From: FGF-23 associated with the progression of coronary artery calcification in hemodialysis patients
HIGH FGF-23 (n = 37) | LOW FGF-23 (n = 37) | p value | |
---|---|---|---|
Age (years) | 49 ± 14 | 55 ± 14 | 0.06 |
Time on dialysis (months)* | 47 (22–95) | 56 (35–97) | 0.60 |
Kt/V | 1.44 ± 0.44 | 1.42 ± 0.47 | 0.79 |
Vitamin D dose (μg/week)* | 1.60 (0.70-2.93) | 0.87 (0–2.02) | 0.04 |
Calcium (mg/dL) | 9.52 ± 0.59 | 9.41 ± 0.83 | 0.54 |
Phosphorus (mg/dL) | 5.50 ± 1.49 | 5.38 ± 1.54 | 0.74 |
Ca X P (mg2/dL2) | 52.37 ± 14.43 | 50.75 ± 15.90 | 0.65 |
Alkaline phosphatase (U/L)* | 130 (88–216) | 109 (78–174) | 0.51 |
PTH (pg/mL)* | 500 (307–702) | 346 (193–549) | 0.03 |
Uric acid (mg/dL) | 6.15 ± 1.22 | 6.74 ± 1.15 | 0.03 |
Albumin (g/dL) | 3.94 ± 0.28 | 3.90 ± 0.29 | 0.57 |
C-reactive protein (mg/L)* | 5.50 (2.37-12.87) | 12.35 (3.85-19.10) | 0.68 |
Hemoglobin (g/dL) | 11.94 ± 1.33 | 11.65 ± 1.56 | 0.40 |
CACS (baseline)* | 47 (0.50 - 549) | 68 (7–807) | 0.95 |
CACS (1st year)* | 96 (1–783) | 173 (3–799) | 0.64 |
∆CACS* | 18 (0–96) | 2 (0–131) | 0.21 |
% ∆CACS* | 17 (0–198) | 7 (0–57) | 0.19 |