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Table 2 Effect of vitamin C supplementation on parameters during 6 months (n = 100)

From: Cross-over study of influence of oral vitamin C supplementation on inflammatory status in maintenance hemodialysis patients

Item Group 1 (n = 48) Group 2 (n = 52)
  Baseline Month 3 Month 6 Baseline Month 3 Month 6
prealbumin (mg/l) 295.6 ± 86.6 296.7 ± 60.1 272.1 ± 69.3 315.3 ± 85.8 302.9 ± 60.3 336.9 ± 69.5a
albumin (g/l) 38.2 ± 3.7 38.3 ± 3.1 37.6 ± 2.6 40.0 ± 4.2 39.6 ± 2.8 40.4 ± 2.4
hemoglobin (g/l) 107.2 ± 16.6 109.9 ± 14.1 109.3 ± 14.2 111.4 ± 17.3 110.9 ± 20.4 111.9 ± 25.4
ERI 10.7 ± 8.6 8.3 ± 6.6 9.1 ± 7.4 9.3 ± 6.1 8.6 ± 6.7 7.5 ± 6.4
Ferritin (ug/l) 417.8 ± 266.5 355.0 ± 256.4 444.2 ± 333.5 461.9 ± 287.1 500.0 ± 314.2 445.9 ± 352.7
Vitamin C (μg/mL) 1.5 ± 0.8 10.4 ± 10.3b 2.1 ± 1.6c 2.0 ± 0.9 2.1 ± 1.3 9.1 ± 4.3bc
   Median(IQR)    Median(IQR)  
rHuEpo (x103U/week) 6.0(3.0-9.0) 4.5(2.8-6.0) 5.2(2.6-8.8) 6.0(4.0-8.8) 6.0(3.0-8.8) 4.2(2.7-6.0)
hsCRP (mg/l) 9.6 (6.0-13.8) 4.9(3.7-8.7)b 8.1(5.1-11.3)d 6.2(4.2-11.0) 7.1(5.2-8.8) 5.1(2.6-6.5)bc
  1. Note: ap < 0.05:compared with group baseline; bp < 0.01:compared with group baseline; cp < 0.01:compared with group Month 3; dp < 0.05:compared with group Month 3; prealbumin, albumin, hemoglobin, ERI, ferritin and vitamin C levels were presented as mean ± SD; EPO dosage and hs-CRP level were presented as median and inter-quartile range (IQR).
  2. Abbreviations: ERI EPO resistance index, rHuEpo, recombinant human erythropoietin, hs-CRP high hypersensitive C-reactive protein, IQR inter quartile range.