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Table 3 Assessment of exercise tolerance (cardiopulmonary exercise test and six-minute walk test)

From: Pulmonary function and exercise tolerance are related to disease severity in pre-dialytic patients with chronic kidney disease: a cross-sectional study

Variables Control Stage 3 Stage 4 Stage 5 P
  (CG = 9) (G3 = 10) (G4 = 10) (G5 = 9)  
Cardiopulmonary test      
RPmax (W/kg) 4.9 ± 1.3 3.7 ± 0.9a 3.0 ± 1.2a 3.2 ± 1.0a 0.007
VO2peak (mL/kg/min) 28.9 ± 7.8 23.3 ± 5.6 21.4 ± 5.2a 20.2 ± 6.9a 0.033
VO2peak (%) 85.4 ± 18.2 75.8 ± 18.3 65.9 ± 16.0a 63.4 ± 16.0a 0.038
VO2AT (mL/kg/min) 20.5 ± 4.1 15.7 ± 3.5a 16.6 ± 3.8a 13.6 ± 3.8a 0.005
VEmax (l/min) 68.2 ± 20.3 60.8 ± 20 49.7 ± 20 56.9 ± 28.9 0.356
HRmax (bpm) 165 ± 14 146 ± 16a 139 ± 23a 129 ± 18a 0.003
HRmax (%) 97.9 ± 34.6 90.0 ± 11.1 82.8 ± 11.5a 79.3 ± 9.9a 0.003
SBPmax (mmHg) 197.5 ± 34.6 202.6 ± 25.8 204.2 ± 35.5 201.7 ± 34.3 0.976
DPBmax (mmHg) 89.7 ± 7.5 97.6 ± 9.2 101.8 ± 18.7 98.8 ± 9.6 0.203
6MWT      
Distance (m) 627.6 ± 37.8 577.4 ± 66.1 542 ± 57.3a 531.5 ± 84.2a 0.012
% Predicted (%) 90.5 ± 7.6 93.9 ± 7.5 83.4 ± 9.5b 83.0 ± 8.9b 0.017
  1. RPmax Maximum Relative Power, VO 2 peak Peak Oxygen Consumption, VO 2 AT Oxygen Consumption at Anaerobic Threshold, VE Minute Ventalation, HRmax Maximum Heart Rate, SBPmax Maximum Systolic Blood Pressure, DBPmax Maximum Diastolic Blood Pressure.
  2. Post hoc analysis: a = differs from CG at p<0.05; b = differs from G3 at p<0.05.