Table 4 Clinical characteristics of the CKD patients according to quartiles of FGF23 levels
| Â | FGF23-Quartile 1 | FGF23-Quartile 2 | FGF23-Quartile 3 | FGF23-Quartile 4 | Â |
|---|---|---|---|---|---|
|  | (n = 47; FGF23, 11–40) | (n = 50; FGF23, 41–63) | (n = 49; FGF23, 64–103) | (n = 49; FG23, 105–2010) | p values |
Age (years) | 67.7 ± 14.2 | 68.5 ± 10.6 | 68.2 ± 10.3 | 70.5 ± 10.0 | 0.65 |
Male | 26 (55) | 33 (66) | 35 (71) | 35 (71) | 0.31 |
Hypertension | 38 (81) | 37 (74) | 48 (98) | 48 (98) | <0.01 |
Diabetes mellitus | 20 (43) | 20 (40) | 29 (59) | 23 (47) | 0.23 |
Smoking | 23 (49) | 29 (58) | 30 (61) | 28 (57) | 0.66 |
Dyslipidemia | 35 (74) | 33 (66) | 35 (71) | 43 (88) | 0.06 |
Body mass index (kg/m2) | 22.2 ± 2.5 | 22.4 ± 5.7 | 22.7 ± 5.4 | 22.7 ± 3.5 | 0.95 |
Proteinuria (g/day) | 1.2 (0.1-3.3) | 0.7 (0.1-2.6) | 2.2 (0.4-4.0) | 1.2 (0.4-3.6) | 0.14 |
C-reactive protein (mg/dL) | 0.05 (0.02-0.12) | 0.09 (0.03-0.22) | 0.13 (0.05-0.26) | 0.09 (0.05-0.35)* | 0.01 |
Hemoglobin (g/dL) | 11.5 ± 2.2 | 11.1 ± 2.1 | 10.6 ± 2.0 | 9.6 ± 1.7** | <0.01 |
Serum corrected calcium (mg/dL) | 9.5 ± 0.6 | 9.4 ± 0.5 | 9.5 ± 0.5 | 9.3 ± 0.6 | 0.19 |
Serum phosphorus (mg/dL) | 3.4 ± 0.5 | 3.5 ± 0.6 | 3.6 ± 0.5 | 4.4 ± 0.9** | <0.01 |
Ca-P product (mg2/dL2) | 32.5 ± 5.6 | 33.3 ± 6.0 | 34.4 ± 4.2 | 40.7 ± 8.5** | <0.01 |
eGFR (ml/min/1.73m2) | 46.9 (27.0-68.9) | 33.6 (17.3-57.9) | 22.0 (16.0-35.0)** | 12.7 (9.0-17.2)** | <0.01 |
CAAC | 23 (49) | 29 (58) | 37 (76) | 39 (80) | <0.01 |