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Table 2 Postoperative characteristics and outcomes of the liver transplantation cohort stratified by time from AKI to RRT or serum creatinine peak

From: Impact of acute kidney injury exposure period among liver transplantation patients

  Time from AKI onset to RRT or SCr peak
  Less than a week (N = 221) A week or more (N = 94) Total (N = 315) p value
Postoperative pressor drugs 41 (19%) 13 (14%) 54 (17%) 0.309
Nephrotoxic drugs 150 (68%) 60 (64%) 210 (67%) 0.486
Sepsis 82 (37%) 38 (40%) 120 (38%) 0.579
Tacrolimus initially 145 (66%) 80 (85%) 225 (71%) <0.001
Surgical re-intervention 54 (24%) 33 (35%) 87 (28%) 0.053
Severe graft failure 52 (24%) 26 (28%) 78 (25%) 0.437
AKI stage reached     0.005
No AKI 22 (10%) 0 (0%) 22 (7%)  
  1 109 (55%) 42 (45%) 151 (48%)  
  2 59 (30%) 36 (38%) 95 (30%)  
  3 31 (16%) 16 (17%) 47 (15%)  
Required RRT 35 (16%) 13 (14%) 48 (15%) 0.650
Received CRRT 17 (8%) 9 (10%) 26 (8%) 0.579
In-hospital mortality 12 (5%) 8 (8%) 20 (6%) 0.305
Overall mortality 40 (18%) 34 (36%) 74 (24%) 0.001
  1. AKI: acute kidney injury; CRRT: continuous renal replacement therapy; LT: liver transplantation; RRT: renal replacement therapy; SCr: serum creatinine.