Table 2 Results of the linear regression analyses as well the Bland-Altman-analyses of the creatinine-based eGFR values (dependent variable) versus the kinetically determined mGFR values (95% confidence intervals in parentheses)
eGFR Variable | Total mGFR range | mGFR <= 60 (mL/min)/1.73 m2 | mGFR > 60 (mL/min)/1.73 m2 | 60 < mGFR <= 90 (mL/min)/1.73 m2 | mGFR > 90 (mL/min)/1.73 m2 | |
|---|---|---|---|---|---|---|
CKD-EPI | Intercept | 14.7 (6.9 – 22.4) | −9.8 (-29.5 – 9.9) | 34.7 (20.5 – 48.9) | 1.7 (-44.8 – 48.2) | 64.9 (41.3 – 88.2) |
Slope | 0.67 (0.59 – 0.75) | 1.13 (0.71 – 1.55) | 0.49 (0.36 – 0.62) | 0.86 (0.25 – 1.47) | 0.24 (0.04 – 0.44) | |
R* | 0.78 (0.71 – 0.83) | 0.66 (0.44 – 0.80) | 0.55 (0.42 – 0.66) | 0.47 (0.14 – 0.71) | 0.23 (0.03 – 0.41) | |
Bias+ | 14.8 (11.8 – 17.9) | 3.8 (-1.3 – 8.9) | 18.4 (14.8 – 21.9) | 8.6 (3.2 – 14.1) | 21.5 (17.3 – 25.7) | |
Limits of agreement | −24.9 – 54.6 | −27.9 – 35.6 | −21.4 – 51.9) | −20.2 – 37.6 | −19.3 – 62.2 | |
MDRD | Intercept | 14.9 (7.0 – 22.9) | −6.7 (-24.4 – 11.0) | 34.7 (19.0 – 49.1) | 10.4 (-30.2 – 51.1) | 61.3 (35.4 – 87.2) |
Slope | 0.64 (0.55 – 0.72) | 1.03 (0.66 – 1.41) | 0.46 (0.32 – 0.60) | 0.72 (0.18 – 1.25) | 0.24 (0.01 – 0.46) | |
R | 0.76 (0.69 – 0.82) | 0.67 (0.46 – 0.81) | 0.50 (0.36 – 0.62) | 0.45 (0.11 – 0.69) | 0.21 (0.01 – 0.3) | |
Bias | 17.9 (14.7 – 21.1) | 5.2 (0.6 – 9.7) | 22.0 (18.2 – 25.7) | 11.1 (6.3 – 15.9) | 25.4 (20.9 – 29.9) | |
Limits of agreement | −23.5 – 59.3 | −23.1 – 33.5 | −19.9 – 63.9 | −14.6 – 36.9 | −18.4 – 69.3 | |