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Table 3 Comparison results of the high and low FGF-23 groups in terms of biochemical and CACS values

From: FGF-23 associated with the progression of coronary artery calcification in hemodialysis patients

 

HIGH FGF-23 (n = 37)

LOW FGF-23 (n = 37)

p value

Age (years)

49 ± 14

55 ± 14

0.06

Time on dialysis (months)*

47 (22–95)

56 (35–97)

0.60

Kt/V

1.44 ± 0.44

1.42 ± 0.47

0.79

Vitamin D dose (μg/week)*

1.60 (0.70-2.93)

0.87 (0–2.02)

0.04

Calcium (mg/dL)

9.52 ± 0.59

9.41 ± 0.83

0.54

Phosphorus (mg/dL)

5.50 ± 1.49

5.38 ± 1.54

0.74

Ca X P (mg2/dL2)

52.37 ± 14.43

50.75 ± 15.90

0.65

Alkaline phosphatase (U/L)*

130 (88–216)

109 (78–174)

0.51

PTH (pg/mL)*

500 (307–702)

346 (193–549)

0.03

Uric acid (mg/dL)

6.15 ± 1.22

6.74 ± 1.15

0.03

Albumin (g/dL)

3.94 ± 0.28

3.90 ± 0.29

0.57

C-reactive protein (mg/L)*

5.50 (2.37-12.87)

12.35 (3.85-19.10)

0.68

Hemoglobin (g/dL)

11.94 ± 1.33

11.65 ± 1.56

0.40

CACS (baseline)*

47 (0.50 - 549)

68 (7–807)

0.95

CACS (1st year)*

96 (1–783)

173 (3–799)

0.64

∆CACS*

18 (0–96)

2 (0–131)

0.21

% ∆CACS*

17 (0–198)

7 (0–57)

0.19

  1. (FGF-23: fibroblast growth factor-23, CACS: coronary artery calcification score, PTH: parathyroid hormone) *Median (IQR). Δ: Delta.