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Table 1 Time courses of coagulation and inflammation profile associated with microangiopathic hemolytic parameters

From: Renal thrombotic microangiopathy in a patient with septic disseminated intravascular coagulation

 

Day 1

Day 2

Day 3

Day 4

Day 5

Day 6

Day 7

Platelet count (×104/μL)

23.0

4.5

2.2

2.3

2.4

1.0

3.2

LDH (mg/dL)

217

1160

2267

1836

1412

1482

 

Serum Cr (mg/dL)

0.51

2.09

3.35

  

3.82

4.07

APTT (seconds)

 

51

  

39

32

28

PT-INR

 

1.63

1.36

1.52

1.03

0.90

0.95

FDP (μg/mL)

 

645

259

60

30

  

D-dimer (μg/mL)

  

103.4

    

Fibrinogen (mg/dL)

 

206

425

537

526

566

588

Anti-thrombin III (%)

 

90

60

74

49

 

62

Protein-C (%)

 

<1.0

 

23

<1.0

 

32

PAI-1 (ng/mL)

 

146.8

148.0

172.6

24.7

 

38.7

Procalcitonin (ng/mL)

 

141.9

195.1

125.6

94.9

 

33.6

CRP (mg/dL)

0.66

6.91

15.79

19.77

 

13.53

11.73

  1. The coagulation profiles of APTT and PT were normalized on day 6 as a result of the treatment with antibiotics and continuous hemodiafiltration (CHDF). Antithrombin III (1500 unit) was administered on day 3.