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Table 3 Adjusted associations of patient’s attitudes and beliefs with non-adherence to phosphate binder use

From: Potentially modifiable factors associated with non-adherence to phosphate binder use in patients on hemodialysis

Patient’s attitudes and beliefs

Odds ratioaof Non-adherence(95%Confidence interval)

Minimally adjusteda

Extensively adjusteda

Patient’s attitude regarding or understanding of the time to take the phosphate binder

Rarely or never take the PB > 30 minutes after meals

Ref = 1

Ref = 1

Frequently take the PB > 30 minutes after meals

0.94 (0.52-1.68)

0.87 (0.47-1.61)

Always or almost always take the PB >30 minutes after meals

5.98 (2.03-17.58)

6.15 (2.04-18.50)

Patient’s beliefs about stopping PB use after feeling better

Rarely or never stopped

Ref = 1

Ref = 1

Frequently stopped

1.57 (0.61-4.02)

1.47 (0.55-3.91)

Always or almost always stopped

4.21 (1.41-12.54)

4.54 (1.45-14.25)

Patient’s beliefs about stopping PB use after feeling worse

Rarely or never stopped

Ref = 1

Ref = 1

Frequently stopped

0.82 (0.30-2.27)

0.66 (0.23-1.91)

Always or almost always stopped

7.94 (1.80-35.06)

7.26 (1.62-32.55)

Patient’s report of stopping PB used because he/she did not have the medication

Rarely or never stopped

Ref = 1

Ref = 1

Frequently stopped

1.35 (0.68-2.68)

1.29 (0.63-2.65)

Always or almost always stopped

3.57 (0.75-17.01)

2.77 (0.57-13.47)

Patient-family interactions

bSatisfied with time spent with family and friends

0.97 (0.60-1.57)

1.05 (0.62-1.77)

bSatisfied with support provided by family and friends

0.89 (0.49-1.61)

0.83 (0.44-1.58)

Patient-staff interactions

c Satisfaction with the care provided by the hemodialysis staff

  

Good

Ref = 1

Ref = 1

Very poor to regular

1.11 (0.60-2.04)

1.25 (0.65-2.38)

Very good to the best

1.06 (0.69-1.63)

1.13 (0.71-1.80)

dDialysis staff improved the patient’s ability to cope with the disease

0.62 (0.25-1.50)

0.67 (0.26-1.70)

dDialysis staff encouraged the patient to be independent

0.52 (0.32-0.87)

0.52 (0.30-0.90)

eNephrologist explained PB use

0.22 (0.62-0.78)

0.20 (0.05-0.73)

eDietitian explained PB use

0.96 (0.62-1.47)

1.11 (0.69-1.79)

  1. PB phosphate binder.
  2. aMinimally adjusted odds ratios were adjusted for age, race, sex, education, economic class, living with family, marital status, years on dialysis and dialysis by catheter. Extensively adjusted odds ratios were adjusted for cerebrovascular disease, diabetes, heart failure, ischemic heart disease, peripheral vascular disease, physician-diagnosed depression, depression score, cancer, PTH, albumin-corrected serum calcium, serum phosphorus, blood hemoglobin, serum creatinine and all of the co-variables included in the minimally adjusted model.
  3. bPatient responses were unsatisfied and very unsatisfied compared with satisfied and very satisfied.
  4. c Patient response was very poor to regular compared with very good to the best.
  5. d Patient response was definitely true or mostly true (positive responses) compared with do not know and mostly or definitely false.
  6. e Patient response was yes (positive response) compared with no.