Table 1 Clinical characteristics of cohort stratified by renal histopathology
Crescentic GN n = 18 | Focal GN n = 20 | Mixed n = 27 | Sclerotic n = 11 | p-value | |
|---|---|---|---|---|---|
Mean age at biopsy, years (±SD) | 61 ± 13 | 56 ± 15 | 57 ± 17 | 60 ± 17 | 0.749 |
Female (%) | 7 (38) | 6 (28) | 15 (55) | 5 (50) | 0.354 |
African-American (%) | 1 (5) | 5 (24) | 7 (26) | 1 (10) | 0.240 |
ANCA positive (%) | 16 (89) | 15 (75) | 22 (81) | 9 (82) | 0.749 |
cANCA positive (%) | 12 (67) | 7 (33) | 10 (37) | 1 (10) | 0.018 |
pANCA positive (%) | 4 (22) | 8 (40) | 12 (44) | 8 (73) | 0.064 |
New vasculitis diagnosis at biopsy (%) | 16 (89) | 18 (90) | 20 (74) | 6 (55) | 0.076 |
Clinical vasculitis phenotype | |||||
Granulomatosis with polyangiitis (%) | 15 (83) | 8 (38) | 18 (67) | 2 (20) | 0.002 |
Microscopic polyangiitis (%) | 3 (16) | 11 (55) | 8 (30) | 9 (82) | 0.002 |
Renal limited vasculitis (%) | 0 (0) | 1 (5) | 1 (4) | 0 (0) | 0.719 |