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Table 2 Effect of vitamin C supplementation on parameters during 6 months (n = 100)

From: Cross-over study of influence of oral vitamin C supplementation on inflammatory status in maintenance hemodialysis patients

Item

Group 1 (n = 48)

Group 2 (n = 52)

 

Baseline

Month 3

Month 6

Baseline

Month 3

Month 6

prealbumin (mg/l)

295.6 ± 86.6

296.7 ± 60.1

272.1 ± 69.3

315.3 ± 85.8

302.9 ± 60.3

336.9 ± 69.5a

albumin (g/l)

38.2 ± 3.7

38.3 ± 3.1

37.6 ± 2.6

40.0 ± 4.2

39.6 ± 2.8

40.4 ± 2.4

hemoglobin (g/l)

107.2 ± 16.6

109.9 ± 14.1

109.3 ± 14.2

111.4 ± 17.3

110.9 ± 20.4

111.9 ± 25.4

ERI

10.7 ± 8.6

8.3 ± 6.6

9.1 ± 7.4

9.3 ± 6.1

8.6 ± 6.7

7.5 ± 6.4

Ferritin (ug/l)

417.8 ± 266.5

355.0 ± 256.4

444.2 ± 333.5

461.9 ± 287.1

500.0 ± 314.2

445.9 ± 352.7

Vitamin C (μg/mL)

1.5 ± 0.8

10.4 ± 10.3b

2.1 ± 1.6c

2.0 ± 0.9

2.1 ± 1.3

9.1 ± 4.3bc

  

Median(IQR)

  

Median(IQR)

 

rHuEpo (x103U/week)

6.0(3.0-9.0)

4.5(2.8-6.0)

5.2(2.6-8.8)

6.0(4.0-8.8)

6.0(3.0-8.8)

4.2(2.7-6.0)

hsCRP (mg/l)

9.6 (6.0-13.8)

4.9(3.7-8.7)b

8.1(5.1-11.3)d

6.2(4.2-11.0)

7.1(5.2-8.8)

5.1(2.6-6.5)bc

  1. Note: ap < 0.05:compared with group baseline; bp < 0.01:compared with group baseline; cp < 0.01:compared with group Month 3; dp < 0.05:compared with group Month 3; prealbumin, albumin, hemoglobin, ERI, ferritin and vitamin C levels were presented as mean ± SD; EPO dosage and hs-CRP level were presented as median and inter-quartile range (IQR).
  2. Abbreviations: ERI EPO resistance index, rHuEpo, recombinant human erythropoietin, hs-CRP high hypersensitive C-reactive protein, IQR inter quartile range.