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Table 5 Patients with impaired baseline creatinine clearance (< 60 ml/min)

From: The relationship between preoperative creatinine clearance and outcomes for patients undergoing liver transplantation: a retrospective observational study

 

Group 3 (n=10)

Group 4 (n=25)

p-value

Gender (m/f)

10/0

20/5

0.12

Age (yrs.)

56 (36–68)

49 (23–70)

0.18

BMI (kg/m2)

26.7 (23.2–31.8)

23.7 (18.7–33.0)

0.03

Hematocrit before TPL (%)

26.8 (18.4–38.3)

28.2 (21.6–40.7)

0.56

Platelets before TPL (103/μl)

51 (40–158)

83 (22–253)

0.97

MELD (corrected)

22 (19–33)

23 (11–36)

0.55

MELD (uncorrected)

21 (19–28)

16 (6–36)

0.19

CHILD (A/B/C in %)

0/0/100

15/20/65

0.15

Diabetes mellitus (%)

10.0%

8.0%

0.85

Admission from (Home/ward/ICU in %)

30.0/40.0/30.0

60.0/28.0/12.0

0.23

ASA class (II/III/IV in %)

0/30.0/70.0

8.0/28.0/64.0

0.65

Operating time (min)

362 (250–660)

367 (260–480)

0.50

Estimated intraoperative Blood loss (ml)

3000 (200–10000)

1500 (500–8000)

0.31

Marginal grafts (%)

60

36

0.19

Transfusion of - RBC (Unit)

13 (2–39)

7 (0–20)

0.02

- FFP (Unit)

10 (0–55)

14 (0–36)

0.85

- Platelets (Units)

3 (0–6)

1 (0–12)

0.22

- Fibrinogen (g)

7 (0–22)

2 (0–20)

0.04

Length of stay in ICU (days)

10 (5–94)

4 (2–18)

0.0002

Readmissions (%)

60.0

16.0

0.03

Incidence of Sepsis (%)

20.0

0

0.02

Incidence of Respiratory Failure (w. reintubation) (%)

30.0

4.0

0.04

Reoperations (%)

50.0

12.0

0.04

Bilirubin peak (μmol/l)

128 (57–535)

119(14–568)

0.42

ALT peak (U/l)

656 (133–8492)

632 (95–4727)

0.91

AST peak (U/l)

922 (183–13805)

979 (119–4305)

0.68

  1. Data expressed as median (range) or number of patients (percentage), TPL indicates transplantation, MELD model for end stage liver disease and ICU intensive care unit, respectively.