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Table 1 Clinical data of patients with CKD 3, CAD and control group

From: Circulating dendritic cell precursors in chronic kidney disease: a cross-sectional study

 

Control

CKD 3

P-Value1

CAD

P-Value2

P-Value3

(n = 85)

(n = 245)

(n = 130)

Age (years)

58 (21, 78)

66 (30, 75)

< 0.00

66 (38, 85)

n.s.

< 0.001

58 ± 11

64 ± 9

 

64 ± 11

Male gender (%)

43

60

0.010

57

n.s.

0.035

Diabetes mellitus (%)

13

38

< 0.001

15

< 0.001

< 0.001

Hypertension (%)

71

90

< 0.001

72

< 0.001

< 0.001

Smoking (%) (current and ex-smoking)

38

51

n.s.

43

n.s.

n.s.

C-Reactive protein (mg/L)

2.0 (2.0, 9.0)

2.1 (2.0, 9.4)

n.s.

2.0 (2.0, 9.0)

n.s.

n.s.

2.9 ± 1.5

3.3 ± 1.9

 

3.3 ± 1.9

 

Leukocytes (Gpt/L)

6.9 (4.2, 12.0)

6.4 (3.6, 12.7)

0.004

7.3 (3.7, 17.1)

< 0.001

< 0.001

7.1 ± 1.5

6.5 ± 1.6

 

7.5 ± 2.3

GFR (mL/min/1.73 m2)

83 (60, 215)

46 (30, 60)

< 0.001

72 (60, 119)

< 0.001

< 0.001

85 ± 20

45 ± 9

 

75 ± 11

Creatinine (mg/dL)

0.88 (0.34, 1.26)

1.46 (0.75, 3.35)

< 0.001

0.98 (0.69, 1.30)

< 0.001

< 0.001

0.87 ± 0.15

1.52 ± 0.46

 

1.00 ± 0.14

Cholesterol (mg/dL)

217 (121, 328)

203 (91, 411)

0.001

198 (108, 355)

n.s.

0.008

222 ± 47

206 ± 49

 

201 ± 46

HDL (mg/dL)

56 (24, 108)

48 (21, 119)

0.014

47 (31, 82)

n.s.

0.012

56 ± 17

51 ± 17

 

49 ± 11

LDL (mg/dL)

135 (65, 218)

109 (21, 278)

< 0.001

131 (64, 226)

< 0.001

< 0.001

141 ± 37

113 ± 43

 

132 ± 35

TG (mg/dL)

127 (48, 514)

184 (37, 806)

< 0.001

147 (44, 756)

0.018

< 0.001

148 ± 80

203 ± 117

 

176 ± 108

DCP count

      

mDCP rel.

0.22 (0.09, 0.58)

0.17 (0.04, 0.44)

< 0.001

0.21 (0.01, 0.47)

<0.001

< 0.001

(% of WBC)

0.24 ± 0.10

0.18 ± 0.07

 

0.22 ± 0.10

pDCP rel.

0.13 (0.04, 0.30)

0.08 (0.02, 0.40)

< 0.001

0.11 (0.00, 0.32)

< 0.001

< 0.001

(% of WBC)

0.14 ± 0.06

0.09 ± 0.04

 

0.11 ± 0.06

tDCP rel.

0.38 (0.15, 0.76)

0.26 (0.09, 0.58)

< 0.001

0.34 (0.02, 0.72)

< 0.001

< 0.001

(% of WBC)

0.39 ± 0.13

0.27 ± 0.10

 

0.34 ± 0.14

mDCP abs.

15.3 (5.2, 34.4)

10.8 (3.2, 35.6)

< 0.001

14.8 (1.5, 35.0)

<0.0001

< 0.001

(cells per μL)

16.8 ± 7.2

11.4 ± 4.7

 

15.8 ± 7.0

pDCP abs.

8.9 (2.5, 16.5)

5.0 (1.1, 16.7)

< 0.001

7.4 (0.0, 25.8)

< 0.001

< 0.001

(cells per μL)

9.2 ± 3.7

5.5 ± 2.7

 

8.4 ± 5.2

tDCP abs.

27.3 (9.6, 67.8)

16.8 (4.3, 46.2)

< 0.001

24.1 (1.7, 48.8)

< 0.001

< 0.001

(cells per μL)

27.2 ± 10.0

17.5 ± 6.1

 

25.1 ± 10.5

  1. 1CKD 3 compared to control.
  2. 2CAD compared to CKD 3.
  3. According to Student’s t-test, Mann-Whitney-test or chi-square statistics, as appropriate.
  4. 3For differences between any group, according to Kruskal-Wallis-Test or chi-square statistics as appropriate.
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BMC Nephrology

ISSN: 1471-2369

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