ml) (median, quartiles) | 178.0 75.8–361.5 | 206.0 82.2–451.0 | 157.0 70.0–30.2 | p<0.001 | |
intact PTH (pg/ml) (geometric mean, 95% CI of mean) | 158.7 153.5–169.1 | 184.9 175.7–194.6 | 136.7 131.6–143.8 | p<0.001 | |
Calcium (mmol/l) | 2.25 ± 0.19 | 2.24 ± 0.21 | 2.26 ± 0.17 | p<0.001 | |
Phosphate (mmol/l) | 1.50 ± 0.49 | 1.63 ± 0.50 | 1.39 ± 0.43 | p<0.001 | |
CaxP (mmol2/l2) | 3.38 ± 1.10 | 3.63 ± 1.15 | 3.14 ± 0.99 | p<0.001 | |
Albumin (g/l) | 39.4 ± 4.2 | 39.9 ± 4,3 | 38.9 ± 4.1 | p<0.001 | |
Diabetes mellitus (%) | 1641 (32.8%) | 658 (27.3%) | 983 (37.9%) | p<0.001 | |
Bone disease (%) | 1935 (38.6%) | 822 (34.1%) | 1113 (42.9%) | p<0.001 | |
Soft tissue calcification (%) | 2540 (50.7%) | 1078 (44.7%) | 1462 (56.3%) | p<0.001 | |
Parathyroidectomy (%) | 104 (2.1%) | 84 (3.5%) | 20 (0.8%) | p<0.001 | |
Cause of ESRD | Glomerulonephritis | 813 (16.2%) | 524 (21.7%) | 289 (11.1%) | p<0.001 |
Tubulointerstitial | 695 (13.9%) | 293 (12.1%) | 402 (15.5%) | p<0.001 | |
Diabetes mellitus | 1105 (22.1%) | 455 (18.9%) | 650 (25.1%) | p<0.001 | |
Hypertension | 1146 (22.9%) | 464 (19.2%) | 682 (26.3%) | p<0.001 | |
Polycystic | 379 (7.6%) | 238 (9.9%) | 141 (5.4%) | p<0.001 | |
Unknown | 189 (3.8%) | 99 (4.1%) | 90 (3.5%) | NS | |
other | 681 (13.6%) | 340 (14.1%) | 341 (13.1%) | NS | |
Prescribed therapy (%) | Calcimimetic | 259 (5.2%) | 196 (8.1%) | 63 (2.4%) | p<0.001 |
Ca based PO4-binder | 2011 (40.2%) | 1033 (42.8%) | 978 (37.7%) | p<0.001 | |
Non-Ca based PO4-binder | 947 (18.9%) | 626 (25.9%) | 321 (12.4%) | p<0.001 | |
Native vitamin D | 166 (3.3%) | 89 (3.7%) | 77 (3.0%) | NS | |
Active vitamin D | 2020 (40.4%) | 1037 (43%) | 983 (37.9%) | p<0.001 | |
None | 1349 (26.9%) | 489 (20.3%) | 860 (33.1%) | p<0.001 | |