Table 1 Characteristics of the 13 clinical trials (17 patient groups) included in this meta-analysis
| Â | Â | N of subjects | Age of subjects (years) | Duration (weeks) | Jadad score | Mean baseline blood pressure systolic/diastolic (mm Hg) | |||
|---|---|---|---|---|---|---|---|---|---|
| Â | Â | White | Black | White | Black | White | Black | ||
1 | Study Group 1982 [26] | 170 | 151 | 55 | Â | 7 | 3 | 148.2/97.4 | 147.6/97.8 |
2 | Weinberger 1985 [27] | 32 | 37 | * | * | 6 | 0 | 149.5/99.6 | 152.7/99.2 |
3 | Thind 1988 [28] | 15 | 10 | 47.5 | Â | 4 | 0 | */97 | */101 |
4a | Materson 1993, young [29] | 39 | 44 | 51 | 49 | 4 | 5 | 149/99 | 147/100 |
4b | Materson 1993, old [29] | 55 | 48 | 66 | Â | 4 | 5 | 154/98 | 157/100 |
5a | Weir 1995, 1Â mg [24] | 51 | 23 | 58.3 | 52.7 | 6 | 5 | 154.8/100.3 | 149.6/100.2 |
5b | Weir 1995, 2Â mg [24] | 53 | 22 | 57.3 | 53.0 | 6 | 5 | 151.9/101.7 | 144.8/100.2 |
5c | Weir 1995, 4Â mg [24] | 53 | 23 | 53.0 | 53.2 | 6 | 5 | 147.6/99.9 | 155.9/102.9 |
6 | Chrysant 1996 [30] | 30 | 10 | 53.7 | Â | 6 | 4 | * | * |
7 | Weir 1998a [32] | 32 | 13 | 51 | Â | 12 | 5 | 145.6/89 | 145.8/91.2 |
8a | Weir 1998b, 20Â mg [31] | 48 | 22 | 55.5 | 51.2 | 4 | 3 | 159.9/103 | 156/105.8 |
8b | Weir 1998b, 40Â mg [31] | 43 | 19 | 55.6 | 51.2 | 4 | 3 | 158.4/102.7 | 157.1/104.8 |
9 | Pahor 2002 [25] | 15 | 18 | 59.5 | Â | 4 | 5 | 140/86 | 144/86 |
10 | 7745 | 1412 | 56.8 | 52.3 | 12 | 1 | 157/94.1 | 156.3/96.5 | |
11 | Mokwe 2004 [33] | 2046 | 533 | 48.9 | 51.9 | 18 | 0 | 152.2/94.9 | 150.9/95.6 |
12 | Moran 2007 [35] | 89 | 72 | 53.8 | 54.0 | 8 | 1 | 147/87 | 151/88 |
13 | Van Rijn-Bikker 2009 [34] | 33 | 48 | 48 | Â | 6 | 3 | 153/95 | 156/99 |