From: FGF-23 associated with the progression of coronary artery calcification in hemodialysis patients
Progressive (n = 36) | Non-progressive (n = 38) | p value | |
---|---|---|---|
Age (years) | 56 ± 13 | 48 ± 14 | 0.02 |
Time on dialysis (months)* | 64 (23–98) | 48 (22–84) | 0.23 |
Kt/V | 1.43 ± 0.43 | 1.44 ± 0.48 | 0.82 |
Vitamin D dose (μg/week)* | 1.50 (0–2.50) | 1.20 (0.11-2.31) | 0.91 |
Calcium (mg/dL) | 9.56 ± 0.79 | 9.38 ± 0.64 | 0.29 |
Phosphorus (mg/dL) | 5.92 ± 1.63 | 4.99 ± 1.25 | 0.008 |
Ca X P (mg2/dL2) | 56.71 ± 16.77 | 46.69 ± 11.56 | 0.004 |
Alkaline phosphatase (U/L)* | 116 (82–177) | 115 (81–192) | 0.80 |
PTH (pg/mL)* | 468 (233–648) | 401 (249–610) | 0.15 |
Uric acid (mg/dL) | 6.47 ± 1.13 | 6.42 ± 1.29 | 0.85 |
Albumin (g/dL) | 3.87 ± 0.30 | 3.96 ± 0.26 | 0.15 |
C-reactive protein (mg/L)* | 8.70 (2.70-19.10) | 7.40 (2.80-17.60) | 0.64 |
Triglyceride (mg/dL)* | 145 (101–209) | 150 (101–225) | 0.20 |
Cholesterol (mg/dL) | 190 ± 55 | 195 ± 47 | 0.69 |
FGF-23 (pg/mL)* | 155 (80–468) | 147 (82–234) | 0.04 |
CACS (baseline)* | 190 (52–935) | 4 (0.30-290) | <0.001 |
CACS (1st year)* | 543 (123–1025) | 1.80 (0.65-41) | <0.001 |