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Table 1 Prevalence and main characteristics of patients, according to the presence of proteinuria, dilatation or infection (data at referral and delivery)

From: Excessive urinary tract dilatation and proteinuria in pregnancy: a common and overlooked association?

 

Patients with urinary tract dilatation and proteinuria <0.3 g/day (12 pts)

Patients with urinary tract dilatation and proteinuria ≥0.3 <0.5 g/day (5 pts)

Patients with urinary tract dilatation and proteinuria ≥0.5 g/day (6 pts)

Patients with acute urinary tract infection without dilatation (14 pts)

Mean age (start of pregnancy) ± sd

28.6 ± 5.93

29.2 ± 5.93

29.8 ± 4.49

29.8 ± 6.60

Primiparous n (%)

5 (41.7%)

3 (60%)

2 (33.3%)

9 (64.3%)

Median week of referral

23 (4–36)

8 (5–33)

30 (18–35)

21 (7–36)

Data at referral of pregnancy

Mean creatinine (mg/dl) ± sd

0.6 ± 0.12

0.7 ± 0.09

0.6 ± 0.21

0.6 ± 0.13

GFR (EPI)

124 ± 13

118 ± 12

125 ± 25

120 ± 14

Hypertension

No

No

No

No

Median proteinuria (g/24 h) *

0.1 (0.08-0.31)

0.1 (0.07-0.18)

1.09 (0.1-2.65)

0.1 (0.06-0.53)

“JJ” stenting during pregnancy §

0

1/5

5/6

0

Data at delivery

Mean creatinine (mg/dl) ± sd

0.6 ± 0.15

0.6 ± 0.20

0.7 ± 0.22

0.6 ± 0.12

GFR

124 ± 18

118 ± 26

118 ± 27

117 ± 14

Hypertension

No

No

No

1 (7.1%)

median proteinuria (g/24 h) **

0.1 (0.07-0.16)

0.3 (0.3-0.38)

1.7 (0.6-2.54)

0.1 (0.1-0.23)

Mean gestational age ± sd ***

38.8 ± 1.7

38.6 ± 1.8

35.5 ± 1.8

38.8 ± 1.4

Preterm delivery <37 weeks n (%)§§

2 (16.7%)

0

4 (66.7%)

0

Vaginal delivery

n (%)

10 (83.3%)

2 (40%)

6 (100%)

12 (85.7%)

Weight of newborn ± sd ****

3315.4 ± 548.92

3136 ± 453.02

2553.3 ± 372.86

3236.7 ± 494.7

Newborns ≤10 th centile

0

0

1 (16.7%)

1 (7.1%)

  1. Note: Singletons only; one twin and one triplet pregnancies in the group with dilatation were not considered. One further patient dropped out from follow-up before delivery (also excluded).
  2. All patients underwent at least two measurements of proteinuria on 24 hour urine collections.
  3. * Mann–Whitney test: group 3 versus 1: p= 0.002; versus 2: p=0.019; versus 4 p=0.012.
  4. ** Mann–Whitney test: group 3 versus 1: p= 0.000; versus 2: p=0.005; versus 4 p=0.000.
  5. *** T student test: group 3 versus 1: p= 0.0016; versus 2: p=0.0184; versus 4 p=0.0003.
  6. **** T student test: group 3 versus 1: p= 0.0077; versus 2: p=0.0437; versus 4 p=0.0074.
  7. § Chi square test: group 3 versus 1: p= 0.0016; versus 2: p=0.1356; versus 4 p=0.0007.
  8. §§ Chi square test: group 3 versus 1: p= 0.1160; versus 2: p=0.0971; versus 4 p=0.0050.
  9. Singletons only.