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Table 1 Baseline demographic characteristics of the 4 groups of patients

From: Increasing high-sensitive C-reactive protein level predicts peritonitis risk in chronic peritoneal dialysis patients

 

Group 1

Group 2

Group 3

Group 4

 

n = 171

n = 45

n = 31

n = 80

Demographic factors

    

 Mean age at the start of the study

48

51

49

55

 (range)

(18–83)

(20–80)

(27–67)

(24–80)

 Male, %

39

44

52

52

 Diabetes, %

7.0

6.7

25.8e

22.8e

 PD vintage, years

4.6 ± 3.2

5.5 ± 3.7

4.1 ± 2.9

5.3 ± 3.1

 Kt/V urea (Gotch formula)

2.14 ± 0.46

2.11 ± 0.35

2.03 ± 0.39

2.02 ± 0.33

 nPCR, g/day

1.11 ± 0.23a

1.08 ± 0.22

1.02 ± 0.23

1.00 ± 0.24

 Body mass index, kg/m2

21.9 ± 3.5b

22.8 ± 3.9

24.0 ± 3.0

24.3 ± 3.8

Clinical co-morbidity, %

    

  Coronary artery disease

2

2

0

3

  Congestive heart failure

6

7

3

9

  Peripheral vascular disease

2

0

3

11

  Stroke

2

4

10

9

  Neoplasm

8

18

0

5

  Chronic lung disease

5

2

6

8

  Liver cirrhosis or hepatoma

3

0

10

4

No comorbidity, %

74

73

81

76

Recurrent peritonitis, %

5

9

0

6

Hospitalized stay, day

5 ± 11a

9 ± 14

8 ± 11

12 ± 21

Laboratory data

    

  Baseline albumin, g/dL

3.80 ± 0.38

3.79 ± 0.39

3.68 ± 0.50

3.68 ± 0.42

  Final albumin, g/dL

3.83 ± 0.35a,c

3.66 ± 0.39

3.87 ± 0.40

3.67 ± 0.43

  ∆ albumin, %

1% ± 7%c

−3% ± 9%

6% ± 12% a,c

0% ± 11%

  Baseline hs-CRP, mg/L,

1.49

2.10 f

9.75 g

11.6g

  (Q1–Q3)

(0.84 to 2.25)

(1.30 to 3.61)

(7.30 to 16.1)

(7.85 to17.8)

  Final hs-CRP, mg/L,

1.45

9.20 g

2.49f

12.8g

  (Q1–Q3)

(0.74 to 2.39)

(7.29 to 12.1)

(1.36 to 3.71)

(7.89 to 25.1)

  ∆ hs-CRP, %

−6h

416

−80h

0h

  (Q1–Q3)

(−38 to 49)

(1.78 to 7.02)

(−91 to −59)

(−29 to 69)

  Hematocrit, %

32.2 ± 4.3c

29.7 ± 4.6

30.9 ± 3.9

30.7 ± 4.0

  Serum cholesterol, mg/dl

185 ± 39

177 ± 42

196 ± 59

184 ± 39

  Serum triglyceride, mg/dL

145 ± 83

138 ± 93

158 ± 109

174 ± 93

  Serum K, mEq/L

4.1 ± 0.7b

4.0 ± 0.6

3.9 ± 0.8

3.7 ± 0.6

  BUN, mg/dL

66 ± 17

72 ± 19

62 ± 16

64 ± 15c

  Serum Cr, mg/dL

12.1 ± 2.8

11.8 ± 3.0

11.6 ± 3.5

11.2 ± 2.6

  Serum phosphorus, mg/dL

5.2 ± 1.1

5.6 ± 1.5

5.4 ± 1.5

5.0 ± 1.2c

  Serum calcium, mg/dL

9.3 ± 0.8

9.3 ± 0.8

9.1 ± 0.9

9.4 ± 0.8

  1. Abbreviations: PD peritoneal dialysis, nPCR normalized protein catabolism rate, BUN blood urea nitrogen, Cr creatinine.
  2. Statistics:
  3. ap < 0.05, bp < 0.001 vs. group 4 (ANOVA with Bonferroni tests), cp < 0.05, vs. group 2 (ANOVA with Bonferroni tests), ep < 0.05 vs. group 2 (Chi square tests), fp < 0.05, gp < 0.001 vs. group 1 (Kruskal–Wallis one-way analysis of variance), hp < 0.001 vs. group 2 (Kruskal–Wallis one-way analysis of variance).