Association between family members of dialysis patients and chronic kidney disease: a multicenter study in China

BMC Nephrology

Table 2 Unadjusted and adjusted odds ratio for indicators of kidney damage in the pooled database

Variables	Spouses (vs. controls)^*	Relatives (vs. controls)^†
Albuminuria
Unadjusted OR (95% CI)	1.19 (0.87 – 1.62)	1.83 (1.45 – 2.31)
Age- and sex-adjusted OR (95% CI)	1.18 (0.86 – 1.62)	1.84 (1.45 – 2.32)
Multivariable adjusted OR (95% CI)	1.28 (0.92 – 1.77)^‡	2.02 (1.57 – 2.59)^§
Decreased eGFR
Unadjusted OR (95% CI)	0.47 (0.27 – 0.80)	0.63 (0.36 – 1.11)
Age- and sex-adjusted OR (95% CI)	0.46 (0.27 – 0.80)	0.64 (0.36 – 1.13)
Multivariable adjusted OR (95% CI)	0.50 (0.28 – 0.88)^§	0.68 (0.38 – 1.21) ^‡
CKD
Unadjusted OR (95% CI)	0.92 (0.69 – 1.23)	1.46 (1.17 – 1.82)
Age- and sex-adjusted OR (95% CI)	0.91 (0.67 – 1.22)	1.47 (1.17 – 1.83)
Multivariable adjusted OR (95% CI)	0.98 (0.72 – 1.33) ^‡	1.58 (1.25 – 2.0)^§

Abbreviations: CKD, chronic kidney disease; OR, odds ratio; estimated glomerular filtration rate; CI, confidence interval.
^* Pooled database including data of spouses and their counterpart controls.
^† Pooled database including data of relatives and their counterpart controls.
^‡ORs were adjusted for age, gender, hypertension, diabetes.
^§ORs were adjusted for age, gender, hypertension, diabetes, nephrotoxic medications, chronic respiratory tract infection, overweight, dyslipidemia, education (≥high school).

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