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Table 1 Demographic and laboratory data of the two age groups

From: Age-dependent parathormone levels and different CKD-MBD treatment practices of dialysis patients in Hungary - results from a nationwide clinical audit

  Total (n=5008) Age-groups (years) Comparison of groups
  I. <65 (n=2413) II. ≥65 (n=2595)  
Age (year)   63.4 ± 14.2 51.5 ± 10.1 74.5±6.3 -
Gender (%) Male 2644 (52.8%) 1418 (58.8%) 1226 (47.2%) p<0.001
  Female 2364 (47.2%) 995 (41.2%) 1369 (52.8%)  
BMI (kg/m2) Male 26.8 ± 5,2 27.0 ± 5.7 26.7 ± 4.6 NS
  Female 26.4 ± 6,1 26.4 ± 7.0 26.4 ± 5.4 NS
Dialysis modality (%) PD 569 (11.4% ) 341 (14.1%) 228 (8.9%) p<0.001
  HD 4439 (88.6%) 2072 (85.9%) 2367 (91.2%)  
intact PTH (pg/ml) (median, quartiles) 178.0 75.8–361.5 206.0 82.2–451.0 157.0 70.0–30.2 p<0.001
intact PTH (pg/ml) (geometric mean, 95% CI of mean) 158.7 153.5–169.1 184.9 175.7–194.6 136.7 131.6–143.8 p<0.001
Calcium (mmol/l) 2.25 ± 0.19 2.24 ± 0.21 2.26 ± 0.17 p<0.001
Phosphate (mmol/l) 1.50 ± 0.49 1.63 ± 0.50 1.39 ± 0.43 p<0.001
CaxP (mmol2/l2) 3.38 ± 1.10 3.63 ± 1.15 3.14 ± 0.99 p<0.001
Albumin (g/l) 39.4 ± 4.2 39.9 ± 4,3 38.9 ± 4.1 p<0.001
Diabetes mellitus (%) 1641 (32.8%) 658 (27.3%) 983 (37.9%) p<0.001
Bone disease (%) 1935 (38.6%) 822 (34.1%) 1113 (42.9%) p<0.001
Soft tissue calcification (%) 2540 (50.7%) 1078 (44.7%) 1462 (56.3%) p<0.001
Parathyroidectomy (%) 104 (2.1%) 84 (3.5%) 20 (0.8%) p<0.001
Cause of ESRD Glomerulonephritis 813 (16.2%) 524 (21.7%) 289 (11.1%) p<0.001
  Tubulointerstitial 695 (13.9%) 293 (12.1%) 402 (15.5%) p<0.001
  Diabetes mellitus 1105 (22.1%) 455 (18.9%) 650 (25.1%) p<0.001
  Hypertension 1146 (22.9%) 464 (19.2%) 682 (26.3%) p<0.001
  Polycystic 379 (7.6%) 238 (9.9%) 141 (5.4%) p<0.001
  Unknown 189 (3.8%) 99 (4.1%) 90 (3.5%) NS
  other 681 (13.6%) 340 (14.1%) 341 (13.1%) NS
Prescribed therapy (%) Calcimimetic 259 (5.2%) 196 (8.1%) 63 (2.4%) p<0.001
  Ca based PO4-binder 2011 (40.2%) 1033 (42.8%) 978 (37.7%) p<0.001
  Non-Ca based PO4-binder 947 (18.9%) 626 (25.9%) 321 (12.4%) p<0.001
  Native vitamin D 166 (3.3%) 89 (3.7%) 77 (3.0%) NS
  Active vitamin D 2020 (40.4%) 1037 (43%) 983 (37.9%) p<0.001
  None 1349 (26.9%) 489 (20.3%) 860 (33.1%) p<0.001
  1. NS non-significant.