High serum bicarbonate level within the normal range prevents the progression of chronic kidney disease in elderly chronic kidney disease patients

Table 2 Baseline serum bicarbonate level correlated with other factors

	Univariate linear regression analysis		Multiple linear regression analysis
	Difference in serum bicarbonate level	p	Difference in serum bicarbonate level	p
Age (years)	−0.02	0.64
Female (%)	1.16	0.06	0.80	0.13
Diabetes mellitus (%)	1.35	0.03	1.28	0.033
Hypertension (%)	1.67	0.006	0.63	0.27
BMI (kg/m²)	−0.045	0.73
eGFR	0.13	0.0001	0.094	0.0001
Albumin level (g/dl)	0.44	0.61
Sodium level (mEq/l)	0.23	0.08	0.07	0.52
Potassium level (mEq/l)	−1.66	0.0045	0.035	0.95
24-hour urine protein excretion level (g/day)	−0.58	0.049	−0.22	0.40
RAAS inhibitor (%)	1.59	0.08
Loop diuretic use (%)	−0.64	0.31
Sodium bicarbonate use (%)	−2.70	0.0002	−1.18	0.10

Values are expressed as differences in serum bicarbonate level (estimated parameter) and p values. Multiple linear regression analysis variables include gender, diabetes, hypertension, eGFR, sodium level, potassium level, 24-hour urine protein excretion level, and sodium bicarbonate use.
Abbreviations: BMI Body mass index, eGFR Estimated glomerular filtration rate, RAAS Renin angiotensin aldosterone system.

ISSN: 1471-2369